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6CJC
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BU of 6cjc by Molmil
CRYSTAL STRUCTURE OF A FC FRAGMENT LALA MUTANT (L234A, L235A) OF HUMAN IGG1 (CRYSTAL FORM 3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Uncharacterized protein DKFZp686C11235
Authors:Tolbert, W.D, Van, V, Pazgier, M.
Deposit date:2018-02-26
Release date:2019-03-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.575 Å)
Cite:Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding.
Structure, 28, 2020
6CHF
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BU of 6chf by Molmil
Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uncharacterized protein DKFZp686C11235
Authors:Gohain, N, Tolbert, W.D, Pazgier, M.
Deposit date:2018-02-22
Release date:2019-02-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding.
Structure, 2020
8BL3
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BU of 8bl3 by Molmil
De novo single-chain immunoglobulin dimer scIg12
Descriptor: GLYCEROL, scIg12
Authors:Nadal, M, Roel-Touris, J, Marcos, E.
Deposit date:2022-11-09
Release date:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Single-chain dimers from de novo immunoglobulins as robust scaffolds for multiple binding loops.
Nat Commun, 14, 2023
8BL6
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BU of 8bl6 by Molmil
De novo single-chain immunoglobulin dimer scIg12+EF3a
Descriptor: GLYCEROL, TERBIUM(III) ION, dIG14-scdim-EF62
Authors:Nadal, M, Roel-Touris, J, Marcos, E.
Deposit date:2022-11-09
Release date:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Single-chain dimers from de novo immunoglobulins as robust scaffolds for multiple binding loops.
Nat Commun, 14, 2023
5JLZ
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BU of 5jlz by Molmil
Crystal structure of HLA-DRB1*04:01 in complex with modified alpha-enolase peptide 26-40 with citrulline at the position 32
Descriptor: Alpha-enolase, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Dubnovitsky, A, Kozhukh, G, Sandalova, T, Achour, A.
Deposit date:2016-04-28
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis.
Front Immunol, 7, 2016
4K5C
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BU of 4k5c by Molmil
From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display
Descriptor: Loop Designed Ankyrin Repeat Protein Nran1_G06_C
Authors:Schilling, J, Schoeppe, J, Plueckthun, A.
Deposit date:2013-04-14
Release date:2013-11-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display
J.Mol.Biol., 426, 2014
5NIU
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BU of 5niu by Molmil
Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor
Descriptor: (2~{R})-2-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-phenyl]methoxy]-5-methyl-phenyl]methylamino]-3-oxidanyl-propanoic acid, 1,2-ETHANEDIOL, Programmed cell death 1 ligand 1
Authors:Zak, K.M, Grudnik, P, Skalniak, L, Dubin, G, Holak, T.A.
Deposit date:2017-03-27
Release date:2017-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.
Oncotarget, 8, 2017
3VCM
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BU of 3vcm by Molmil
Crystal structure of human prorenin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, prorenin
Authors:Morales, R, Watier, Y, Bocskei, Z.
Deposit date:2012-01-04
Release date:2012-05-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Human Prorenin Structure Sheds Light on a Novel Mechanism of Its Autoinhibition and on Its Non-Proteolytic Activation by the (Pro)renin Receptor.
J.Mol.Biol., 421, 2012
7NLL
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BU of 7nll by Molmil
SARS-CoV-2 Spike RBD (dimer) in complex with two Fu2 nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Fu2, Spike protein S1
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-02-22
Release date:2022-02-02
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Nat Commun, 13, 2022
7NS6
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BU of 7ns6 by Molmil
SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fu2 nanobody, Spike glycoprotein,Fibritin, ...
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-03-05
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Nat Commun, 13, 2022
1W6Z
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BU of 1w6z by Molmil
High Energy Tetragonal Lysozyme X-ray Structure
Descriptor: CHLORIDE ION, HOLMIUM (III) ATOM, LYSOZYME C
Authors:Jakoncic, J, Aslantas, M, Honkimaki, V, Di Michiel, M, Stojanoff, V.
Deposit date:2004-08-25
Release date:2004-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Anomalous Diffraction at Ultra-High Energy for Protein Crystallography.
J.Appl.Crystallogr., 39, 2006
2XBS
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BU of 2xbs by Molmil
Raman crystallography of Hen White Egg Lysozyme - High X-ray dose (16 MGy)
Descriptor: CHLORIDE ION, LYSOZYME C
Authors:Carpentier, P, Royant, A, Weik, M, Bourgeois, D.
Deposit date:2010-04-14
Release date:2010-11-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Raman Assisted Crystallography Reveals a Mechanism of X-Ray Induced Reversible Disulfide Radical Formation
Structure, 18, 2010
2XBR
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BU of 2xbr by Molmil
Raman crystallography of Hen White Egg Lysozyme - Low X-ray dose (0.2 MGy)
Descriptor: CHLORIDE ION, LYSOZYME C
Authors:Carpentier, P, Royant, A, Weik, M, Bourgeois, D.
Deposit date:2010-04-14
Release date:2010-11-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Raman Assisted Crystallography Reveals a Mechanism of X-Ray Induced Reversible Disulfide Radical Formation
Structure, 18, 2010
5L1X
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BU of 5l1x by Molmil
Structure of the Human Metapneumovirus Fusion Protein in the Postfusion Conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mas, V, Melero, J.A, McLellan, J.S.
Deposit date:2016-07-29
Release date:2016-08-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.
Plos Pathog., 12, 2016
8BPG
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BU of 8bpg by Molmil
FcMR binding at subunit Fcu3 of IgM pentamer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for Fc receptor recognition of immunoglobulin M.
Nat.Struct.Mol.Biol., 30, 2023
8BPF
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BU of 8bpf by Molmil
FcMR binding at subunit Fcu1 of IgM pentamer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for Fc receptor recognition of immunoglobulin M.
Nat.Struct.Mol.Biol., 30, 2023
8BPE
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BU of 8bpe by Molmil
8:1 binding of FcMR on IgM pentameric core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structural basis for Fc receptor recognition of immunoglobulin M.
Nat.Struct.Mol.Biol., 30, 2023
2YDG
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BU of 2ydg by Molmil
Ascorbate co-crystallized HEWL.
Descriptor: ASCORBIC ACID, Lysozyme C, SODIUM ION
Authors:De la Mora, E, Carmichael, I, Garman, E.F.
Deposit date:2011-03-19
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
2YBN
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BU of 2ybn by Molmil
Nitrate X-ray induced reduction on HEWL crystals (28.6 MGy)
Descriptor: LYSOZYME C, NITRITE ION
Authors:De la Mora, E, Carmichael, I, Garman, E.F.
Deposit date:2011-03-08
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
2YBL
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BU of 2ybl by Molmil
Nitrate X-ray induced reduction on HEWL crystals (17.9 MGy)
Descriptor: LYSOZYME C, NITRITE ION
Authors:De la Mora, E, Carmichaael, I, Garman, E.F.
Deposit date:2011-03-08
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
2YBH
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BU of 2ybh by Molmil
Nitrate X-ray induced reduction on HEWL crystals (2.31 MGy).
Descriptor: LYSOZYME C, NITRATE ION
Authors:De la Mora, E, Carmichael, I, Garman, E.F.
Deposit date:2011-03-08
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
2YBM
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BU of 2ybm by Molmil
Nitrate X-ray induced reduction on HEWL crystals (23.3 MGy)
Descriptor: LYSOZYME C, NITRIC OXIDE
Authors:De la Mora, E, Carmichael, I, Garman, E.F.
Deposit date:2011-03-08
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
2YBJ
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BU of 2ybj by Molmil
Nitrate X-ray induced reduction on HEWL crystals (12.31 MGy)
Descriptor: LYSOZYME C, NITRITE ION
Authors:De la Mora, E, Carmichael, I, Garman, E.F.
Deposit date:2011-03-08
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
2YBI
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BU of 2ybi by Molmil
Nitrate X-ray induced reduction on HEWL crystals (6.62 MGy)
Descriptor: LYSOZYME C, NITRATE ION, NITRITE ION
Authors:De la Mora, E, Carmichael, I, Garman, E.F.
Deposit date:2011-03-08
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
6L1Y
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BU of 6l1y by Molmil
structure of gp120/CD4 with a non-canonical surface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, T-cell surface glycoprotein CD4, ...
Authors:Liu, X, Ning, W.
Deposit date:2019-10-01
Release date:2020-05-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.469 Å)
Cite:A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4.
Sci Rep, 7, 2017

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