PDB: 224931 resultsInfo pagesStatus searchChemie searchBIRD

---

2PUU	Crystal structure of p38 complex with 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(6-morpholin-4-ylmethyl-pyridin-3-yl)naphthalen-1-yl]urea Descriptor: 5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-{[({4-[6-(MORPHOLIN-4-YLMETHYL)PYRIDIN-3-YL]-1-NAPHTHYL}AMINO)CARBONYL]AMINO}-1H-PYRAZOL-2-IUM, Mitogen-activated protein kinase 14 Authors: Qian, K.C. Deposit date: 2007-05-09 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A new class of p38 MAP kinase inhibitors based on the pyrazole-naphthyl urea scaffold To be Published
2PUV	The crystal structure of isomerase domain of glucosamine-6-phosphate synthase from Candida albicans Descriptor: 5-AMINO-5-DEOXY-1-O-PHOSPHONO-D-MANNITOL, ACETATE ION, SODIUM ION, ... Authors: Raczynska, J, Olchowy, J, Milewski, S, Rypniewski, W. Deposit date: 2007-05-09 Release date: 2007-09-11 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Crystal and Solution Studies of Glucosamine-6-phosphate Synthase from Candida albicans J.Mol.Biol., 372, 2007
2PUW	The crystal structure of isomerase domain of glucosamine-6-phosphate synthase from Candida albicans Descriptor: 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, isomerase domain of glutamine-fructose-6-phosphate transaminase (isomerizing) Authors: Raczynska, J, Olchowy, J, Milewski, S, Rypniewski, W. Deposit date: 2007-05-09 Release date: 2007-09-11 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.151 Å) Cite: The Crystal and Solution Studies of Glucosamine-6-phosphate Synthase from Candida albicans J.Mol.Biol., 372, 2007
2PUX	Crystal structure of murine thrombin in complex with the extracellular fragment of murine PAR3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 3, Thrombin heavy chain, ... Authors: Bah, A, Chen, Z, Bush-Pelc, L.A, Mathews, F.S, Di Cera, E. Deposit date: 2007-05-09 Release date: 2007-07-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4. Proc.Natl.Acad.Sci.Usa, 104, 2007
2PUY	Crystal Structure of the BHC80 PHD finger Descriptor: Histone H3, PHD finger protein 21A, ZINC ION Authors: Horton, J.R, Cheng, X, Collins, R.E. Deposit date: 2007-05-09 Release date: 2007-08-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature, 448, 2007
2PUZ	Crystal structure of Imidazolonepropionase from Agrobacterium tumefaciens with bound product N-formimino-L-Glutamate Descriptor: CHLORIDE ION, FE (III) ION, Imidazolonepropionase, ... Authors: Tyagi, R, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2007-05-09 Release date: 2007-05-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.83 Å) Cite: X-ray structure of imidazolonepropionase from Agrobacterium tumefaciens at 1.87 A resolution. Proteins, 69, 2007
2PV0	DNA methyltransferase 3 like protein (DNMT3L) Descriptor: DNA (cytosine-5)-methyltransferase 3-like, ZINC ION Authors: Cheng, X. Deposit date: 2007-05-09 Release date: 2007-08-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.3 Å) Cite: DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature, 448, 2007
2PV1	Crystallographic Structure of SurA first peptidyl-prolyl isomerase domain complexed with peptide WEYIPNV Descriptor: Chaperone surA, Glycosyl transferase, group 1 Authors: Xu, X, McKay, D.B. Deposit date: 2007-05-09 Release date: 2007-10-02 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The Periplasmic Bacterial Molecular Chaperone SurA Adapts its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues. J.Mol.Biol., 373, 2007
2PV2	Crystallographic Structure of SurA first peptidyl-prolyl isomerase domain complexed with peptide NFTLKFWDIFRK Descriptor: C-peptide, Chaperone surA Authors: Xu, X, McKay, D.B. Deposit date: 2007-05-09 Release date: 2007-10-02 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The Periplasmic Bacterial Molecular Chaperone SurA Adapts its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues. J.Mol.Biol., 373, 2007
2PV3	Crystallographic Structure of SurA fragment lacking the second peptidyl-prolyl isomerase domain complexed with peptide NFTLKFWDIFRK Descriptor: C-peptide, Chaperone surA Authors: Xu, X, McKay, D.B. Deposit date: 2007-05-09 Release date: 2007-10-02 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.39 Å) Cite: The Periplasmic Bacterial Molecular Chaperone SurA Adapts its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues. J.Mol.Biol., 373, 2007
2PV4	CRYSTAL STRUCTURE OF AN UNCHARACTERIZED PROTEIN FROM DUF3069 FAMILY (SAMA_2622) FROM SHEWANELLA AMAZONENSIS SB2B AT 1.95 A RESOLUTION Descriptor: GLYCEROL, Uncharacterized protein Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2007-05-09 Release date: 2007-05-22 Last modified: 2023-01-25 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of uncharacterized protein (YP_928494.1) from Shewanella amazonensis SB2B at 1.95 A resolution To be published
2PV6	HIV-1 gp41 Membrane Proximal Ectodomain Region peptide in DPC micelle Descriptor: Envelope glycoprotein Authors: Sun, Z.-Y.J, Oh, K.J, Kim, M, Reinherz, E.L, Wagner, G. Deposit date: 2007-05-09 Release date: 2008-03-18 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane Immunity, 28, 2008
2PV7	Crystal structure of chorismate mutase / prephenate dehydrogenase (tyrA) (1574749) from Haemophilus influenzae RD at 2.00 A resolution Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, T-protein [Includes: Chorismate mutase (EC 5.4.99.5) (CM) and Prephenate dehydrogenase (EC 1.3.1.12) (PDH)], TYROSINE Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2007-05-09 Release date: 2007-05-22 Last modified: 2023-01-25 Method: X-RAY DIFFRACTION (2 Å) Cite: The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes. Acta Crystallogr.,Sect.F, 66, 2010
2PV9	Crystal structure of murine thrombin in complex with the extracellular fragment of murine PAR4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 4, Thrombin heavy chain, ... Authors: Bah, A, Chen, Z, Bush-Pelc, L.A, Mathews, F.S, Di Cera, E. Deposit date: 2007-05-09 Release date: 2007-07-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4. Proc.Natl.Acad.Sci.Usa, 104, 2007
2PVA	OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS Descriptor: DITHIANE DIOL, PENICILLIN V ACYLASE Authors: Suresh, C.G, Pundle, A.V, Rao, K.N, SivaRaman, H, Brannigan, J.A, McVey, C.E, Verma, C.S, Dauter, Z, Dodson, E.J, Dodson, G.G. Deposit date: 1998-11-13 Release date: 2000-07-26 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members. Nat.Struct.Biol., 6, 1999
2PVB	PIKE PARVALBUMIN (PI 4.10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0.91 A). Descriptor: AMMONIUM ION, CALCIUM ION, FORMIC ACID, ... Authors: Declercq, J.P, Evrard, C. Deposit date: 1998-10-02 Release date: 1998-10-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (0.91 Å) Cite: Crystal structure of the EF-hand parvalbumin at atomic resolution (0.91 A) and at low temperature (100 K). Evidence for conformational multistates within the hydrophobic core. Protein Sci., 8, 1999
2PVC	DNMT3L recognizes unmethylated histone H3 lysine 4 Descriptor: DNA (cytosine-5)-methyltransferase 3-like, Histone H3 peptide, ZINC ION Authors: Cheng, X. Deposit date: 2007-05-09 Release date: 2007-08-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.69 Å) Cite: DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature, 448, 2007
2PVD	Crystal srtucture of the reduced ferredoxin:thioredoxin reductase Descriptor: Ferredoxin-thioredoxin reductase, catalytic chain, variable chain, ... Authors: Dai, S. Deposit date: 2007-05-09 Release date: 2007-07-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase. Nature, 448, 2007
2PVE	NMR and X-ray Analysis of Structural Additivity in Metal Binding Site-Swapped Hybrids of Rubredoxin Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Rubredoxin, ... Authors: LeMaster, D.M, Anderson, J.S, Wang, L, Guo, Y, Li, H, Hernandez, G. Deposit date: 2007-05-09 Release date: 2007-12-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (0.79 Å) Cite: NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin. Bmc Struct.Biol., 7, 2007
2PVF	Crystal Structure of Tyrosine Phosphorylated Activated FGF Receptor 2 (FGFR2) Kinase Domain in Complex with ATP Analog and Substrate Peptide Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-09 Release date: 2007-09-25 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PVG	Crystal srtucture of the binary complex between ferredoxin and ferredoxin:thioredoxin reductase Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, Ferredoxin-thioredoxin reductase, ... Authors: Dai, S. Deposit date: 2007-05-09 Release date: 2007-07-10 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase. Nature, 448, 2007
2PVH	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 Descriptor: Casein kinase II subunit alpha, N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE Authors: Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. Deposit date: 2007-05-09 Release date: 2008-05-13 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVI	PVUII ENDONUCLEASE COMPLEXED TO AN IODINATED COGNATE DNA Descriptor: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*(C38)P*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII Authors: Horton, J, Cheng, X. Deposit date: 1998-11-01 Release date: 1999-12-20 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.76 Å) Cite: How is modification of the DNA substrate recognized by the PvuII restriction endonuclease? J.Biol.Chem., 379, 1998
2PVJ	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 Descriptor: 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha Authors: Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. Deposit date: 2007-05-09 Release date: 2008-05-13 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVK	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 Descriptor: 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha Authors: Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. Deposit date: 2007-05-09 Release date: 2008-05-13 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007

<1934193519361937193819391940194119421943194419451946194719481949>