3MH6
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![BU of 3mh6 by Molmil](/molmil-images/mine/3mh6) | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | Descriptor: | DIISOPROPYL PHOSPHONATE, Protease do | Authors: | Krojer, T, Sawa, J, Huber, R, Clausen, T. | Deposit date: | 2010-04-07 | Release date: | 2010-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat.Struct.Mol.Biol., 17, 2010
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3MH7
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![BU of 3mh7 by Molmil](/molmil-images/mine/3mh7) | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | Descriptor: | 5-mer peptide, Protease do | Authors: | Krojer, T, Sawa, J, Huber, R, Clausen, T. | Deposit date: | 2010-04-07 | Release date: | 2010-06-30 | Last modified: | 2014-03-05 | Method: | X-RAY DIFFRACTION (2.961 Å) | Cite: | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat.Struct.Mol.Biol., 17, 2010
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3OU0
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![BU of 3ou0 by Molmil](/molmil-images/mine/3ou0) | re-refined 3CS0 | Descriptor: | Periplasmic serine endoprotease DegP, heptapeptide, pentapeptide | Authors: | Sauer, R.T, Grant, R.A, Kim, S. | Deposit date: | 2010-09-14 | Release date: | 2011-01-19 | Last modified: | 2012-02-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages. Cell(Cambridge,Mass.), 145, 2011
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1P1D
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![BU of 1p1d by Molmil](/molmil-images/mine/1p1d) | |
7YKF
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![BU of 7ykf by Molmil](/molmil-images/mine/7ykf) | Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex | Descriptor: | Ephexin4, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKI
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![BU of 7yki by Molmil](/molmil-images/mine/7yki) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR3 peptide | Descriptor: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKG
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![BU of 7ykg by Molmil](/molmil-images/mine/7ykg) | Crystal structure of MAGI2 PDZ0-GK/pSGEF complex | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, SGEF | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKH
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![BU of 7ykh by Molmil](/molmil-images/mine/7ykh) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR2 peptide | Descriptor: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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3SHW
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![BU of 3shw by Molmil](/molmil-images/mine/3shw) | Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide | Descriptor: | Gap junction gamma-1 protein, Tight junction protein ZO-1 | Authors: | Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M. | Deposit date: | 2011-06-17 | Release date: | 2011-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core To be Published
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3TMH
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![BU of 3tmh by Molmil](/molmil-images/mine/3tmh) | Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1 | Descriptor: | A-kinase anchor protein 10, mitochondrial, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, ... | Authors: | Sarma, G.N, Phan, R.H, Sankaran, B, Taylor, S.S. | Deposit date: | 2011-08-31 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure To be Published
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3TSZ
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3STJ
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![BU of 3stj by Molmil](/molmil-images/mine/3stj) | Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli | Descriptor: | Protease degQ, peptide (UNK) | Authors: | Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T. | Deposit date: | 2011-07-11 | Release date: | 2011-07-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope. J.Biol.Chem., 286, 2011
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3SUZ
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![BU of 3suz by Molmil](/molmil-images/mine/3suz) | Crystal structure of Rat Mint2 PPC | Descriptor: | Amyloid beta A4 precursor protein-binding family A member 2 | Authors: | Shen, Y, Long, J, Yan, X, Xie, X. | Deposit date: | 2011-07-11 | Release date: | 2012-07-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Open-closed motion of Mint2 regulates APP metabolism J Mol Cell Biol, 5, 2013
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3TSW
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![BU of 3tsw by Molmil](/molmil-images/mine/3tsw) | crystal structure of the PDZ3-SH3-GUK core module of Human ZO-1 | Descriptor: | SULFATE ION, Tight junction protein ZO-1 | Authors: | Nomme, J, Lavie, A. | Deposit date: | 2011-09-13 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.847 Å) | Cite: | The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1. J.Biol.Chem., 286, 2011
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3CS0
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![BU of 3cs0 by Molmil](/molmil-images/mine/3cs0) | Crystal structure of DegP24 | Descriptor: | Periplasmic serine endoprotease DegP, pentapeptide | Authors: | Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T. | Deposit date: | 2008-04-08 | Release date: | 2008-05-27 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the regulated protease and chaperone function of DegP Nature, 453, 2008
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4QL6
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![BU of 4ql6 by Molmil](/molmil-images/mine/4ql6) | Structure of C. trachomatis CT441 | Descriptor: | Carboxy-terminal processing protease | Authors: | Kohlmann, F, Hilgenfeld, R, Hansen, G. | Deposit date: | 2014-06-10 | Release date: | 2014-11-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Structural basis of the proteolytic and chaperone activity of Chlamydia trachomatis CT441 J.Bacteriol., 197, 2015
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4P2A
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![BU of 4p2a by Molmil](/molmil-images/mine/4p2a) | Structure of mouse VPS26A bound to rat SNX27 PDZ domain | Descriptor: | MERCURY (II) ION, Sorting nexin-27, Vacuolar protein sorting-associated protein 26A | Authors: | Clairfeuille, T, Gallon, M, Mas, C, Ghai, R, Teasdale, R, Cullen, P, Collins, B. | Deposit date: | 2014-03-03 | Release date: | 2014-09-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer. Proc.Natl.Acad.Sci.USA, 111, 2014
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4L8N
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1Z87
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![BU of 1z87 by Molmil](/molmil-images/mine/1z87) | solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin | Descriptor: | Alpha-1-syntrophin | Authors: | Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | Deposit date: | 2005-03-30 | Release date: | 2006-01-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin Embo J., 24, 2005
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2HGA
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![BU of 2hga by Molmil](/molmil-images/mine/2hga) | Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A | Descriptor: | Conserved protein MTH1368 | Authors: | Liu, G, Lin, Y, Parish, D, Shen, Y, Sukumaran, D, Yee, A, Semesi, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-26 | Release date: | 2006-07-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A TO BE PUBLISHED
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2KRG
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![BU of 2krg by Molmil](/molmil-images/mine/2krg) | Solution Structure of human sodium/ hydrogen exchange regulatory factor 1(150-358) | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | Authors: | Bhattacharya, S, Dai, Z, Li, J, Baxter, S, Callaway, D.J.E, Cowburn, D, Bu, Z. | Deposit date: | 2009-12-17 | Release date: | 2009-12-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation. J.Biol.Chem., 285, 2010
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5N7D
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![BU of 5n7d by Molmil](/molmil-images/mine/5n7d) | MAGI-1 complexed with a RSK1 peptide | Descriptor: | CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... | Authors: | Gogl, G, Nyitray, L. | Deposit date: | 2017-02-20 | Release date: | 2017-11-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
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8T1J
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![BU of 8t1j by Molmil](/molmil-images/mine/8t1j) | Uncrosslinked nNOS-CaM oxygenase homodimer | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ... | Authors: | Lee, K, Pospiech, T.H, Southworth, D. | Deposit date: | 2023-06-02 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry. J.Biol.Chem., 300, 2023
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8T1K
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![BU of 8t1k by Molmil](/molmil-images/mine/8t1k) | DSBU crosslinked nNOS-CaM oxygenase homodimer | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ... | Authors: | Lee, K, Pospiech, T.H, Southworth, D. | Deposit date: | 2023-06-02 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry. J.Biol.Chem., 300, 2023
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5MV8
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![BU of 5mv8 by Molmil](/molmil-images/mine/5mv8) | Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain | Descriptor: | GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... | Authors: | Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. | Deposit date: | 2017-01-16 | Release date: | 2017-07-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
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