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3RGE	Crystal structure of the W5H mutant of human carbonic anhydrase II Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Domsic, J.F, Robbins, A.H, McKenna, R. Deposit date: 2011-04-08 Release date: 2012-02-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.096 Å) Cite: Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch.Biochem.Biophys., 516, 2011
1FSR	X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT Descriptor: CARBONIC ANHYDRASE II, COPPER (II) ION Authors: Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W. Deposit date: 2000-09-11 Release date: 2001-01-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II. Biochemistry, 39, 2000
3RG3	Crystal structure of the W5E mutant of human carbonic anhydrase II Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Domsic, J.F, Robbins, A.H, McKenna, R. Deposit date: 2011-04-07 Release date: 2012-02-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.903 Å) Cite: Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch.Biochem.Biophys., 516, 2011
1FSN	X-RAY CRYSTAL STRUCTURE OF METAL-FREE F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT Descriptor: CARBONIC ANHYDRASE II Authors: Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W. Deposit date: 2000-09-11 Release date: 2001-01-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II. Biochemistry, 39, 2000
1FSQ	X-RAY CRYSTAL STRUCTURE OF COBALT-BOUND F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT Descriptor: CARBONIC ANHYDRASE II, COBALT (II) ION Authors: Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W. Deposit date: 2000-09-11 Release date: 2001-01-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II. Biochemistry, 39, 2000
3RG4	Crystal structure of the W5F mutant of human carbonic anhydrase II Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Domsic, J.F, Robbins, A.H, McKenna, R. Deposit date: 2011-04-07 Release date: 2012-02-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch.Biochem.Biophys., 516, 2011
3P58	Human Carbonic Anhydrase in complex with Benzyl (Methyl) Carbamodithoic Acid Descriptor: Carbonic anhydrase 2, ZINC ION, benzyl(methyl)carbamodithioic acid Authors: Aggarwal, M, McKenna, R. Deposit date: 2010-10-08 Release date: 2011-10-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Chem.Commun.(Camb.), 48, 2012
3T84	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates Descriptor: 4-O-acetyl-6-O-sulfamoyl-alpha-D-galactopyranose, Carbonic anhydrase 2, ZINC ION Authors: Hofmann, A, Wang, C.K. Deposit date: 2011-08-01 Release date: 2011-10-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
3T85	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates Descriptor: 3,4-di-O-acetyl-6-O-sulfamoyl-alpha-D-mannopyranose, Carbonic anhydrase 2, ZINC ION Authors: Hofmann, A, Wang, C.K. Deposit date: 2011-08-01 Release date: 2011-10-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
3T83	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates Descriptor: 2,3,4-tri-O-propanoyl-6-O-sulfamoyl-alpha-D-glucopyranose, 2,3,4-tri-O-propanoyl-6-O-sulfamoyl-beta-D-glucopyranose, Carbonic anhydrase 2, ... Authors: Hofmann, A, Wang, C.K. Deposit date: 2011-08-01 Release date: 2011-10-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
3MWO	Human carbonic anhydrase II in a doubled monoclinic cell: a re-determination Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Robbins, A.H, McKenna, R. Deposit date: 2010-05-06 Release date: 2010-06-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinic P2(1) with a doubled a axis. Acta Crystallogr.,Sect.D, 66, 2010
3TVO	Human Carbonic Anhydrase II Proton Transfer Double Mutant Descriptor: Carbonic anhydrase 2, GLYCEROL, ZINC ION Authors: Mikulski, R.M. Deposit date: 2011-09-20 Release date: 2012-08-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Water Networks in Fast Proton Transfer during Catalysis by Human Carbonic Anhydrase II. Biochemistry, 52, 2013
3TVN	Human Carbonic Anhydrase II Proton Transfer Mutant Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Mikulski, R.L, West, D.M, Sippel, K.H, Avvaru, B.S, Chingkuang, T, McKenna, R. Deposit date: 2011-09-20 Release date: 2012-08-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.497 Å) Cite: Water Networks in Fast Proton Transfer during Catalysis by Human Carbonic Anhydrase II. Biochemistry, 52, 2013
3T82	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates Descriptor: 3,4-di-O-acetyl-6-O-sulfamoyl-alpha-D-glucopyranose, Carbonic anhydrase 2, ZINC ION Authors: Hofmann, A, Wang, C.K. Deposit date: 2011-08-01 Release date: 2011-10-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.002 Å) Cite: Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
1I9M	CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(2,4-DIFLUOROPHENYL)METHYL]-BENZAMIDE Descriptor: 4-(AMINOSULFONYL)-N-[(2,4-DIFLUOROPHENYL)METHYL]-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Kim, C.-Y, Chandra, P.P, Jain, A, Christianson, D.W. Deposit date: 2001-03-20 Release date: 2001-03-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II. J.Am.Chem.Soc., 123, 2001
1I9N	CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(2,5-DIFLUOROPHENYL)METHYL]-BENZAMIDE Descriptor: 4-(AMINOSULFONYL)-N-[(2,5-DIFLUOROPHENYL)METHYL]-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Kim, C.-Y, Chandra, P.P, Jain, A, Christianson, D.W. Deposit date: 2001-03-20 Release date: 2001-03-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II. J.Am.Chem.Soc., 123, 2001
1I9P	CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(2,4,6-TRIFLUOROPHENYL)METHYL]-BENZAMIDE Descriptor: 4-(AMINOSULFONYL)-N-[(2,4,6-TRIFLUOROPHENYL)METHYL]-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Kim, C.-Y, Chandra, P.P, Jain, A, Christianson, D.W. Deposit date: 2001-03-20 Release date: 2001-03-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II. J.Am.Chem.Soc., 123, 2001
1I9Q	CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL]-BENZAMIDE Descriptor: 4-(AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL]-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Kim, C.-Y, Chandra, P.P, Jain, A, Christianson, D.W. Deposit date: 2001-03-20 Release date: 2001-03-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II. J.Am.Chem.Soc., 123, 2001
1I9L	CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(4-FLUOROPHENYL)METHYL]-BENZAMIDE Descriptor: 4-(AMINOSULFONYL)-N-[(4-FLUOROPHENYL)METHYL]-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Kim, C.-Y, Chandra, P.P, Jain, A, Christianson, D.W. Deposit date: 2001-03-20 Release date: 2001-03-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II. J.Am.Chem.Soc., 123, 2001
4QK2	Structural and Catalytic Effects of Proline Substitution and Surface Loop Deletion in the Extended Active Site of Human Carbonic Anhydrase II - E234P Descriptor: Carbonic anhydrase 2, GLYCEROL, ZINC ION Authors: Boone, C.D, Rasi, V, McKenna, R. Deposit date: 2014-06-05 Release date: 2015-03-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.519 Å) Cite: Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II. Febs J., 282, 2015
4QK1	Structural and Catalytic Effects of Proline Substitution and Surface Loop Deletion in the Extended Active Site of Human Carbonic Anhydrase II - K170P Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Boone, C.D, Rasi, V, McKenna, R. Deposit date: 2014-06-05 Release date: 2015-03-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.599 Å) Cite: Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II. Febs J., 282, 2015
4QK3	Structural and Catalytic Effects of Proline Substitution and Surface Loop Deletion in the Extended Active Site of Human Carbonic Anhydrase II - [delta]230-240 Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Boone, C.D, Rasi, V, McKenna, R. Deposit date: 2014-06-05 Release date: 2015-03-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.345 Å) Cite: Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II. Febs J., 282, 2015
3M5S	Carbonic Anhydrase II mutant H64C in complex with carbonate Descriptor: CARBONATE ION, Carbonic anhydrase 2, ZINC ION Authors: Schulze Wischeler, J, Heine, A, Klebe, G. Deposit date: 2010-03-13 Release date: 2011-05-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Mutational study on Carbonic Anhydrase II TO BE PUBLISHED
4RIV	A Carbonic Anhydrase IX Mimic in Complex with Saccharin Descriptor: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, Carbonic anhydrase 2, GLYCEROL, ... Authors: Mahon, B.P, McKenna, R. Deposit date: 2014-10-07 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.631 Å) Cite: Saccharin: A lead compound for structure-based drug design of carbonic anhydrase IX inhibitors. Bioorg.Med.Chem., 23, 2015
1HUH	DIFFERENCES IN ANIONIC INHIBITION OF HUMAN CARBONIC ANHYDRASE I REVEALED FROM THE STRUCTURES OF IODIDE AND GOLD CYANIDE INHIBITOR COMPLEXES Descriptor: CARBONIC ANHYDRASE I, IODIDE ION, ZINC ION Authors: Kumar, V, Kannan, K.K. Deposit date: 1993-10-28 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Differences in anionic inhibition of human carbonic anhydrase I revealed from the structures of iodide and gold cyanide inhibitor complexes. Acta Crystallogr.,Sect.D, 50, 1994

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