3T85

Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates

Summary for 3T85

Entry DOI	10.2210/pdb3t85/pdb
Related	3T82 3T83 3T84
Descriptor	Carbonic anhydrase 2, ZINC ION, 3,4-di-O-acetyl-6-O-sulfamoyl-alpha-D-mannopyranose, ... (4 entities in total)
Functional Keywords	alpha carbonic anhydrase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	29697.78
Authors	Hofmann, A.,Wang, C.K. (deposition date: 2011-08-01, release date: 2011-10-19, Last modification date: 2024-03-20)
Primary citation	Lopez, M.,Vu, H.,Wang, C.K.,Wolf, M.G.,Groenhof, G.,Innocenti, A.,Supuran, C.T.,Poulsen, S.A. Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133:18452-18462, 2011 Cited by PubMed: 21958118 DOI: 10.1021/ja207855c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation