7O49

Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus

Summary for 7O49

Entry DOI	10.2210/pdb7o49/pdb
Descriptor	Penicillin-binding protein 1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, ... (5 entities in total)
Functional Keywords	cell division, antibiotic resistance, peptidoglycan synthesis, transpeptidase, hydrolase
Biological source	Staphylococcus aureus subsp. aureus COL
Total number of polymer chains	12
Total formula weight	872086.98
Authors	Martinez Caballero, S.,Hermoso, J.A. (deposition date: 2021-04-05, release date: 2021-11-03, Last modification date: 2024-01-31)
Primary citation	Martinez-Caballero, S.,Mahasenan, K.V.,Kim, C.,Molina, R.,Feltzer, R.,Lee, M.,Bouley, R.,Hesek, D.,Fisher, J.F.,Munoz, I.G.,Chang, M.,Mobashery, S.,Hermoso, J.A. Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19:5392-5405, 2021 Cited by PubMed: 34667534 DOI: 10.1016/j.csbj.2021.09.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.03 Å)

Structure validation