2HHK
Reaction centre from Rhodobacter sphaeroides strain R-26.1 complexed with dibrominated phosphatidylglycerol
Summary for 2HHK
| Entry DOI | 10.2210/pdb2hhk/pdb |
| Related | 2HG3 2HG9 2HH1 2HIT 2HJ6 |
| Descriptor | Reaction center protein L chain, PHOSPHATE ION, CARDIOLIPIN, ... (16 entities in total) |
| Functional Keywords | photosynthesis, photosynthetic reaction center, lipid binding sites, brominated lipid, membrane protein, photosynthesis-membrane protein complex, photosynthesis/membrane protein |
| Biological source | Rhodobacter sphaeroides More |
| Cellular location | Cellular chromatophore membrane; Multi-pass membrane protein: P0C0Y8 P0C0Y9 Cellular chromatophore membrane; Single-pass membrane protein: P0C0Y7 |
| Total number of polymer chains | 3 |
| Total formula weight | 106341.33 |
| Authors | Roszak, A.W.,Gardiner, A.T.,Isaacs, N.W.,Cogdell, R.J. (deposition date: 2006-06-28, release date: 2007-03-27, Last modification date: 2024-04-03) |
| Primary citation | Roszak, A.W.,Gardiner, A.T.,Isaacs, N.W.,Cogdell, R.J. Brominated Lipids Identify Lipid Binding Sites on the Surface of the Reaction Center from Rhodobacter sphaeroides. Biochemistry, 46:2909-2916, 2007 Cited by PubMed Abstract: This study describes the use of brominated phospholipids to distinguish between lipid and detergent binding sites on the surface of a typical alpha-helical membrane protein. Reaction centers isolated from Rhodobacter sphaeroides were cocrystallized with added brominated phospholipids. X-ray structural analysis of these crystals has revealed the presence of two lipid binding sites from the characteristic strong X-ray scattering from the bromine atoms. These results demonstrate the usefulness of this approach to mapping lipid binding sites at the surface of membrane proteins. PubMed: 17315985DOI: 10.1021/bi062154i PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
