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1PLR
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CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
Authors:Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J.
Deposit date:1995-01-02
Release date:1995-03-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
2NTI
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BU of 2nti by Molmil
Crystal structure of PCNA123 heterotrimer.
Descriptor: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ...
Authors:Hlinkova, V, Ling, H.
Deposit date:2006-11-07
Release date:2007-12-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
8COB
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BU of 8cob by Molmil
Crystal structure of human PCNA in complex with ERCC6L2 PIP box peptide
Descriptor: DNA excision repair protein ERCC-6-like 2, Proliferating cell nuclear antigen
Authors:Ariza, A.
Deposit date:2023-02-27
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:ERCC6L2 mitigates replication stress and promotes centromere stability.
Cell Rep, 42, 2023
4CS5
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BU of 4cs5 by Molmil
Crystal Structure of PCNA from Litopenaeus vannamei
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R.
Deposit date:2014-03-04
Release date:2014-04-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box.
Plos One, 9, 2014
4D2G
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BU of 4d2g by Molmil
Crystal structure of human PCNA in complex with p15 peptide
Descriptor: P15, PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J.
Deposit date:2014-05-09
Release date:2015-03-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
5E0T
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BU of 5e0t by Molmil
Human PCNA mutant - S228I
Descriptor: Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6653 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
1W60
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NATIVE HUMAN PCNA
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.
Deposit date:2004-08-11
Release date:2005-01-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
1IZ4
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Pyrococcus furiosus PCNA mutant (Met73Leu/Asp143Ala): tetragonal form
Descriptor: Proliferating cell nuclear antigen
Authors:Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
Deposit date:2002-09-21
Release date:2003-04-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
PROTEIN SCI., 12, 2003
1VYM
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BU of 1vym by Molmil
NATIVE HUMAN PCNA
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.
Deposit date:2004-05-03
Release date:2005-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
1VYJ
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BU of 1vyj by Molmil
Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK
Authors:Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.D.
Deposit date:2004-04-30
Release date:2005-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
5YD8
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BU of 5yd8 by Molmil
Crystal structure of human PCNA in complex with APIM of human ZRANB3
Descriptor: Proliferating cell nuclear antigen, ZRANB3
Authors:Hashimoto, H, Tagata, R.
Deposit date:2017-09-12
Release date:2018-04-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of proliferating cell nuclear antigen (PCNA) bound to an APIM peptide reveals the universality of PCNA interaction.
Acta Crystallogr.,Sect.F, 74, 2018
5YCO
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BU of 5yco by Molmil
Complex structure of PCNA with UHRF2
Descriptor: E3 ubiquitin-protein ligase UHRF2, GLYCEROL, Proliferating cell nuclear antigen, ...
Authors:Wu, M, Chen, W, Hang, T, Wang, C, Zhang, X, Zang, J.
Deposit date:2017-09-07
Release date:2017-11-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA.
Biochem. Biophys. Res. Commun., 494, 2017
6WAC
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BU of 6wac by Molmil
FF248-249AA PCNA mutant defective in BIR
Descriptor: Proliferating cell nuclear antigen
Authors:Ripley, B.M, Washington, M.T.
Deposit date:2020-03-25
Release date:2020-09-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
6QC0
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BU of 6qc0 by Molmil
PCNA complex with Cdt2 C-terminal PIP-box peptide
Descriptor: Denticleless protein homolog, Proliferating cell nuclear antigen
Authors:Perrakis, A.P, von Castelmur, E.
Deposit date:2018-12-25
Release date:2019-01-23
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018
6QCG
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BU of 6qcg by Molmil
PCNA complex with Cdt1 N-terminal PIP-box peptide
Descriptor: DNA replication factor Cdt1, Proliferating cell nuclear antigen
Authors:Perrakis, A, von Castelmur, E.
Deposit date:2018-12-28
Release date:2019-01-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018
5H0T
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BU of 5h0t by Molmil
Crystal structure of proliferating cell nuclear antigen from Leishmania donovani at 2.73 Angstrom resolution
Descriptor: DI(HYDROXYETHYL)ETHER, Proliferating cell nuclear antigen
Authors:Singh, P.K, Yadav, S.P, Sharma, P.S, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2016-10-06
Release date:2016-11-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani.
Biochim. Biophys. Acta, 1865, 2017
6QH1
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BU of 6qh1 by Molmil
The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide
Descriptor: Proliferating cell nuclear antigen, S-phase delaying protein 1
Authors:Kragelund, B.B, Nielsen, O, Olsen, J.G, Kassem, N, Prestel, A.
Deposit date:2019-01-14
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide
To Be Published
6W9W
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BU of 6w9w by Molmil
R80A PCNA mutant defective in BIR
Descriptor: Proliferating cell nuclear antigen
Authors:Ripley, B.M, Washington, M.T.
Deposit date:2020-03-23
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
6VVO
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BU of 6vvo by Molmil
Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A.
Deposit date:2020-02-18
Release date:2020-02-26
Last modified:2020-03-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism
Biorxiv, 2020
5HAC
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BU of 5hac by Molmil
Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution
Descriptor: Proliferating cell nuclear antigen
Authors:Singh, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2015-12-30
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution
To Be Published
5ZUT
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BU of 5zut by Molmil
Crystal Structure of Yeast PCNA in Complex with N24 Peptide
Descriptor: N24, Proliferating cell nuclear antigen
Authors:Cheng, X.Y, Kuang, X.L, Zhou, Y, Xia, X.M, SU, Z.D.
Deposit date:2018-05-08
Release date:2018-05-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Crystal Structure of Yeast PCNA in Complex with N24 Peptide
To Be Published
1ISQ
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BU of 1isq by Molmil
Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide
Descriptor: Proliferating Cell Nuclear Antigen, replication factor C large subunit
Authors:Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
Deposit date:2001-12-19
Release date:2002-10-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus
Genes Cells, 7, 2002
1IZ5
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BU of 1iz5 by Molmil
Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form
Descriptor: Proliferating cell nuclear antigen
Authors:Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
Deposit date:2002-09-23
Release date:2003-04-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
PROTEIN SCI., 12, 2003
5MLW
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BU of 5mlw by Molmil
Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide
Descriptor: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION
Authors:Ariza, A.
Deposit date:2016-12-07
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
5MAV
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BU of 5mav by Molmil
Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide.
Descriptor: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen
Authors:Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
Deposit date:2016-11-06
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.575 Å)
Cite:A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Nucleic Acids Res., 45, 2017

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