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6Z4L
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BU of 6z4l by Molmil
A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 9 in P21 space group
Descriptor: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
Authors:Amporndanai, K, Hasnain, S.S.
Deposit date:2020-05-25
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z4G
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BU of 6z4g by Molmil
A4V mutant of human SOD1 bound with ebselen in P21 space group
Descriptor: ACETATE ION, CHLORIDE ION, N-phenyl-2-selanylbenzamide, ...
Authors:Amporndanai, K, Hasnain, S.S.
Deposit date:2020-05-25
Release date:2020-09-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
1W6Z
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BU of 1w6z by Molmil
High Energy Tetragonal Lysozyme X-ray Structure
Descriptor: CHLORIDE ION, HOLMIUM (III) ATOM, LYSOZYME C
Authors:Jakoncic, J, Aslantas, M, Honkimaki, V, Di Michiel, M, Stojanoff, V.
Deposit date:2004-08-25
Release date:2004-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Anomalous Diffraction at Ultra-High Energy for Protein Crystallography.
J.Appl.Crystallogr., 39, 2006
4LD7
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BU of 4ld7 by Molmil
Crystal structure of AnaPT from Neosartorya fischeri
Descriptor: Dimethylallyl tryptophan synthase, SODIUM ION, TRIHYDROGEN THIODIPHOSPHATE
Authors:Zocher, G, Stehle, T.
Deposit date:2013-06-24
Release date:2013-12-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Catalytic Mechanism of Stereospecific Formation of cis-Configured Prenylated Pyrroloindoline Diketopiperazines by Indole Prenyltransferases.
Chem.Biol., 20, 2013
6Z3V
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BU of 6z3v by Molmil
A4V mutant of human SOD1 bound with N-aryl benzoisoselenazolone derivative 13 in P21 space group
Descriptor: 5-fluoranyl-~{N}-(3-morpholin-4-ylcarbonylphenyl)-2-selanyl-benzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
Authors:Amporndanai, K, Hasnain, S.S.
Deposit date:2020-05-22
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z4I
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BU of 6z4i by Molmil
A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 3 in P21 space group
Descriptor: ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
Authors:Amporndanai, K, Hasnain, S.S.
Deposit date:2020-05-25
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z4O
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BU of 6z4o by Molmil
A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 1 in P21 space group
Descriptor: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
Authors:Amporndanai, K, Hasnain, S.S.
Deposit date:2020-05-25
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6VFD
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BU of 6vfd by Molmil
Tryptophan synthase mutant Q114A in complex with cesium ion at the metal coordination site and 2-aminophenol quinonoid at the enzyme beta site
Descriptor: (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-3-[(2-hydroxyphenyl)amino]propanoic acid, 1,2-ETHANEDIOL, CESIUM ION, ...
Authors:Hilario, E, Fan, L, Dunn, M.F, Mueller, L.J.
Deposit date:2020-01-03
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Tryptophan synthase mutant Q114A in complex with cesium ion at the metal coordination site and 2-aminophenol quinonoid at the enzyme beta site.
To be Published
6Z4K
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BU of 6z4k by Molmil
A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 6 in P21 space group
Descriptor: CHLORIDE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
Authors:Amporndanai, K, Hasnain, S.S.
Deposit date:2020-05-25
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
4J7Y
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BU of 4j7y by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: D-gamma-glutamyl-(Z)-N-(carboxymethylidene)-S-[(2R)-2-hydroxy-4-phenylbutyl]-L-cysteinamide, Leukotriene C4 synthase, NICKEL (II) ION, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-14
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
6Z4J
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BU of 6z4j by Molmil
A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 5 in P21 space group
Descriptor: CHLORIDE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
Authors:Amporndanai, K, Hasnain, S.S.
Deposit date:2020-05-25
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
1UUZ
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BU of 1uuz by Molmil
IVY:A NEW FAMILY OF PROTEIN
Descriptor: INHIBITOR OF VERTEBRATE LYSOZYME, LYSOZYME C
Authors:Abergel, C, Lembo, F, Byrne, D, Maza, C, Claverie, J.M.
Deposit date:2004-01-12
Release date:2004-01-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Evolution of the Ivy Protein Family, Unexpected Lysozyme Inhibitors in Gram-Negative Bacteria.
Proc.Natl.Acad.Sci.USA, 104, 2007
4JRZ
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BU of 4jrz by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-03-22
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4JC7
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BU of 4jc7 by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-21
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4JCZ
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BU of 4jcz by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-22
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4J7T
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BU of 4j7t by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: D-gamma-glutamyl-S-(4-phenylbutyl)-L-cysteinylglycine, Leukotriene C4 synthase, NICKEL (II) ION, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-14
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
3NUD
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BU of 3nud by Molmil
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis complexed with phenylalanine
Descriptor: PHENYLALANINE, PHOSPHATE ION, Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
Authors:Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M.
Deposit date:2010-07-06
Release date:2010-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
3NV8
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BU of 3nv8 by Molmil
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol pyruvate and manganese (thesit-free)
Descriptor: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:Parker, E.J, Jameson, G.B, Jiao, W, Hutton, R.H, Webby, C.J, Baker, E.N, Baker, H.M.
Deposit date:2010-07-08
Release date:2010-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
2G2P
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BU of 2g2p by Molmil
Crystal Structure of E.coli transthyretin-related protein with bound Zn and Br
Descriptor: BROMIDE ION, SULFATE ION, Transthyretin-like protein, ...
Authors:Lundberg, E, Backstrom, S, Sauer, U.H, Sauer-Eriksson, A.E.
Deposit date:2006-02-16
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The transthyretin-related protein: structural investigation of a novel protein family
J.Struct.Biol., 155, 2006
6DFU
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BU of 6dfu by Molmil
Tryptophan--tRNA ligase from Haemophilus influenzae.
Descriptor: TRYPTOPHAN, Tryptophan--tRNA ligase
Authors:Osipiuk, J, Maltseva, N, Mulligan, R, Grimshaw, S, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-05-15
Release date:2018-05-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Tryptophan--tRNA ligase from Haemophilus influenzae.
to be published
2G2N
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BU of 2g2n by Molmil
Crystal Structure of E.coli transthyretin-related protein with bound Zn
Descriptor: SULFATE ION, Transthyretin-like protein, ZINC ION
Authors:Lundberg, E, Backstrom, S, Sauer, U.H, Sauer-Eriksson, A.E.
Deposit date:2006-02-16
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The transthyretin-related protein: structural investigation of a novel protein family
J.Struct.Biol., 155, 2006
5U9M
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BU of 5u9m by Molmil
Copper-Zinc Superoxide Dismutase is Activated through a Sulfenic Acid Intermediate at a Copper-ion Entry Site
Descriptor: Superoxide dismutase 1 copper chaperone, Superoxide dismutase [Cu-Zn], ZINC ION
Authors:Taylor, A.B, Hart, P.J, Winkler, D.D.
Deposit date:2016-12-16
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Copper-zinc superoxide dismutase is activated through a sulfenic acid intermediate at a copper ion entry site.
J. Biol. Chem., 292, 2017
5VAI
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BU of 5vai by Molmil
Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein
Descriptor: Glucagon-like peptide 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhang, Y, Sun, B, Feng, D, Hu, H, Chu, M, Qu, Q, Tarrasch, J.T, Li, S, Kobilka, T.S, Kobilka, B.K, Skiniotis, G.
Deposit date:2017-03-27
Release date:2017-05-24
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.
Nature, 546, 2017
5UKL
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BU of 5ukl by Molmil
Human GRK2 in complex with Gbetagamma subunits and CCG222886 (14bd)
Descriptor: 2-{5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluorophenyl}-N-[2-(1H-pyrazol-4-yl)ethyl]acetamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Cato, M.C, Homan, K.T, Tesmer, J.J.G.
Deposit date:2017-01-23
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.
J. Med. Chem., 60, 2017
6CK2
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BU of 6ck2 by Molmil
Insulin analog containing a YB26W mutation
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Rege, N.K, Yee, V.C, Weiss, M.A.
Deposit date:2018-02-27
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-based stabilization of insulin as a therapeutic protein assembly via enhanced aromatic-aromatic interactions.
J. Biol. Chem., 293, 2018

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