PDB: 8880 resultsInfo pagesStatus searchChemie searchBIRD

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8Q3K	The open state of the ASFV apo-RNA polymerase Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ... Authors: Pilotto, S, Sykora, M, Cackett, G, Werner, F. Deposit date: 2023-08-04 Release date: 2024-02-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.92 Å) Cite: Structure of the recombinant RNA polymerase from African Swine Fever Virus. Nat Commun, 15, 2024
7DTH	Solution structure of RPB6, common subunit of RNA polymerases I, II, and III Descriptor: DNA-directed RNA polymerases I, II, and III subunit RPABC2 Authors: Okuda, M, Nishimura, Y. Deposit date: 2021-01-05 Release date: 2022-01-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Three human RNA polymerases interact with TFIIH via a common RPB6 subunit. Nucleic Acids Res., 50, 2022
8Q3B	The closed state of the ASFV apo-RNA polymerase Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ... Authors: Pilotto, S, Sykora, M, Cackett, G, Werner, F. Deposit date: 2023-08-03 Release date: 2024-02-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Structure of the recombinant RNA polymerase from African Swine Fever Virus. Nat Commun, 15, 2024
7DTI	Solution structure of the complex between RNA polymerase subunit RPB6 and TFIIH p62 PH domain Descriptor: DNA-directed RNA polymerases I, II, and III subunit RPABC2, ... Authors: Okuda, M, Nishimura, Y. Deposit date: 2021-01-05 Release date: 2022-08-10 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Three human RNA polymerases interact with TFIIH via a common RPB6 subunit. Nucleic Acids Res., 50, 2022
8ORQ	Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase open clamp conformation Descriptor: DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... Authors: Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. Deposit date: 2023-04-17 Release date: 2024-04-24 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
8RBO	Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation Descriptor: DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... Authors: Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. Deposit date: 2023-12-04 Release date: 2024-04-24 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
8C8H	Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme Descriptor: Core protein E11, DNA-directed RNA polymerase 133 kDa polypeptide, DNA-directed RNA polymerase 147 kDa polypeptide, ... Authors: Grimm, G, Bartuli, J, Fischer, U. Deposit date: 2023-01-20 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme To Be Published
7UM0	Structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with two DNA oligonucleotides containing the AR9 P077 promoter as determined by cryo-EM Descriptor: DNA (5'-D(P*GP*UP*U)-3'), DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, ... Authors: Leiman, P.G, Fraser, A, Sokolova, M.L. Deposit date: 2022-04-05 Release date: 2022-07-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
7UM1	Structure of bacteriophage AR9 non-virion RNAP polymerase holoenzyme determined by cryo-EM Descriptor: DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... Authors: Leiman, P.G, Fraser, A, Sokolova, M.L. Deposit date: 2022-04-05 Release date: 2022-07-06 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
7S00	X-ray structure of the phage AR9 non-virion RNA polymerase core Descriptor: DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... Authors: Leiman, P.G, Sokolova, M.L, Fraser, A. Deposit date: 2021-08-28 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
7S01	X-ray structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with a forked oligonucleotide containing the P077 promoter Descriptor: DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... Authors: Leiman, P.G, Sokolova, M.L, Gordeeva, J, Fraser, A, Severinov, K.V. Deposit date: 2021-08-28 Release date: 2022-07-06 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
4H3H	Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA poymerase II CTD peptide phosphorylated at SER-7 Descriptor: PHOSPHATE ION, Pol II CTD peptide, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ... Authors: Xiang, K, Tong, L. Deposit date: 2012-09-13 Release date: 2012-10-31 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72. Genes Dev., 26, 2012
1ARO	T7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYME Descriptor: MERCURY (II) ION, T7 LYSOZYME, T7 RNA POLYMERASE Authors: Steitz, T, Jeruzalmi, D. Deposit date: 1997-08-08 Release date: 1998-10-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme. EMBO J., 17, 1998
4RY5	C-terminal mutant (W550N) of HCV/J4 RNA polymerase Descriptor: HCV J4 RNA polymerase (NS5B), MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE Authors: Jaeger, J, Cherry, A, Dennis, C. Deposit date: 2014-12-13 Release date: 2014-12-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation. J.Virol., 89, 2015
3N6L	The crystal structure of RNA-dependent RNA polymerase of EV71 virus Descriptor: NICKEL (II) ION, RNA-dependent RNA polymerase Authors: Wu, Y, Rao, Z.H. Deposit date: 2010-05-26 Release date: 2011-06-15 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China. Protein Cell, 1, 2010
6IZX	The RNA-dependent RNA polymerase domain of dengue 2 NS5, bound with RK-0404678 Descriptor: 2-oxo-2H-1,3-benzoxathiol-5-yl acetate, COBALT (II) ION, Genome polyprotein, ... Authors: Shimizu, H, Sekine, S. Deposit date: 2018-12-20 Release date: 2019-12-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase. Plos Negl Trop Dis, 13, 2019
3HKZ	The X-ray crystal structure of RNA polymerase from Archaea Descriptor: DNA-directed RNA polymerase subunit 13, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... Authors: Murakami, K.S. Deposit date: 2009-05-26 Release date: 2009-06-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.4 Å) Cite: The X-ray crystal structure of RNA polymerase from Archaea. Nature, 451, 2008
6IZY	The RNA-dependent RNA polymerase domain of dengue 2 NS5 Descriptor: COBALT (II) ION, Genome polyprotein, ZINC ION Authors: Shimizu, H, Sekine, S. Deposit date: 2018-12-20 Release date: 2019-12-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase. Plos Negl Trop Dis, 13, 2019
4FLB	CID of human RPRD2 Descriptor: PRASEODYMIUM ION, Regulation of nuclear pre-mRNA domain-containing protein 2, SULFATE ION, ... Authors: Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) Deposit date: 2012-06-14 Release date: 2012-08-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.802 Å) Cite: RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
5MDU	Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe. Descriptor: CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ... Authors: Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J. Deposit date: 2016-11-13 Release date: 2017-04-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.02 Å) Cite: The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun, 8, 2017
2JLF	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2008-09-08 Release date: 2008-11-04 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
2JLG	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA-DEPENDENT RNA POLYMERASE Descriptor: 5'-D(*DT DT DT DC DCP)-3', GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2008-09-09 Release date: 2008-11-04 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
4PZ8	PCE1 guanylyltransferase bound to SPT5 CTD Descriptor: SULFATE ION, Transcription elongation factor spt5, mRNA-capping enzyme subunit alpha Authors: Doamekpor, S.K, Lima, C.D. Deposit date: 2014-03-28 Release date: 2014-06-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
4PZ7	PCE1 guanylyltransferase Descriptor: GLYCEROL, SULFATE ION, mRNA-capping enzyme subunit alpha Authors: Doamekpor, S.K, Lima, C.D. Deposit date: 2014-03-28 Release date: 2014-06-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.109 Å) Cite: How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
3NFG	Crystal structure of Dimerization module of RNA polymerase I subcomplex A49/A34.5 Descriptor: DNA-directed RNA polymerase I subunit RPA34, DNA-directed RNA polymerase I subunit RPA49 Authors: Geiger, S.R. Deposit date: 2010-06-10 Release date: 2010-09-08 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.51 Å) Cite: RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex. Mol.Cell, 39, 2010

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