3P58
Human Carbonic Anhydrase in complex with Benzyl (Methyl) Carbamodithoic Acid
Summary for 3P58
| Entry DOI | 10.2210/pdb3p58/pdb |
| Related | 3P5A 3P5L |
| Descriptor | Carbonic anhydrase 2, ZINC ION, benzyl(methyl)carbamodithioic acid, ... (4 entities in total) |
| Functional Keywords | carbothioates, hcaii inhibitors, lyase-inhibitor complex, lyase/inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29551.79 |
| Authors | Aggarwal, M.,McKenna, R. (deposition date: 2010-10-08, release date: 2011-10-19, Last modification date: 2024-02-21) |
| Primary citation | Carta, F.,Aggarwal, M.,Maresca, A.,Scozzafava, A.,McKenna, R.,Supuran, C.T. Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Chem.Commun.(Camb.), 48:1868-1870, 2012 Cited by PubMed: 22218610DOI: 10.1039/c2cc16395k PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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