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2FJR
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BU of 2fjr by Molmil
Crystal Structure of Bacteriophage 186
Descriptor: Repressor protein CI
Authors:Lewis, M.
Deposit date:2006-01-03
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The structural basis of cooperative regulation at an alternate genetic switch
Mol.Cell, 21, 2006
4ESF
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BU of 4esf by Molmil
Crystal structure of PadR-like transcriptional regulator (BCE3449) from Bacillus cereus strain ATCC 10987
Descriptor: PadR-like transcriptional regulator
Authors:Fibriansah, G, Kovacs, A.T, Kuipers, O.P, Thunnissen, A.M.W.H.
Deposit date:2012-04-23
Release date:2012-12-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features of a PadR Subfamily.
Plos One, 7, 2012
4ESB
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BU of 4esb by Molmil
Crystal structure of PadR-like transcriptional regulator (BC4206) from Bacillus cereus strain ATCC 14579
Descriptor: GLYCEROL, SULFATE ION, Transcriptional regulator, ...
Authors:Fibriansah, G, Kovacs, A.T, Kuipers, O.P, Thunnissen, A.M.W.H.
Deposit date:2012-04-23
Release date:2012-12-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features of a PadR Subfamily.
Plos One, 7, 2012
5XAZ
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BU of 5xaz by Molmil
Crystal structure of full length native tylp, a tetr regulator from streptomyces fradiae
Descriptor: Gamma-butyrolactone receptor protein
Authors:Ray, S, Panjikar, S, Anand, R.
Deposit date:2017-03-15
Release date:2017-08-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from Streptomyces fradiae
J. Biol. Chem., 292, 2017
5XAY
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BU of 5xay by Molmil
Crystal structure of full length tylp, a tetr regulator from streptomyces fradiae
Descriptor: Gamma-butyrolactone receptor protein
Authors:Ray, S, Panjikar, S, Anand, R.
Deposit date:2017-03-15
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from Streptomyces fradiae
J. Biol. Chem., 292, 2017
9F14
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BU of 9f14 by Molmil
The crystal structure of full length tetramer CysB from Klebsiella aerogenes in complex with N-acetylserine
Descriptor: HTH-type transcriptional regulator CysB, N-ACETYL-SERINE
Authors:Verschueren, K.H.G, Dodson, E.J, Wilkinson, A.J.
Deposit date:2024-04-18
Release date:2024-07-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structure of the LysR-type Transcriptional Regulator, CysB, Bound to the Inducer, N-acetylserine.
Eur.Biophys.J., 2024
9FDD
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BU of 9fdd by Molmil
The crystal structure of full length tetramer CysB from Klebsiella aerogenes in complex with N-acetylserine
Descriptor: HTH-type transcriptional regulator CysB, N-ACETYL-SERINE
Authors:Verschueren, K.H.G, Dodson, E.J, Wilkinson, A.J.
Deposit date:2024-05-16
Release date:2024-07-03
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the LysR-type Transcriptional Regulator, CysB, Bound to the Inducer, N-acetylserine.
Eur.Biophys.J., 2024
7B5G
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BU of 7b5g by Molmil
Crystal structure of E.coli LexA in complex with nanobody NbSOS3(Nb14527)
Descriptor: 1,2-ETHANEDIOL, LexA repressor, Nanobody Nb14527, ...
Authors:Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L.
Deposit date:2020-12-03
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway.
Structure, 30, 2022
1JHH
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BU of 1jhh by Molmil
LEXA S119A MUTANT
Descriptor: LEXA REPRESSOR, SULFATE ION
Authors:Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J.
Deposit date:2001-06-27
Release date:2001-09-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of LexA: a conformational switch for regulation of self-cleavage.
Cell(Cambridge,Mass.), 106, 2001
7TEA
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BU of 7tea by Molmil
Crystal structure of S. aureus GlnR-DNA complex
Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*TP*GP*TP*CP*AP*GP*AP*TP*AP*AP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*GP*TP*CP*AP*GP*AP*TP*TP*AP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), ...
Authors:Schumacher, M.A.
Deposit date:2022-01-04
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
1JHC
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BU of 1jhc by Molmil
LEXA S119A C-TERMINAL TRYPTIC FRAGMENT
Descriptor: LEXA REPRESSOR
Authors:Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J.
Deposit date:2001-06-27
Release date:2001-09-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of LexA: a conformational switch for regulation of self-cleavage.
Cell(Cambridge,Mass.), 106, 2001
1JHE
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BU of 1jhe by Molmil
LEXA L89P Q92W E152A K156A MUTANT
Descriptor: LEXA REPRESSOR
Authors:Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, J Strynadka, N.C.
Deposit date:2001-06-27
Release date:2001-09-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of LexA: a conformational switch for regulation of self-cleavage.
Cell(Cambridge,Mass.), 106, 2001
8Q9N
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BU of 8q9n by Molmil
Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and MITR deacetylase binding motif mutant L151V.
Descriptor: DIMETHYL SULFOXIDE, DNA MADS box, MEF2D protein, ...
Authors:Chinellato, M, Carli, A, Perin, S, Mazzocato, Y, Biondi, B, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L.
Deposit date:2023-08-20
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J.Mol.Biol., 436, 2024
7ZPN
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BU of 7zpn by Molmil
Crystal Structure of IscR from Dinoroseobacter shibae
Descriptor: GLYCEROL, HTH-type transcriptional regulator, SULFATE ION
Authors:Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E.
Deposit date:2022-04-28
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes
To Be Published
4U4R
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BU of 4u4r by Molmil
Crystal structure of Lactimidomycin bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
7OCJ
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BU of 7ocj by Molmil
Crystal structure of E.coli LexA in complex with nanobody NbSOS2(Nb14509)
Descriptor: 1,2-ETHANEDIOL, LexA repressor, NbSOS2 (14509)
Authors:Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L.
Deposit date:2021-04-27
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway.
Structure, 30, 2022
8PW0
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BU of 8pw0 by Molmil
Manganese-dependent transcriptional repressor DR2539 complexed with manganese and bound to dr1709 promotor
Descriptor: DNA (5'-D(*TP*AP*TP*TP*TP*TP*AP*GP*GP*CP*GP*CP*GP*AP*CP*TP*AP*AP*AP*AP*T)-3'), GLYCEROL, Iron dependent repressor, ...
Authors:Mota, C, De Sanctis, D.
Deposit date:2023-07-18
Release date:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539.
Febs J., 2024
8PVZ
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BU of 8pvz by Molmil
Manganese-dependent transcriptional repressor DR2539 complexed with cadmium
Descriptor: CADMIUM ION, Iron dependent repressor, putative
Authors:Mota, C, De Sanctis, D.
Deposit date:2023-07-18
Release date:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539.
Febs J., 2024
7ZRA
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BU of 7zra by Molmil
Crystal structure of E.coli LexA in complex with nanobody NbSOS1(Nb14497)
Descriptor: 1,2-ETHANEDIOL, LexA repressor, Nanobody NbSOS1 (Nb14497)
Authors:Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L.
Deposit date:2022-05-04
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway.
Structure, 30, 2022
4W97
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BU of 4w97 by Molmil
Structure of ketosteroid transcriptional regulator KstR2 of Mycobacterium tuberculosis
Descriptor: CHLORIDE ION, HTH-type transcriptional repressor KstR2, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-[(3aS,4S,7aS)-7a-methyl-1,5-bis(oxidanylidene)-2,3,3a,4,6,7-hexahydroinden-4-yl]propanethioate
Authors:Stogios, P.J, Evdokimova, E, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-08-27
Release date:2014-11-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator of Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
8C7U
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BU of 8c7u by Molmil
Transcriptional pleiotropic repressor CodY from Enterococcus faecalis in complex with Leu and a 30-bp DNA fragment encompassing two overlapping binding sites
Descriptor: DNA (29-MER), DNA (30-MER), GTP-sensing transcriptional pleiotropic repressor CodY, ...
Authors:Hainzl, T, Sauer-Eriksson, A.E.
Deposit date:2023-01-17
Release date:2023-06-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insights into CodY activation and DNA recognition.
Nucleic Acids Res., 51, 2023
8C7T
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BU of 8c7t by Molmil
Unliganded transcriptional pleiotropic repressor CodY from Enterococcus faecalis
Descriptor: GTP-sensing transcriptional pleiotropic repressor CodY
Authors:Hainzl, T, Sauer-Eriksson, A.E.
Deposit date:2023-01-17
Release date:2023-06-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural insights into CodY activation and DNA recognition.
Nucleic Acids Res., 51, 2023
6YS3
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BU of 6ys3 by Molmil
Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Schulte, L, Reitz, J, Kudlinzki, D, Hodirnau, V.V, Frangakis, A, Schwalbe, H.
Deposit date:2020-04-20
Release date:2020-09-30
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide
Nat Commun, 2020
6ZUI
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BU of 6zui by Molmil
Crystal structure of the Cys-Ser mutant of the cpYFP-based biosensor for hypochlorous acid
Descriptor: HTH-type transcriptional repressor NemR,Green fluorescent protein,Green fluorescent protein,HTH-type transcriptional repressor NemR
Authors:Tossounian, M.A, Van Molle, I, Messens, J.
Deposit date:2020-07-23
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.200082 Å)
Cite:Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives.
Nat Commun, 13, 2022
6O8M
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BU of 6o8m by Molmil
Crystal Structure of C9S apo Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulated bound to diamide (tetramethylazodicarboxamide).
Descriptor: N~1~,N~1~,N~2~,N~2~-tetramethylhydrazine-1,2-dicarboxamide, Transcriptional regulator, ArsR family
Authors:Capdevila, D.A, Gonzalez-Gutierrez, G, Giedroc, D.P.
Deposit date:2019-03-11
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural basis for persulfide-sensing specificity in a transcriptional regulator.
Nat.Chem.Biol., 17, 2021

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