6MSU

Integrin alphaVBeta3 in complex with EETI-II 2.5F

Summary for 6MSU

• Entry DOI: 10.2210/pdb6msu/pdb
• Related: 3IJE 4G1E 4G1M 4MMX 4MMY 4MMZ
• Descriptor: Integrin alpha-V, CHLORIDE ION, Integrin beta-3, ... (11 entities in total)
• Functional Keywords: hybrid domain, psi, egf repeats, beta tail, calf, thigh, beta propeller, rgd motif, fibronectin, vitronectin, cell adhesion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 194125.89

Authors

van Agthoven, J.F.,Arnaout, M.A. (deposition date: 2018-10-18, release date: 2019-10-23, Last modification date: 2023-10-11)

• Primary citation: Van Agthoven, J.F.,Shams, H.,Cochran, F.V.,Alonso, J.L.,Kintzing, J.R.,Garakani, K.,Adair, B.D.,Xiong, J.P.,Mofrad, M.R.K.,Cochran, J.R.,Arnaout, M.A.; Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1.; Structure, 27:1443-1451.e6, 2019; PubMed: 31353240; DOI: 10.1016/j.str.2019.06.011

Experimental method

X-RAY DIFFRACTION (3.11 Å)