2PVC

DNMT3L recognizes unmethylated histone H3 lysine 4

Summary for 2PVC

• Entry DOI: 10.2210/pdb2pvc/pdb
• Related: 2PV0
• Descriptor: DNA (cytosine-5)-methyltransferase 3-like, Histone H3 peptide, ZINC ION (3 entities in total)
• Functional Keywords: dnmt3l, unmethylated h3k4, de novo dna methylation, transferase regulator
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus (Probable): Q9UJW3
• Total number of polymer chains: 6
• Total formula weight: 133511.26

Authors

Cheng, X. (deposition date: 2007-05-09, release date: 2007-08-14, Last modification date: 2023-08-30)

• Primary citation: Ooi, S.K.,Qiu, C.,Bernstein, E.,Li, K.,Jia, D.,Yang, Z.,Erdjument-Bromage, H.,Tempst, P.,Lin, S.P.,Allis, C.D.,Cheng, X.,Bestor, T.H.; DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.; Nature, 448:714-717, 2007; PubMed: 17687327; DOI: 10.1038/nature05987

Experimental method

X-RAY DIFFRACTION (3.69 Å)