4KMY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kmy by Molmil](/molmil-images/mine/4kmy) | Human folate receptor beta (FOLR2) at neutral pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Folate receptor beta, POTASSIUM ION | Authors: | Wibowo, A.S, Dann III, C.E. | Deposit date: | 2013-05-08 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.795 Å) | Cite: | Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
1DQ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dq8 by Molmil](/molmil-images/mine/1dq8) | COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG AND COA | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-HYDROXY-3-METHYL-GLUTARIC ACID, COENZYME A, ... | Authors: | Istvan, E.S, Palnitkar, M, Buchanan, S.K, Deisenhofer, J. | Deposit date: | 1999-12-30 | Release date: | 2000-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis. EMBO J., 19, 2000
|
|
1E0F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e0f by Molmil](/molmil-images/mine/1e0f) | Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor | Descriptor: | HAEMADIN, THROMBIN | Authors: | Richardson, J.L, Kroeger, B, Hoefken, W, Pereira, P, Huber, R, Bode, W, Fuentes-Prior, P. | Deposit date: | 2000-03-27 | Release date: | 2000-11-03 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor Embo J., 19, 2000
|
|
2F7D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f7d by Molmil](/molmil-images/mine/2f7d) | A mutant rabbit cathepsin K with a nitrile inhibitor | Descriptor: | (1R,2R)-N-(2-AMINOETHYL)-2-{[(4-METHOXYPHENYL)SULFONYL]METHYL}CYCLOHEXANECARBOXAMIDE, Cathepsin K | Authors: | Somoza, J.R. | Deposit date: | 2005-11-30 | Release date: | 2006-03-07 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K. J.Med.Chem., 49, 2006
|
|
1SPD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1spd by Molmil](/molmil-images/mine/1spd) | |
4HVS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hvs by Molmil](/molmil-images/mine/4hvs) | |
1DUY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1duy by Molmil](/molmil-images/mine/1duy) | CRYSTAL STRUCTURE OF HLA-A*0201/OCTAMERIC TAX PEPTIDE COMPLEX | Descriptor: | BETA-2 MICROGLOBULIN, HLA-A2*0201, HTLV-1 OCTAMERIC TAX PEPTIDE | Authors: | Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C. | Deposit date: | 2000-01-19 | Release date: | 2000-02-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site. J.Immunol., 164, 2000
|
|
2FJM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fjm by Molmil](/molmil-images/mine/2fjm) | The structure of phosphotyrosine phosphatase 1B in complex with compound 2 | Descriptor: | (4-{(2S,4E)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-2-[4-(METHOXYCARBONYL)PHENYL]-5-PHENYLPENT-4-ENYL}PHENYL)(DIFLUORO)METHYLPHOSPHONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Asante-Appiah, E, Patel, S, Desponts, C, Taylor, J.M, Lau, C, Dufresne, C, Therien, M, Friesen, R, Becker, J.W, Leblanc, Y, Scapin, G. | Deposit date: | 2006-01-03 | Release date: | 2006-01-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. J.Biol.Chem., 281, 2006
|
|
2EVW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2evw by Molmil](/molmil-images/mine/2evw) | |
1CIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cif by Molmil](/molmil-images/mine/1cif) | |
1CKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cko by Molmil](/molmil-images/mine/1cko) | |
4KMZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kmz by Molmil](/molmil-images/mine/4kmz) | Human folate receptor beta (FOLR2) in complex with the folate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FOLIC ACID, ... | Authors: | Wibowo, A.S, Dann III, C.E. | Deposit date: | 2013-05-08 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4KN2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kn2 by Molmil](/molmil-images/mine/4kn2) | Human folate receptor beta (FOLR2) in complex with antifolate pemetrexed | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, CHLORIDE ION, ... | Authors: | Wibowo, A.S, Dann III, C.E. | Deposit date: | 2013-05-08 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
1SEL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sel by Molmil](/molmil-images/mine/1sel) | |
1SUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sub by Molmil](/molmil-images/mine/1sub) | CALCIUM-INDEPENDENT SUBTILISIN BY DESIGN | Descriptor: | ACETONE, CALCIUM ION, POTASSIUM ION, ... | Authors: | Gallagher, T, Bryan, P, Gilliland, G.L. | Deposit date: | 1992-06-10 | Release date: | 1994-01-31 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Calcium-independent subtilisin by design. Proteins, 16, 1993
|
|
1DVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dvq by Molmil](/molmil-images/mine/1dvq) | CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN | Descriptor: | TRANSTHYRETIN | Authors: | Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C. | Deposit date: | 2000-01-22 | Release date: | 2001-01-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Rational design of potent human transthyretin amyloid disease inhibitors. Nat.Struct.Biol., 7, 2000
|
|
1DVS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dvs by Molmil](/molmil-images/mine/1dvs) | CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH RESVERATROL | Descriptor: | RESVERATROL, TRANSTHYRETIN | Authors: | Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C. | Deposit date: | 2000-01-22 | Release date: | 2001-01-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Rational design of potent human transthyretin amyloid disease inhibitors. Nat.Struct.Biol., 7, 2000
|
|
1SXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sxc by Molmil](/molmil-images/mine/1sxc) | CRYSTAL STRUCTURE OF REDUCED BOVINE ERYTHROCYTE SUPEROXIDE DISMUTASE AT 1.9 ANGSTROMS RESOLUTION | Descriptor: | COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION | Authors: | Rypniewski, W.R, Mangani, S, Bruni, B, Orioli, P, Casati, M, Wilson, K.S. | Deposit date: | 1995-03-17 | Release date: | 1995-06-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of reduced bovine erythrocyte superoxide dismutase at 1.9 A resolution. J.Mol.Biol., 251, 1995
|
|
1DRR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1drr by Molmil](/molmil-images/mine/1drr) | DNA/RNA HYBRID DUPLEX CONTAINING A PURINE-RICH DNA STRAND, NMR, 10 STRUCTURES | Descriptor: | DNA (5'-D(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3'), RNA (5'-R(*GP*CP*UP*UP*CP*UP*CP*UP*UP*C)-3') | Authors: | Gyi, J.I, Lane, A.N, Conn, G.L, Brown, T. | Deposit date: | 1997-10-21 | Release date: | 1998-04-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes. Biochemistry, 37, 1998
|
|
1T24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t24 by Molmil](/molmil-images/mine/1t24) | Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | Descriptor: | 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, GLYCEROL, L-lactate dehydrogenase, ... | Authors: | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | Deposit date: | 2004-04-20 | Release date: | 2004-05-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
|
|
1T32
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t32 by Molmil](/molmil-images/mine/1t32) | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | Descriptor: | 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, Cathepsin G, SULFATE ION | Authors: | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E. | Deposit date: | 2004-04-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
|
|
1DXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dxc by Molmil](/molmil-images/mine/1dxc) | CO complex of Myoglobin Mb-YQR at 100K | Descriptor: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Brunori, M, Vallone, B, Cutruzzola, F, Travaglini-Allocatelli, C, Berendzen, J, Chu, K, Sweet, R.M, Schlichting, I. | Deposit date: | 2000-01-03 | Release date: | 2000-04-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Role of Cavities in Protein Dynamics: Crystal Structure of a Novel Photolytic Intermediate of Myoglobin Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1DZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dzc by Molmil](/molmil-images/mine/1dzc) | High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures | Descriptor: | FIBROBLAST GROWTH FACTOR 1 | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | Deposit date: | 2000-02-24 | Release date: | 2000-03-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor Biochemistry, 39, 2000
|
|
1DZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dzd by Molmil](/molmil-images/mine/1dzd) | High resolution structure of acidic fibroblast growth factor (27-154), 24 NMR structures | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | Deposit date: | 2000-02-24 | Release date: | 2000-03-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor Biochemistry, 39, 2000
|
|
1VDV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vdv by Molmil](/molmil-images/mine/1vdv) | Bovine Milk Xanthine Dehydrogenase Y-700 Bound Form | Descriptor: | 1-[3-CYANO-4-(NEOPENTYLOXY)PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID, ACETIC ACID, CALCIUM ION, ... | Authors: | Fukunari, A, Okamoto, K, Nishino, T, Eger, B.T, Pai, E.F, Kamezawa, M, Yamada, I, Kato, N. | Deposit date: | 2004-03-25 | Release date: | 2004-12-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion J.Pharmacol.Exp.Ther., 311, 2004
|
|