4QDQ

Physical basis for Nrp2 ligand binding

Summary for 4QDQ

• Entry DOI: 10.2210/pdb4qdq/pdb
• Related: 4QDR 4QDS
• Descriptor: Neuropilin-2, GLYCEROL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: coagulation factor domain, discoidin domain, receptor, vegf-c, membrane, cell adhesion
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein. Isoform s9: Secreted : O60462
• Total number of polymer chains: 2
• Total formula weight: 74902.32

Authors

Parker, M.W.,Vander Kooi, C.W. (deposition date: 2014-05-14, release date: 2015-04-15, Last modification date: 2023-09-20)

• Primary citation: Parker, M.W.,Linkugel, A.D.,Goel, H.L.,Wu, T.,Mercurio, A.M.,Vander Kooi, C.W.; Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form.; Structure, 23:677-687, 2015; PubMed: 25752543; DOI: 10.1016/j.str.2015.01.018

Experimental method

X-RAY DIFFRACTION (1.95 Å)