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4QDQ

Physical basis for Nrp2 ligand binding

Functional Information from GO Data
ChainGOidnamespacecontents
A0001525biological_processangiogenesis
A0005021molecular_functionvascular endothelial growth factor receptor activity
A0007411biological_processaxon guidance
A0017154molecular_functionsemaphorin receptor activity
A0038084biological_processvascular endothelial growth factor signaling pathway
B0001525biological_processangiogenesis
B0005021molecular_functionvascular endothelial growth factor receptor activity
B0007411biological_processaxon guidance
B0017154molecular_functionsemaphorin receptor activity
B0038084biological_processvascular endothelial growth factor signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL A 701
ChainResidue
ALYS547
APHE549
AGLU550
AARG562
AHOH856
AHOH868
AHOH903

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL A 702
ChainResidue
AHIS415
AARG572
AHOH942
AASN354
AGLY355

site_idAC3
Number of Residues8
DetailsBINDING SITE FOR RESIDUE GOL A 703
ChainResidue
ATRP372
AMET373
AVAL374
AARG376
AHIS381
AHIS554
AHOH833
AHOH939

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 704
ChainResidue
AHIS312
AGLN345
AARG421
ALYS533

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL B 701
ChainResidue
BGLY355
BHIS415
BSER416

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 B 702
ChainResidue
BTRP372
BMET373
BVAL374
BARG376
BHIS554
BHOH829

Functional Information from PROSITE/UniProt
site_idPS01285
Number of Residues30
DetailsFA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. GWtpnldsnke......YLqVDlrfltmLtaIaTQG
ChainResidueDetails
AGLY317-GLY346
AGLY473-GLY505

site_idPS01286
Number of Residues17
DetailsFA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Pqtwhsgia..LRlELfGC
ChainResidueDetails
APRO411-CYS427
APRO575-CYS592

226707

PDB entries from 2024-10-30

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