2NQ3
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![BU of 2nq3 by Molmil](/molmil-images/mine/2nq3) | Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase | Descriptor: | CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-10-30 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase To be Published
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5CCJ
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1W15
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![BU of 1w15 by Molmil](/molmil-images/mine/1w15) | rat synaptotagmin 4 C2B domain in the presence of calcium | Descriptor: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | Authors: | Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J. | Deposit date: | 2004-06-16 | Release date: | 2004-08-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4 Nat.Struct.Mol.Biol., 11, 2004
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1W16
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![BU of 1w16 by Molmil](/molmil-images/mine/1w16) | rat synaptotagmin 4 C2B domain in the absence of calcium | Descriptor: | CHLORIDE ION, SODIUM ION, SYNAPTOTAGMIN IV | Authors: | Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J. | Deposit date: | 2004-06-16 | Release date: | 2004-08-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4 Nat.Struct.Mol.Biol., 11, 2004
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5A51
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8FAM
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![BU of 8fam by Molmil](/molmil-images/mine/8fam) | Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature | Descriptor: | Synaptotagmin | Authors: | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B. | Deposit date: | 2022-11-28 | Release date: | 2023-07-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
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2NSQ
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![BU of 2nsq by Molmil](/molmil-images/mine/2nsq) | Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-11-06 | Release date: | 2006-12-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein To be Published
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4ICX
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8FAF
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![BU of 8faf by Molmil](/molmil-images/mine/8faf) | Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature | Descriptor: | Synaptotagmin | Authors: | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B. | Deposit date: | 2022-11-26 | Release date: | 2023-07-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
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4IHB
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4ICW
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2Q3X
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![BU of 2q3x by Molmil](/molmil-images/mine/2q3x) | The RIM1alpha C2B domain | Descriptor: | CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ... | Authors: | Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J. | Deposit date: | 2007-05-30 | Release date: | 2007-08-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution. Biochemistry, 46, 2007
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4IQH
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3PYC
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![BU of 3pyc by Molmil](/molmil-images/mine/3pyc) | Crystal structure of human SMURF1 C2 domain | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase SMURF1, SULFATE ION | Authors: | Li, X, Li, P. | Deposit date: | 2010-12-13 | Release date: | 2011-04-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of human SMURF1 C2 domain To be Published
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2B3R
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![BU of 2b3r by Molmil](/molmil-images/mine/2b3r) | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2 | Descriptor: | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide, SULFATE ION | Authors: | Liu, L, Song, X, He, D, Komma, C, Kita, A, Verbasius, J.V, Bellamy, H, Miki, K, Czech, M.P, Zhou, G.W. | Deposit date: | 2005-09-20 | Release date: | 2005-12-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2alpha. J.Biol.Chem., 281, 2006
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6ANK
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![BU of 6ank by Molmil](/molmil-images/mine/6ank) | Synaptotagmin-7, C2A- and C2B-domains | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 | Authors: | Tomchick, D.R, Rizo, J, Voleti, R. | Deposit date: | 2017-08-13 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.254 Å) | Cite: | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6BTY
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![BU of 6bty by Molmil](/molmil-images/mine/6bty) | Crystal structure of the PI3KC2alpha C2 domain in space group P41212 | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | Authors: | Chen, K.-E, Collins, B.M. | Deposit date: | 2017-12-08 | Release date: | 2018-10-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.678 Å) | Cite: | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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6BTZ
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![BU of 6btz by Molmil](/molmil-images/mine/6btz) | Crystal structure of the PI3KC2alpha C2 domain in space group C121 | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ... | Authors: | Chen, K.-E, Collins, B.M. | Deposit date: | 2017-12-08 | Release date: | 2018-10-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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6BU0
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![BU of 6bu0 by Molmil](/molmil-images/mine/6bu0) | Crystal structure of the PI3KC2alpha C2 domain in complex with IP6 | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Chen, K.-E, Collins, B.M. | Deposit date: | 2017-12-08 | Release date: | 2018-10-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.427 Å) | Cite: | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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4RJ9
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![BU of 4rj9 by Molmil](/molmil-images/mine/4rj9) | Structure of a plant specific C2 domain protein, OsGAP1 from rice | Descriptor: | C2 domain-containing protein-like, POTASSIUM ION | Authors: | Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M. | Deposit date: | 2014-10-08 | Release date: | 2015-08-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1). J.Biol.Chem., 290, 2015
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6CXW
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6ANJ
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![BU of 6anj by Molmil](/molmil-images/mine/6anj) | Synaptotagmin-7, C2A domain | Descriptor: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | Authors: | Tomchick, D.R, Rizo, J, Voleti, R. | Deposit date: | 2017-08-13 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4TS6
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3F05
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3F00
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