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2HHE
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OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA CHAINS IN HUMAN AND BOVINE HEMOGLOBIN
Descriptor: HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
Authors:Gilliland, G.L, Pechik, I, Fronticelli, C, Ji, X.
Deposit date:1994-09-29
Release date:1995-01-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chloride ion independence of the Bohr effect in a mutant human hemoglobin beta (V1M+H2deleted).
J.Biol.Chem., 269, 1994
2HHF
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X-ray crystal structure of oxidized human mitochondrial branched chain aminotransferase (hBCATm)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Branched-chain-amino-acid aminotransferase, mitochondrial, ...
Authors:Yennawar, N.H, Hutson, S.M.
Deposit date:2006-06-28
Release date:2006-10-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human Mitochondrial Branched Chain Aminotransferase Isozyme: STRUCTURAL ROLE OF THE CXXC CENTER IN CATALYSIS.
J.Biol.Chem., 281, 2006
2HHG
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Structure of Protein of Unknown Function RPA3614, Possible Tyrosine Phosphatase, from Rhodopseudomonas palustris CGA009
Descriptor: Hypothetical protein RPA3614, PHOSPHATE ION, SODIUM ION
Authors:Binkowski, T.A, Evdokimova, E, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-06-28
Release date:2006-07-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Hypothetical protein RPA3614 from Rhodopseudomonas palustris CGA009
To be published
2HHH
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Crystal structure of kasugamycin bound to the 30S ribosomal subunit
Descriptor: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Schluenzen, F.
Deposit date:2006-06-28
Release date:2006-09-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Nat.Struct.Mol.Biol., 13, 2006
2HHI
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The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a novel class of beta-grasp proteins
Descriptor: Immunogenic protein MPT64
Authors:Wang, Z, Potter, B.M, Gray, A.M, Sacksteder, K.A, Geisbrecht, B.V, Laity, J.H.
Deposit date:2006-06-28
Release date:2006-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Solution Structure of Antigen MPT64 from Mycobacterium tuberculosis Defines a New Family of Beta-Grasp Proteins.
J.Mol.Biol., 366, 2007
2HHJ
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Human bisphosphoglycerate mutase complexed with 2,3-bisphosphoglycerate (15 days)
Descriptor: (2R)-2,3-diphosphoglyceric acid, 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, ...
Authors:Wang, Y, Gong, W.
Deposit date:2006-06-28
Release date:2006-10-24
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase.
J.Biol.Chem., 281, 2006
2HHK
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Reaction centre from Rhodobacter sphaeroides strain R-26.1 complexed with dibrominated phosphatidylglycerol
Descriptor: (1R)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (9S,10S)-9,10-DIBROMOOCTADECANOATE, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, BACTERIOCHLOROPHYLL A, ...
Authors:Roszak, A.W, Gardiner, A.T, Isaacs, N.W, Cogdell, R.J.
Deposit date:2006-06-28
Release date:2007-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Brominated Lipids Identify Lipid Binding Sites on the Surface of the Reaction Center from Rhodobacter sphaeroides.
Biochemistry, 46, 2007
2HHL
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Crystal structure of the human small CTD phosphatase 3 isoform 1
Descriptor: 12-TUNGSTOPHOSPHATE, CTD small phosphatase-like protein
Authors:Malashkevich, V.N, Toro, R, Ramagopal, U, Sauder, J.M, Schwinn, K.D, Thompson, D.A, Rutter, M.E, Dickey, M, Groshong, C, Bain, K.T, Adams, J.M, Reyes, C, Rooney, I, Powell, A, Boice, A, Gheyi, T, Ozyurt, S, Atwell, S, Wasserman, S.R, Emtage, S, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-06-28
Release date:2006-08-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
2HHM
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STRUCTURE OF INOSITOL MONOPHOSPHATASE, THE PUTATIVE TARGET OF LITHIUM THERAPY
Descriptor: GADOLINIUM ATOM, INOSITOL MONOPHOSPHATASE, SULFATE ION
Authors:Bone, R.
Deposit date:1992-10-20
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of inositol monophosphatase, the putative target of lithium therapy.
Proc.Natl.Acad.Sci.USA, 89, 1992
2HHN
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BU of 2hhn by Molmil
Cathepsin S in complex with non covalent arylaminoethyl amide.
Descriptor: Cathepsin S, N-[(1R)-1-[(BENZYLSULFONYL)METHYL]-2-{[(1S)-1-METHYL-2-{[4-(TRIFLUOROMETHOXY)PHENYL]AMINO}ETHYL]AMINO}-2-OXOETHYL]MORPHOLINE-4-CARBOXAMIDE, SULFATE ION
Authors:Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S, Kulathila, R, Clark, K.
Deposit date:2006-06-28
Release date:2007-05-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers
Bioorg.Med.Chem.Lett., 16, 2006
2HHO
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BU of 2hho by Molmil
NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures
Descriptor: Insulin A chain, Insulin B chain
Authors:Hua, Q.X, Nakagawa, S, Hu, S.Q, Jia, W, Weiss, M.A.
Deposit date:2006-06-28
Release date:2006-07-18
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain.
J.Biol.Chem., 281, 2006
2HHP
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BU of 2hhp by Molmil
Structure of yeast poly(A) polymerase in a closed conformation.
Descriptor: CITRATE ANION, MAGNESIUM ION, Poly(A) polymerase
Authors:Bohm, A, Toth, J.
Deposit date:2006-06-28
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
2HHQ
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BU of 2hhq by Molmil
O6-methyl-guanine:T pair in the polymerase-10 basepair position
Descriptor: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*AP*TP*GP*A)-3', DNA polymerase I, ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHS
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BU of 2hhs by Molmil
O6-methyl:C pair in the polymerase-10 basepair position
Descriptor: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*GP*CP*AP*TP*GP*A)-3', DNA polymerase I, ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHT
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C:O6-methyl-guanine pair in the polymerase-2 basepair position
Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*CP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA polymerase I, ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHU
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BU of 2hhu by Molmil
C:O6-methyl-guanine in the polymerase postinsertion site (-1 basepair position)
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*CP*C)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*GP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHV
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T:O6-methyl-guanine in the polymerase-2 basepair position
Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*TP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHW
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ddTTP:O6-methyl-guanine pair in the polymerase active site, in the closed conformation
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHX
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O6-methyl-guanine in the polymerase template preinsertion site
Descriptor: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*G)-3', DNA Polymerase I, ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHZ
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BU of 2hhz by Molmil
Crystal structure of a pyridoxamine 5'-phosphate oxidase-related protein (ssuidraft_2804) from streptococcus suis 89/1591 at 2.00 A resolution
Descriptor: ACETATE ION, CHLORIDE ION, PHOSPHATE ION, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-06-28
Release date:2006-08-15
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Pyridoxamine 5'-phosphate oxidase-related (ZP_00875725.1) from STREPTOCOCCUS SUIS 89-1591 at 2.00 A resolution
To be published
2HI0
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BU of 2hi0 by Molmil
Crystal structure of putative phosphoglycolate phosphatase (YP_619066.1) from Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 at 1.51 A resolution
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-06-28
Release date:2006-08-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Crystal structure of putative phosphoglycolate phosphatase (YP_619066.1) from Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 at 1.51 A resolution
To be Published
2HI1
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BU of 2hi1 by Molmil
The structure of a putative 4-hydroxythreonine-4-phosphate dehydrogenase from Salmonella typhimurium.
Descriptor: 4-hydroxythreonine-4-phosphate dehydrogenase 2
Authors:Cuff, M.E, Quartey, P, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-06-28
Release date:2006-07-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of a putative 4-hydroxythreonine-4-phosphate dehydrogenase from Salmonella typhimurium.
To be Published
2HI2
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BU of 2hi2 by Molmil
Crystal structure of native Neisseria gonorrhoeae Type IV pilin at 2.3 Angstroms Resolution
Descriptor: Fimbrial protein, HEPTANE-1,2,3-TRIOL, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ...
Authors:Craig, L, Arvai, A.S, Tainer, J.A.
Deposit date:2006-06-28
Release date:2006-09-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions.
Mol.Cell, 23, 2006
2HI3
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BU of 2hi3 by Molmil
Solution structure of the homeodomain-only protein HOP
Descriptor: Homeodomain-only protein
Authors:Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W.
Deposit date:2006-06-28
Release date:2007-01-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Analysis of the structure and function of the transcriptional coregulator HOP
Biochemistry, 45, 2006
2HI4
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BU of 2hi4 by Molmil
Crystal Structure of Human Microsomal P450 1A2 in complex with alpha-naphthoflavone
Descriptor: 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, Cytochrome P450 1A2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sansen, S, Yano, J.K, Reynald, R.L, Schoch, G.S, Stout, C.D, Johnson, E.F.
Deposit date:2006-06-29
Release date:2007-02-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.
J.Biol.Chem., 282, 2007

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