PDB: 1140 resultsInfo pagesStatus searchChemie searchBIRD

---

8IVW	Crystal structure of NRP2 in complex with aNRP2-10 Fab fragment Descriptor: Heavy chian of antibody 10V8 Fab fragment, Light chain of antibody 10V8 Fab fragment, Neuropilin-2 Authors: Geng, Y, Zhai, L. Deposit date: 2023-03-29 Release date: 2023-07-12 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.205 Å) Cite: Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
4RN5	B1 domain of human Neuropilin-1 with acetate ion in a ligand-binding site Descriptor: ACETATE ION, GLYCEROL, Neuropilin-1, ... Authors: Allerston, C.K, Yelland, T.S, Jarvis, A, Jenkins, K, Winfield, N, Cheng, L, Jia, H, Zachary, I, Selwood, D.L, Djordjevic, S. Deposit date: 2014-10-23 Release date: 2015-10-28 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Conserved water molecules in a ligand-binding site of neuropilin-1 To be Published
5DQ0	Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. Deposit date: 2015-09-14 Release date: 2016-09-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site To Be Published
5HZ7	High-resolution crystal structure of the minor DNA-binding pilin ComP from Neisseria meningitidis in fusion with MBP Descriptor: 1,2-ETHANEDIOL, ComP, SODIUM ION, ... Authors: Berry, J.-L. Deposit date: 2016-02-02 Release date: 2016-05-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.43 Å) Cite: A Comparative Structure/Function Analysis of Two Type IV Pilin DNA Receptors Defines a Novel Mode of DNA Binding. Structure, 24, 2016
4QDQ	Physical basis for Nrp2 ligand binding Descriptor: GLYCEROL, Neuropilin-2, SULFATE ION Authors: Parker, M.W, Vander Kooi, C.W. Deposit date: 2014-05-14 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
5MQG	Crystal structure of CREBBP bromodomain complexed with CBP015 Descriptor: 1-(4-azanyl-3-methoxy-phenyl)ethanone, CREB-binding protein Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-20 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
5MGK	Crystal Structure of BAZ2A bromodomain in complex with 4-propionyl-pyrrole derivative 2 Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, methyl 4-propanoyl-1~{H}-pyrrole-2-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.301 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MPZ	Crystal structure of CREBBP bromodomain complexed with CBP007 Descriptor: CREB-binding protein, methyl 2-oxidanylidene-3~{H}-1,3-benzoxazole-6-carboxylate Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-19 Release date: 2017-05-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
4QDS	Physical basis for Nrp2 ligand binding Descriptor: ACETATE ION, GLYCEROL, Neuropilin-2 Authors: Parker, M.W, Vander Kooi, C.W. Deposit date: 2014-05-14 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
5MGG	Crystal Structure of BAZ2B bromodomain in complex with 4-chloropyridine derivative 3 Descriptor: 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2B Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGJ	Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridine derivative 1 Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGL	Crystal Structure of BAZ2A bromodomain in complex with 4-chloropyridine derivative 3 Descriptor: 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.651 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGM	Crystal Structure of BAZ2A bromodomain in complex with acetophenone derivative 4 Descriptor: 1-(3-pyrimidin-2-yloxyphenyl)ethanone, Bromodomain adjacent to zinc finger domain protein 2A Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MQE	Crystal structure of CREBBP bromodomain complexed with CBP006 Descriptor: 4-bromanyl-~{N}-methyl-1~{H}-pyrrole-2-carboxamide, CREB-binding protein Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-20 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
5MQK	Crystal structure of CREBBP bromodomain complexed with CBP019 Descriptor: 1-(1-methylindol-3-yl)ethanone, CREB-binding protein Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-20 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
5MGF	Crystal Structure of BAZ2B bromodomain in complex with 4-propionyl-pyrrole derivative 2 Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, methyl 4-propanoyl-1~{H}-pyrrole-2-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGE	Crystal structure of BAZ2B bromodomain in complex with 1-methylpyridine derivative 1 Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
4GZ8	Mouse Semaphorin 3A, domains Sema-PSI-IG Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... Authors: Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y. Deposit date: 2012-09-06 Release date: 2012-10-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat.Struct.Mol.Biol., 19, 2012
6IXZ	X-ray structure of sortase C from Clostridium perfringens SM101 Descriptor: Sortase family protein Authors: Kamitori, S, Tamai, E. Deposit date: 2018-12-12 Release date: 2019-08-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structures of major pilins in Clostridium perfringens demonstrate dynamic conformational change. Acta Crystallogr D Struct Biol, 75, 2019
4RDB	Crystal structure of an immunoreactive 32 kDa antigen PG49 (PG_0181) from Porphyromonas gingivalis W83 at 1.45 A resolution (PSI Community Target, Nakayama) Descriptor: 1,2-ETHANEDIOL, ACETONE, Immunoreactive 32 kDa antigen PG49 Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2014-09-18 Release date: 2014-12-03 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
3LIU	Crystal structure of Putative cell adhesion protein (YP_001304840.1) from Parabacteroides distasonis ATCC 8503 at 2.05 A resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2010-01-25 Release date: 2010-02-09 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.05 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
4K4K	Crystal structure of a putative cell adhesion protein (BACUNI_00621) from Bacteroides uniformis ATCC 8492 at 1.67 A resolution Descriptor: CHLORIDE ION, Putative cell adhesion protein Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2013-04-12 Release date: 2013-05-01 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.67 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
4JRF	Crystal structure of a putative cell adhesion protein (BACOVA_01548) from Bacteroides ovatus ATCC 8483 at 1.98 A resolution (PSI Community Target, Nakayama) Descriptor: CALCIUM ION, CHLORIDE ION, SULFATE ION, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2013-03-21 Release date: 2013-04-03 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.98 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
4JG5	Crystal structure of a putative cell adhesion protein (BDI_3519) from Parabacteroides distasonis ATCC 8503 at 2.34 A resolution (PSI Community Target, Nakayama) Descriptor: Putative cell adhesion protein Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2013-02-28 Release date: 2013-03-20 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.34 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
4Q98	Crystal structure of a fimbrilin (fimA) from Porphyromonas gingivalis W83 at 1.30 A resolution (PSI Community Target, Nakayama) Descriptor: Major fimbrial subunit protein, SODIUM ION Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2014-04-29 Release date: 2014-06-04 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016

<891011121314151617181920212223>