6WHW
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 1
Summary for 6WHW
Entry DOI | 10.2210/pdb6whw/pdb |
EMDB information | 21678 |
Descriptor | Ionotropic glutamate receptor , NMDA receptor GluN1b, Ionotropic glutamate receptor , NMDA receptor GluN2B, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, ... (4 entities in total) |
Functional Keywords | nmdars, ligand-gated ion channels, metal transport, ionotropic glutamate receptor, membrane protein, glun2b antagonist |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 4 |
Total formula weight | 415145.76 |
Authors | Chou, T.,Tajima, N.,Furukawa, H. (deposition date: 2020-04-08, release date: 2020-07-15, Last modification date: 2020-08-05) |
Primary citation | Chou, T.H.,Tajima, N.,Romero-Hernandez, A.,Furukawa, H. Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182:357-371.e13, 2020 Cited by PubMed: 32610085DOI: 10.1016/j.cell.2020.05.052 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.09 Å) |
Structure validation
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