7O4B

Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with penicillin G

Summary for 7O4B

• Entry DOI: 10.2210/pdb7o4b/pdb
• Descriptor: Penicillin-binding protein 1, CITRIC ACID, SULFATE ION, ... (5 entities in total)
• Functional Keywords: cell division, antibiotic resistance, peptidoglycan synthesis, transpeptidase, hydrolase
• Biological source: Staphylococcus aureus subsp. aureus COL; More
• Total number of polymer chains: 2
• Total formula weight: 147021.91

Authors

Martinez Caballero, S.,Hermoso, J.A. (deposition date: 2021-04-05, release date: 2021-11-03, Last modification date: 2024-01-31)

• Primary citation: Martinez-Caballero, S.,Mahasenan, K.V.,Kim, C.,Molina, R.,Feltzer, R.,Lee, M.,Bouley, R.,Hesek, D.,Fisher, J.F.,Munoz, I.G.,Chang, M.,Mobashery, S.,Hermoso, J.A.; Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery.; Comput Struct Biotechnol J, 19:5392-5405, 2021; PubMed: 34667534; DOI: 10.1016/j.csbj.2021.09.018

Experimental method

X-RAY DIFFRACTION (2.593 Å)