Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3UFJ

Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-fluoro-2'-deoxyuridine

Summary for 3UFJ
Entry DOI10.2210/pdb3ufj/pdb
Related2RBA
DescriptorG/T mismatch-specific thymine DNA glycosylase, 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(UF2)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', ... (4 entities in total)
Functional Keywordsdna damage, dna repair, dna binding, glycosidase, nucleus, hydrolase-dna complex, hydrolase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q13569
Total number of polymer chains6
Total formula weight74425.53
Authors
Pozharski, E.,Maiti, A.,Drohat, A.C. (deposition date: 2011-11-01, release date: 2012-04-25, Last modification date: 2023-09-13)
Primary citationMaiti, A.,Noon, M.S.,Mackerell, A.D.,Pozharski, E.,Drohat, A.C.
Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Proc.Natl.Acad.Sci.USA, 109:8091-8096, 2012
Cited by
PubMed: 22573813
DOI: 10.1073/pnas.1201010109
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.967 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon