2PVC
DNMT3L recognizes unmethylated histone H3 lysine 4
Summary for 2PVC
Entry DOI | 10.2210/pdb2pvc/pdb |
Related | 2PV0 |
Descriptor | DNA (cytosine-5)-methyltransferase 3-like, Histone H3 peptide, ZINC ION (3 entities in total) |
Functional Keywords | dnmt3l, unmethylated h3k4, de novo dna methylation, transferase regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): Q9UJW3 |
Total number of polymer chains | 6 |
Total formula weight | 133511.26 |
Authors | Cheng, X. (deposition date: 2007-05-09, release date: 2007-08-14, Last modification date: 2023-08-30) |
Primary citation | Ooi, S.K.,Qiu, C.,Bernstein, E.,Li, K.,Jia, D.,Yang, Z.,Erdjument-Bromage, H.,Tempst, P.,Lin, S.P.,Allis, C.D.,Cheng, X.,Bestor, T.H. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature, 448:714-717, 2007 Cited by PubMed: 17687327DOI: 10.1038/nature05987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.69 Å) |
Structure validation
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