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6WGZ
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BU of 6wgz by Molmil
Crystal structure of HyBcl-2-4 with HyBak1 BH3
Descriptor: ACETATE ION, Bak, Bcl-2-like 4, ...
Authors:Kvansakul, M, Hinds, M.G, Banjara, S.
Deposit date:2020-04-07
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of HyBcl-2-4 with HyBak1 BH3 and HyBax BH3
To Be Published
4RWF
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BU of 4rwf by Molmil
Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin
Descriptor: 1,2-ETHANEDIOL, Adrenomedullin, Maltose transporter subunit, ...
Authors:Booe, J, Pioszak, A.
Deposit date:2014-12-03
Release date:2015-05-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
4TSM
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BU of 4tsm by Molmil
MBP-fusion protein of PilA1 from C. difficile R20291 residues 26-166
Descriptor: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein, pilin chimera, ...
Authors:Piepenbrink, K.H, Sundberg, E.J.
Deposit date:2014-06-19
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile.
Structure, 23, 2015
6XDS
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BU of 6xds by Molmil
Crystal structure of MBP-TREM2 Ig domain fusion with fragment, 2-((4-bromophenyl)amino)ethan-1-ol
Descriptor: 2-[(4-bromophenyl)amino]ethan-1-ol, DIMETHYL SULFOXIDE, Sugar ABC transporter substrate-binding protein,Triggering receptor expressed on myeloid cells 2, ...
Authors:Su, H.P.
Deposit date:2020-06-11
Release date:2021-02-17
Method:X-RAY DIFFRACTION (1.466 Å)
Cite:Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.
Protein Expr.Purif., 179, 2021
6XRX
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BU of 6xrx by Molmil
Crystal structure of the mosquito protein AZ1 as an MBP fusion
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein, ...
Authors:Pedersen, L.C, Mueller, G.A, Foo, A.C.Y.
Deposit date:2020-07-14
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism.
Proc.Natl.Acad.Sci.USA, 118, 2021
4RWG
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BU of 4rwg by Molmil
Crystal structure of the CLR:RAMP1 extracellular domain heterodimer with bound high affinity CGRP analog
Descriptor: CGRP analog, MAGNESIUM ION, Maltose-binding periplasmic protein, ...
Authors:Booe, J, Pioszak, A.
Deposit date:2014-12-03
Release date:2015-05-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
6XDJ
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BU of 6xdj by Molmil
Crystal Structure Analysis of MBP-SIN3
Descriptor: Maltodextrin-binding protein,Transcriptional regulatory protein SIN3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Seo, H.-S, Dhe-Paganon, S.
Deposit date:2020-06-10
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure Analysis of MBP-SIN3
To be published
6XSW
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BU of 6xsw by Molmil
Structure of the Notch3 NRR in complex with an antibody Fab Fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-N3 Fab Heavy Chain, ...
Authors:Bard, J.
Deposit date:2020-07-16
Release date:2021-07-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells.
Cell Rep Med, 2, 2021
6X91
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BU of 6x91 by Molmil
Crystal structure of MBP-fused human APOBEC1
Descriptor: CACODYLATE ION, Maltodextrin-binding protein, C->U-editing enzyme APOBEC-1 chimera, ...
Authors:Wolfe, A.D, Li, S.-X, Chen, X.S.
Deposit date:2020-06-02
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity.
NAR Cancer, 2, 2020
6YBK
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BU of 6ybk by Molmil
Structure of MBP-Mcl-1 in complex with compound 4d
Descriptor: (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-(pyrazin-2-ylmethoxy)phenyl]propanoic acid, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, ...
Authors:Dokurno, P, Surgenor, A.E, Murray, J.B.
Deposit date:2020-03-17
Release date:2020-11-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor.
J.Med.Chem., 63, 2020
5B6H
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BU of 5b6h by Molmil
Crystal structure of an APRT from Yersinia pseudotuberculosis in complex with AMP.
Descriptor: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, CHLORIDE ION, ...
Authors:Pavithra, G.C, Ramagopal, U.A.
Deposit date:2016-05-27
Release date:2017-05-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an APRT from Yersinia pseudotuberculosis in complex with AMP.
To be published
5BK2
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BU of 5bk2 by Molmil
Crystal structure of maltose binding protein in complex with a peristeric synthetic antibody
Descriptor: CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
Authors:Mukherjee, S, Kossiakoff, A.A.
Deposit date:2017-09-12
Release date:2018-01-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5BK1
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BU of 5bk1 by Molmil
Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody
Descriptor: CHLORIDE ION, GLYCEROL, Maltose binding protein, ...
Authors:Mukherjee, S, Kossiakoff, A.A.
Deposit date:2017-09-12
Release date:2018-01-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5B3X
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BU of 5b3x by Molmil
Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in P41212 form
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Hanazono, Y, Takeda, K, Miki, K.
Deposit date:2016-03-17
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
Sci Rep, 6, 2016
5AMR
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BU of 5amr by Molmil
Structure of the La Crosse Bunyavirus polymerase in complex with the 3' viral RNA
Descriptor: RNA, RNA POLYMERASE L
Authors:Reguera, J, Gerlach, P, Cusack, S.
Deposit date:2015-03-12
Release date:2015-06-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell(Cambridge,Mass.), 161, 2015
5B3Z
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BU of 5b3z by Molmil
Crystal structure of hPin1 WW domain (5-39) fused with maltose-binding protein
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Hanazono, Y, Takeda, K, Miki, K.
Deposit date:2016-03-17
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
Sci Rep, 6, 2016
5BV0
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BU of 5bv0 by Molmil
Crystal Structure of a Complex Between the SNARE Nyv1 and the HOPS Vps33-Vps16 subcomplex from Chaetomium thermophilum
Descriptor: SM (Sec1/Munc18-like) protein, SNARE domain, Vps16
Authors:Baker, R.W, Jeffrey, P.D, Hughson, F.M.
Deposit date:2015-06-04
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015
5AZ6
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BU of 5az6 by Molmil
Crystal structure of MBP-Tom20 fusion protein with a 2-residue spacer in the connector helix
Descriptor: Maltose-binding periplasmic protein,Mitochondrial import receptor subunit TOM20 homolog, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Matsuoka, R, Kohda, D.
Deposit date:2015-09-27
Release date:2016-01-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Rational design of crystal contact-free space in protein crystals for analyzing spatial distribution of motions within protein molecules.
Protein Sci., 25, 2016
5BJZ
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BU of 5bjz by Molmil
Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ...
Authors:Mukherjee, S, Kossiakoff, A.A.
Deposit date:2017-09-12
Release date:2018-01-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5BMY
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BU of 5bmy by Molmil
Crystal structure of hPin1 WW domain (5-21) fused with maltose-binding protein
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Hanazono, Y, Takeda, K, Miki, K.
Deposit date:2015-05-25
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
Sci Rep, 6, 2016
1SVX
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BU of 1svx by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein
Descriptor: Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein
Authors:Binz, H.K, Amstutz, P, Kohl, A, Stumpp, M.T, Briand, C, Forrer, P, Gruetter, M.G, Plueckthun, A.
Deposit date:2004-03-30
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
1T95
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BU of 1t95 by Molmil
Crystal Structure of the Shwachman-Bodian-Diamond Syndrome Protein Orthologue from Archaeoglobus fulgidus
Descriptor: Hypothetical protein AF0491
Authors:Shammas, C, Warren, A.J.
Deposit date:2004-05-14
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome.
J.Biol.Chem., 280, 2005
1S7E
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BU of 1s7e by Molmil
Solution structure of HNF-6
Descriptor: Hepatocyte nuclear factor 6
Authors:Liao, X, Sheng, W.
Deposit date:2004-01-29
Release date:2004-12-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the hepatocyte nuclear factor 6alpha and its interaction with DNA.
J.Biol.Chem., 279, 2004
1SAV
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BU of 1sav by Molmil
HUMAN ANNEXIN V WITH PROLINE SUBSTITUTION BY THIOPROLINE
Descriptor: ANNEXIN V, CALCIUM ION
Authors:Medrano, F.J, Minks, C, Budisa, N, Huber, R.
Deposit date:1997-11-24
Release date:1998-05-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins.
J.Mol.Biol., 223, 1992
1R6Z
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BU of 1r6z by Molmil
The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)
Descriptor: Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L.
Deposit date:2003-10-17
Release date:2004-01-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003

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