3VCM
Crystal structure of human prorenin
Summary for 3VCM
| Entry DOI | 10.2210/pdb3vcm/pdb |
| Descriptor | prorenin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
| Functional Keywords | aspartic proteases, prorenin receptor, hydrolase |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted: P00797 P00797 |
| Total number of polymer chains | 4 |
| Total formula weight | 83894.33 |
| Authors | Morales, R.,Watier, Y.,Bocskei, Z. (deposition date: 2012-01-04, release date: 2012-05-23, Last modification date: 2024-03-06) |
| Primary citation | Morales, R.,Watier, Y.,Bocskei, Z. Human Prorenin Structure Sheds Light on a Novel Mechanism of Its Autoinhibition and on Its Non-Proteolytic Activation by the (Pro)renin Receptor. J.Mol.Biol., 421:100-111, 2012 Cited by PubMed: 22575890DOI: 10.1016/j.jmb.2012.05.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.93 Å) |
Structure validation
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