6HMR
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![BU of 6hmr by Molmil](/molmil-images/mine/6hmr) | Crystal structure of human Casein Kinase I delta in complex with a photoswitchable 2-Azothiazole-based inhibitor (compound 2) | Descriptor: | 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-[(~{E})-phenyldiazenyl]-1,3-thiazol-5-yl]pyridin-2-yl]propanamide, Casein kinase I isoform delta, MALONIC ACID | Authors: | Pichlo, C, Schehr, M, Charl, J, Brunstein, E, Peifer, C, Baumann, U. | Deposit date: | 2018-09-12 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.782 Å) | Cite: | 2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach. Photochem. Photobiol. Sci., 18, 2019
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4S2U
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![BU of 4s2u by Molmil](/molmil-images/mine/4s2u) | Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli | Descriptor: | MAGNESIUM ION, Ribose-phosphate pyrophosphokinase | Authors: | Timofeev, V.I, Abramchik, Y.A, Muravieva, T.I, Iaroslavtceva, A.K, Stepanenko, V.N, Zhukhlistova, N.E, Esipov, R.S, Kuranova, I.P. | Deposit date: | 2015-01-23 | Release date: | 2016-01-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli To be Published
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1YVQ
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![BU of 1yvq by Molmil](/molmil-images/mine/1yvq) | The low salt (PEG) crystal structure of CO Hemoglobin E (betaE26K) approaching physiological pH (pH 7.5) | Descriptor: | CARBON MONOXIDE, Hemoglobin alpha chain, Hemoglobin beta chain, ... | Authors: | Malashkevich, V.N, Balazs, T.C, Almo, S.C, Hirsch, R.E. | Deposit date: | 2005-02-16 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of CO Hemoglobin E (betaE26K) approaching physiological pH (pH 7.5) To be Published
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2OS1
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![BU of 2os1 by Molmil](/molmil-images/mine/2os1) | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes | Descriptor: | ACTINONIN, NICKEL (II) ION, Peptide deformylase, ... | Authors: | Kim, E.E, Kim, K.-H, Moon, J.H, Choi, K, Lee, H.K, Park, H.S. | Deposit date: | 2007-02-05 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes To be Published
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3DNF
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![BU of 3dnf by Molmil](/molmil-images/mine/3dnf) | |
5VM8
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![BU of 5vm8 by Molmil](/molmil-images/mine/5vm8) | |
2HEM
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![BU of 2hem by Molmil](/molmil-images/mine/2hem) | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit. | Descriptor: | 5'-R(P*GP*GP*GP*AP*AP*GP*GP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*CP*GP*GP*CP*CP*C)-3' | Authors: | Zhao, Q, Nagaswamy, U, Lee, H, Xia, Y, Gao, X, Fox, G. | Deposit date: | 2006-06-21 | Release date: | 2006-09-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit Nucleic Acids Res., 33, 2005
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1JWE
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![BU of 1jwe by Molmil](/molmil-images/mine/1jwe) | NMR Structure of the N-Terminal Domain of E. Coli Dnab Helicase | Descriptor: | PROTEIN (DNAB HELICASE) | Authors: | Weigelt, J, Brown, S.E, Miles, C.S, Dixon, N.E, Otting, G. | Deposit date: | 1999-01-22 | Release date: | 1999-01-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer. Structure Fold.Des., 7, 1999
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1YVT
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![BU of 1yvt by Molmil](/molmil-images/mine/1yvt) | The high salt (phosphate) crystal structure of CO Hemoglobin E (Glu26Lys) at physiological pH (pH 7.35) | Descriptor: | CARBON MONOXIDE, GLYCEROL, Hemoglobin alpha chain, ... | Authors: | Malashkevich, V.N, Balazs, T.C, Almo, S.C, Hirsch, R.E. | Deposit date: | 2005-02-16 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The high salt (phosphate) crystal structure of CO Hemoglobin E (Glu26Lys) at physiological pH (pH 7.35) To be Published
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3QIB
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![BU of 3qib by Molmil](/molmil-images/mine/3qib) | Crystal structure of the 2B4 TCR in complex with MCC/I-Ek | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 beta chain, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. | Deposit date: | 2011-01-26 | Release date: | 2011-04-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k). J.Immunol., 186, 2011
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4HKH
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![BU of 4hkh by Molmil](/molmil-images/mine/4hkh) | Structure of the Hcp1 protein from E. coli EAEC 042 pathovar, mutants N93W-S158W | Descriptor: | Putative type VI secretion protein, SULFATE ION | Authors: | Douzi, B, Spinelli, S, Derrez, E, Blangy, S, Brunet, Y.R, Cascales, E, Cambillau, C. | Deposit date: | 2012-10-15 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structure of the Hcp1 protein from E. coli EAEC 042 pathovar, mutants N93W-S158W To be Published
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2OVP
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![BU of 2ovp by Molmil](/molmil-images/mine/2ovp) | Structure of the Skp1-Fbw7 complex | Descriptor: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A | Authors: | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | Deposit date: | 2007-02-14 | Release date: | 2007-04-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases Mol.Cell, 26, 2007
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2R69
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![BU of 2r69 by Molmil](/molmil-images/mine/2r69) | Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution | Descriptor: | Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E | Authors: | Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2007-09-05 | Release date: | 2007-12-25 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat.Struct.Mol.Biol., 15, 2008
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3NXT
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![BU of 3nxt by Molmil](/molmil-images/mine/3nxt) | Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E-and Z-isomers of a Series of 5-substituted 2,4-diaminofuro[2m,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase | Descriptor: | 5-[(E)-2-cyclopropyl-2-(2-methoxyphenyl)ethenyl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Cody, V. | Deposit date: | 2010-07-14 | Release date: | 2010-12-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 66, 2010
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5XMX
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![BU of 5xmx by Molmil](/molmil-images/mine/5xmx) | Co-crystal structure of Inhibitor compound in complex with human PPARdelta LBD | Descriptor: | (E)-6-[2-[[[4-(furan-2-yl)phenyl]carbonyl-methyl-amino]methyl]phenoxy]-4-methyl-hex-4-enoic acid, Peroxisome proliferator-activated receptor delta | Authors: | Lakshminarasimhan, A, Rani, S.T, Senaiar, R.S, Krishnamurthy, N. | Deposit date: | 2017-05-16 | Release date: | 2018-05-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Novel highly selective peroxisome proliferator-activated receptor delta (PPAR delta) modulators with pharmacokinetic properties suitable for once-daily oral dosing. Bioorg. Med. Chem. Lett., 27, 2017
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7JQW
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![BU of 7jqw by Molmil](/molmil-images/mine/7jqw) | |
2OS3
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![BU of 2os3 by Molmil](/molmil-images/mine/2os3) | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes | Descriptor: | ACTINONIN, COBALT (II) ION, Peptide deformylase | Authors: | Kim, E.E, Kim, K.-H, Moon, J.H, Choi, K, Lee, H.K, Parh, H.S. | Deposit date: | 2007-02-05 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes To be Published
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2OS0
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![BU of 2os0 by Molmil](/molmil-images/mine/2os0) | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes | Descriptor: | NICKEL (II) ION, Peptide deformylase, SULFATE ION | Authors: | Kim, E.E, Kim, K.-H, Moon, J.H, Choi, K, Lee, H.K, Park, H.S. | Deposit date: | 2007-02-05 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes To be Published
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2Y0F
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![BU of 2y0f by Molmil](/molmil-images/mine/2y0f) | STRUCTURE OF GCPE (IspG) FROM THERMUS THERMOPHILUS HB27 | Descriptor: | 4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE, IRON/SULFUR CLUSTER | Authors: | Rekittke, I, Nonaka, T, Wiesner, J, Demmer, U, Warkentin, E, Jomaa, H, Ermler, U. | Deposit date: | 2010-12-02 | Release date: | 2011-01-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the E-1-Hydroxy-2-Methyl-But-2-Enyl-4-Diphosphate Synthase (Gcpe) from Thermus Thermophilus. FEBS Lett., 585, 2011
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4OXP
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![BU of 4oxp by Molmil](/molmil-images/mine/4oxp) | |
1MJZ
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![BU of 1mjz by Molmil](/molmil-images/mine/1mjz) | STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D97N | Descriptor: | INORGANIC PYROPHOSPHATASE | Authors: | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | Deposit date: | 1997-02-08 | Release date: | 1997-12-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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3HFU
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![BU of 3hfu by Molmil](/molmil-images/mine/3hfu) | Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide | Descriptor: | 1,2-ETHANEDIOL, AZIDE ION, HTH-type transcriptional regulator cynR | Authors: | Singer, A.U, Evdokimova, E, Kagan, O, Dong, A, Edwards, A.M, Savchenko, A. | Deposit date: | 2009-05-12 | Release date: | 2009-06-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide TO BE PUBLISHED
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1TMH
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![BU of 1tmh by Molmil](/molmil-images/mine/1tmh) | |
1EFC
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![BU of 1efc by Molmil](/molmil-images/mine/1efc) | INTACT ELONGATION FACTOR FROM E.COLI | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (ELONGATION FACTOR) | Authors: | Song, H, Parsons, M.R, Rowsell, S, Leonard, G, Phillips, S.E.V. | Deposit date: | 1998-11-24 | Release date: | 1999-03-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution. J.Mol.Biol., 285, 1999
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4HJT
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![BU of 4hjt by Molmil](/molmil-images/mine/4hjt) | |