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3N5C	Crystal Structure of Arf6DELTA13 complexed with GDP Descriptor: ADP-ribosylation factor 6, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE Authors: Aizel, K, Biou, V, Cherfils, J. Deposit date: 2010-05-25 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.82 Å) Cite: SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6. J.Mol.Biol., 402, 2010
3MYE	Crystal Structure of HP67 L61GL Descriptor: Villin-1 Authors: Brown, J.W, Farelli, J.D, McKnight, C.J. Deposit date: 2010-05-10 Release date: 2011-05-25 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Conserving the Hydrophobic Core at the Expense of Backbone Conformation in Villin Headpiece To be Published
3NKJ	Crystal Structure of HP67 L61G Descriptor: Villin-1 Authors: Brown, J.W, Farelli, J.D, McKnight, C.J. Deposit date: 2010-06-20 Release date: 2011-06-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Conserving the Hydrophobic Core at the Expense of Backbone Conformation in Villin Headpiece To be Published
6AJ4	Crystal structure of the DHR-2 domain of DOCK7 in complex with Cdc42 Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 Authors: Kukimoto-Niino, M, Shirouzu, M. Deposit date: 2018-08-27 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.256 Å) Cite: Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
6AJL	DOCK7 mutant I1836Y complexed with Cdc42 Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 Authors: Kukimoto-Niino, M, Shirouzu, M. Deposit date: 2018-08-28 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.23 Å) Cite: Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
3I9Q	Crystal Structure of the triple mutant S19G-P20D-R21S of alpha spectrin SH3 domain Descriptor: SULFATE ION, Spectrin alpha chain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2009-07-12 Release date: 2009-12-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The effect of a proline residue on the rate of growth and the space group of alpha-spectrin SH3-domain crystals. Acta Crystallogr.,Sect.D, 65, 2009
3F57	Crystal structure of human erythroid beta spectrin repeats 14 and 15 (ankyrin binding domain) Descriptor: Spectrin beta chain, erythrocyte Authors: Ipsaro, J.J, Mondragon, A. Deposit date: 2008-11-03 Release date: 2009-02-24 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of the spectrin-ankyrin interaction binding domains. Blood, 113, 2009
5O2Z	Domain swap dimer of the G167R variant of gelsolin second domain Descriptor: ACETATE ION, CALCIUM ION, CITRATE ANION, ... Authors: Boni, F, Milani, M, Mastrangelo, E, de Rosa, M. Deposit date: 2017-05-23 Release date: 2017-11-08 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein. Hum. Mol. Genet., 27, 2018
5KZS	Listeria monocytogenes internalin-like protein lmo2027 Descriptor: Putative cell surface protein, similar to internalin proteins Authors: Light, S.H, Nocadello, S, Minasov, G, Cardona-Correa, A, Kwon, K, Faralla, C, Bakardjiev, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2016-07-25 Release date: 2017-07-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Listeria monocytogenes InlP interacts with afadin and facilitates basement membrane crossing. Plos Pathog., 14, 2018
5WBY	Crystal structure of mTOR(deltaN)-mLST8-PRAS40(beta-strand) complex Descriptor: Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 Authors: Pavletich, N.P, Yang, H. Deposit date: 2017-06-29 Release date: 2017-12-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
5CX2	Structure of coiled coil domain of Leishmania donovani coronin Descriptor: 1,2-ETHANEDIOL, Coronin, SULFATE ION Authors: Nayak, A.R, Karade, S.S, Srivastava, V.K, Pratap, J.V. Deposit date: 2015-07-28 Release date: 2016-07-27 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Structure of Leishmania donovani coronin coiled coil domain reveals an antiparallel 4 helix bundle with inherent asymmetry J.Struct.Biol., 195, 2016
5WBU	Crystal structure of mTOR(deltaN)-mLST8-PRAS40(alpha-helix & beta-strand) complex Descriptor: Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 Authors: Pavletich, N.P, Yang, H. Deposit date: 2017-06-29 Release date: 2017-12-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.42 Å) Cite: Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
5FAE	N184K pathological variant of gelsolin domain 2 (trigonal form) Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Boni, F, Milani, M, Ricagno, S, Bolognesi, M, de Rosa, M. Deposit date: 2015-12-11 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant. Sci Rep, 6, 2016
6MZC	Human TFIID BC core Descriptor: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 2, ... Authors: Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
6MIZ	Human TRPM2 ion channel in an ADPR-bound state Descriptor: Transient receptor potential cation channel subfamily M member 2 Authors: Wang, L, Fu, T.M, Xia, S, Wu, H. Deposit date: 2018-09-20 Release date: 2018-12-12 Last modified: 2019-01-02 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Structures and gating mechanism of human TRPM2. Science, 362, 2018
6MSU	Integrin alphaVBeta3 in complex with EETI-II 2.5F Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... Authors: van Agthoven, J.F, Arnaout, M.A. Deposit date: 2018-10-18 Release date: 2019-10-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1. Structure, 27, 2019
6MWQ	Single particle cryoEM structure of a DARPin-aldolase platform in complex with GFP Descriptor: DARPin, Muscle-type aldolase chimeric fusion, Green fluorescent protein Authors: Weaver, S.J, Yao, Q. Deposit date: 2018-10-30 Release date: 2018-11-21 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3 Å) Cite: Fusion of DARPin to Aldolase Enables Visualization of Small Protein by Cryo-EM. Structure, 27, 2019
6MZM	Human TFIID bound to promoter DNA and TFIIA Descriptor: SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... Authors: Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (7.5 Å) Cite: Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
6MZD	Human TFIID Lobe A canonical Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... Authors: Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (9.8 Å) Cite: Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
7O0B	TRIM3 Filamin domain Descriptor: Tripartite motif-containing protein 3 Authors: Williams, F.P, Yikilmazsoy, A, Hennig, J. Deposit date: 2021-03-26 Release date: 2022-04-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.13 Å) Cite: TRIM3 Filamin domain To be published
6N89	Cryo-EM structure of the Importin beta:Histone H1.0 complex Descriptor: Histone H1.0, Importin subunit beta-1 Authors: Bilokapic, S, Ivic, N, Halic, M. Deposit date: 2018-11-28 Release date: 2019-02-27 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (7.5 Å) Cite: Fuzzy Interactions Form and Shape the Histone Transport Complex. Mol. Cell, 73, 2019
6MZL	Human TFIID canonical state Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... Authors: Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2019-11-20 Method: ELECTRON MICROSCOPY (23 Å) Cite: Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
2C2H	CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Debreczeni, J.E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, von Delft, F, Doyle, D, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A. Deposit date: 2005-09-29 Release date: 2005-10-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structure of the Human Rac3 in Complex with Gdp To be Published
6NAJ	Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ... Authors: van Agthoven, J, Arnaout, M.A. Deposit date: 2018-12-05 Release date: 2019-12-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure-guided design of pure orthosteric inhibitors of alpha IIb beta 3 that prevent thrombosis but preserve hemostasis. Nat Commun, 11, 2020
6NIF	crystal structure of human REV7-RAN complex Descriptor: hREV7, GTP-binding nuclear protein Ran, hREV3 fusion Authors: Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. Deposit date: 2018-12-27 Release date: 2019-09-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.002 Å) Cite: REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294, 2019

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