6U6I

NTD of GluA2 in complex with CNIH3 - with antagonist ZK200775 - in asymmetric global conformation

Summary for 6U6I

Entry DOI	10.2210/pdb6u6i/pdb
EMDB information	20330 20654 20666
Descriptor	Glutamate receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	ionotropic glutamate receptor, ampa receptor, cornichon, auxiliary subunit, ion channel, ligand gated ion channel, synaptic transmission, excitatory synaptic transmission, neurotransmitter receptor, stargazin, tarp, zk200775, lipid, mpqx, transport protein
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	4
Total formula weight	400364.66
Authors	Nakagawa, T. (deposition date: 2019-08-29, release date: 2019-12-04, Last modification date: 2020-07-29)
Primary citation	Nakagawa, T. Structures of the AMPA receptor in complex with its auxiliary subunit cornichon. Science, 366:1259-1263, 2019 Cited by PubMed: 31806817 DOI: 10.1126/science.aay2783 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.12 Å)

Structure validation