3UFJ

Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-fluoro-2'-deoxyuridine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	G/T mismatch-specific thymine DNA glycosylase	polymer	204	23070.7	2	UniProt (Q13569) Pfam (PF03167)	Homo sapiens (human)	Thymine-DNA glycosylase
2	C, E (C, E)	5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3'	polymer	23	7121.6	2
3	D, F (D, F)	5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(UF2)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3'	polymer	23	7020.5	2
4	G (A)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, B: 111 - 308 (UniProt: Q13569)

PDB	External Database	Details
Gly 105	-	expression tag
Ser 106	-	expression tag
His 107	-	expression tag
Met 108	-	expression tag
Ala 109	-	expression tag
Ser 110	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	74425.5
All*	Total formula weight	74425.5

*Water molecules are not included.