8C7U

Transcriptional pleiotropic repressor CodY from Enterococcus faecalis in complex with Leu and a 30-bp DNA fragment encompassing two overlapping binding sites

Summary for 8C7U

Entry DOI	10.2210/pdb8c7u/pdb
Descriptor	GTP-sensing transcriptional pleiotropic repressor CodY, DNA (29-MER), DNA (30-MER), ... (5 entities in total)
Functional Keywords	leucine binding, pleiotropic transcription, regulator, transcription, dna complex
Biological source	Enterococcus faecalis (strain ATCC 700802 / V583) More
Total number of polymer chains	6
Total formula weight	135088.67
Authors	Hainzl, T.,Sauer-Eriksson, A.E. (deposition date: 2023-01-17, release date: 2023-06-28, Last modification date: 2023-11-15)
Primary citation	Hainzl, T.,Bonde, M.,Almqvist, F.,Johansson, J.,Sauer-Eriksson, A.E. Structural insights into CodY activation and DNA recognition. Nucleic Acids Res., 51:7631-7648, 2023 Cited by PubMed: 37326020 DOI: 10.1093/nar/gkad512 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.15 Å)

Structure validation