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6U6I
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NTD of GluA2 in complex with CNIH3 - with antagonist ZK200775 - in asymmetric global conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2019-08-29
Release date:2019-12-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6UD4
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BU of 6ud4 by Molmil
GluA2 in complex with its auxiliary subunit CNIH3 in AS map II - (LBD-TMD-C3(AS) II)- with antagonist ZK200775, without NTD
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2019-09-18
Release date:2019-12-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6USV
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BU of 6usv by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and SDZ 220-040
Descriptor: (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, GLYCEROL, GLYCINE, ...
Authors:Romero-Hernandez, A, Tajima, N, Chou, T, Furukawa, h.
Deposit date:2019-10-28
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6USU
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BU of 6usu by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with L689,560 and glutamate
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ...
Authors:Romero-Hernandez, A, Tajima, N, Chou, T, Furukawa, H.
Deposit date:2019-10-28
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6UZ6
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BU of 6uz6 by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and glutamate
Descriptor: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-14
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6UZX
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BU of 6uzx by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and UBP791
Descriptor: (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCEROL, GLYCINE, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-15
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6UZG
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BU of 6uzg by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and homoquinolinic acid
Descriptor: 3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-15
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6VEA
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BU of 6vea by Molmil
Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain in complex with Glycine
Descriptor: BETA-MERCAPTOETHANOL, GLYCINE, Glutamate receptor 3.2, ...
Authors:Gangwar, S.P, Green, M.N, Yoder, J.B, Sobolevsky, A.I.
Deposit date:2019-12-30
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain.
Structure, 29, 2021
6UZR
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BU of 6uzr by Molmil
Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and homoquinolinic acid
Descriptor: 3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCEROL, GLYCINE, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-15
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6VE8
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BU of 6ve8 by Molmil
Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain in complex with Methionine
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ...
Authors:Gangwar, S.P, Green, M.N, Yoder, J.B, Sobolevsky, A.I.
Deposit date:2019-12-30
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain.
Structure, 29, 2021
6UZW
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BU of 6uzw by Molmil
Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and UBP791
Descriptor: (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-15
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6WHS
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BU of 6whs by Molmil
GluN1b-GluN2B NMDA receptor in non-active 1 conformation at 3.95 angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHV
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BU of 6whv by Molmil
GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 2
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WI1
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BU of 6wi1 by Molmil
GluN1b-GluN2B NMDA receptor in active conformation stabilized by inter-GluN1b-GluN2B subunit cross-linking
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHR
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BU of 6whr by Molmil
GluN1b-GluN2B NMDA receptor in non-active 2 conformation at 4 angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHT
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BU of 6wht by Molmil
GluN1b-GluN2B NMDA receptor in active conformation at 4.4 angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WI0
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BU of 6wi0 by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 2
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHX
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BU of 6whx by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 2
Descriptor: (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.09 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHW
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BU of 6whw by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 1
Descriptor: (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.09 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHU
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BU of 6whu by Molmil
GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 1
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHY
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BU of 6why by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 1
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
3EN3
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BU of 3en3 by Molmil
Crystal Structure of the GluR4 Ligand-Binding domain in complex with kainate
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 4,Glutamate receptor
Authors:Gill, A, Madden, D.R.
Deposit date:2008-09-25
Release date:2009-05-19
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
Biochemistry, 47, 2008
3EPE
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BU of 3epe by Molmil
Crystal Structure of the GluR4 Ligand-Binding domain in complex with glutamate
Descriptor: GLUTAMIC ACID, Glutamate receptor 4,Glutamate receptor
Authors:Gill, A, Madden, D.R.
Deposit date:2008-09-29
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
Biochemistry, 47, 2008
3FAS
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BU of 3fas by Molmil
X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-glutamate at 1.40A resolution
Descriptor: GLUTAMIC ACID, GLYCEROL, Glutamate receptor 4, ...
Authors:Kasper, C, Frydenvang, K, Naur, P, Gajhede, M, Kastrup, J.S.
Deposit date:2008-11-18
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4
Febs Lett., 582, 2008
3FAT
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BU of 3fat by Molmil
X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at 1.90A resolution
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, ACETIC ACID, GLYCEROL, ...
Authors:Kasper, C, Frydenvang, K, Naur, P, Gajhede, M, Kastrup, J.S.
Deposit date:2008-11-18
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4
Febs Lett., 582, 2008

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