6VVO

Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA)

Summary for 6VVO

• Entry DOI: 10.2210/pdb6vvo/pdb
• EMDB information: 21405
• Descriptor: Replication factor C subunit 1, Replication factor C subunit 2, Replication factor C subunit 5, ... (9 entities in total)
• Functional Keywords: sliding clamp, dna replication, aaa+, atpase, clamp loader, dna binding protein, replication
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 313340.61

Authors

Gaubitz, C.,Liu, X.,Stone, N.P.,Kelch, B.A. (deposition date: 2020-02-18, release date: 2020-02-26, Last modification date: 2020-03-25)

• Primary citation: Gaubitz, C.,Liu, X.,Magrino, J.,Stone, N.P.,Landeck, J.,Hedglin, M.,Kelch, B.A.; Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism; Biorxiv, 2020; DOI: 10.1101/2020.02.18.953257

Experimental method

ELECTRON MICROSCOPY (3.4 Å)