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5OJ1	Penicillin Binding Protein 2x (PBP2x) from S.pneumoniae in complex with Oxacillin and a tetrasaccharide Descriptor: (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Penicillin-binding protein 2X, SODIUM ION Authors: Bernardo-Garcia, N, Hermoso, J.A. Deposit date: 2017-07-20 Release date: 2018-05-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae. ACS Chem. Biol., 13, 2018
1QME	PENICILLIN-BINDING PROTEIN 2X (PBP-2X) Descriptor: PENICILLIN-BINDING PROTEIN 2X, SULFATE ION Authors: Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. Deposit date: 1999-09-28 Release date: 2000-05-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance. J.Mol.Biol., 299, 2000
1QMF	PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX Descriptor: 2-[CARBOXY-(2-FURAN-2-YL-2-METHOXYIMINO-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, CEFUROXIME (OCT-3-ENE FORM), PENICILLIN-BINDING PROTEIN 2X Authors: Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. Deposit date: 1999-09-28 Release date: 2000-05-25 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance J.Mol.Biol., 299, 2000
1RP5	PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics Descriptor: SULFATE ION, penicillin-binding protein 2x Authors: Pernot, L, Chesnel, L, Legouellec, A, Croize, J, Vernet, T, Dideberg, O, Dessen, A. Deposit date: 2003-12-03 Release date: 2004-02-03 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics. J.Biol.Chem., 279, 2004
1PYY	Double mutant PBP2x T338A/M339F from Streptococcus pneumoniae strain R6 at 2.4 A resolution Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-O-octanoyl-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, Penicillin-binding protein 2X, ... Authors: Chesnel, L, Pernot, L, Lemaire, D, Champelovier, D, Croize, J, Dideberg, O, Vernet, T, Zapun, A. Deposit date: 2003-07-09 Release date: 2003-09-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.42 Å) Cite: The Structural Modifications Induced by the M339F Substitution in PBP2x from Streptococcus pneumoniae Further Decreases the Susceptibility to beta-Lactams of Resistant Strains J.Biol.Chem., 278, 2003
7O4A	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with piperacillin Descriptor: Hydrolyzed piperacillin, Penicillin-binding protein 1 Authors: Martinez Caballero, S, Hermoso, J.A. Deposit date: 2021-04-05 Release date: 2021-11-03 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.028 Å) Cite: Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7O49	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, CHLORIDE ION, ... Authors: Martinez Caballero, S, Hermoso, J.A. Deposit date: 2021-04-05 Release date: 2021-11-03 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7O4B	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with penicillin G Descriptor: CITRIC ACID, OPEN FORM - PENICILLIN G, Penicillin-binding protein 1, ... Authors: Martinez Caballero, S, Hermoso, J.A. Deposit date: 2021-04-05 Release date: 2021-11-03 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.593 Å) Cite: Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7OK9	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with pentaglycine Descriptor: CADMIUM ION, CHLORIDE ION, Penicillin-binding protein 1, ... Authors: Martinez Caballero, S, Hermoso, J.A. Deposit date: 2021-05-17 Release date: 2021-11-03 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.36 Å) Cite: Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021

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