PDB: 5617 resultsInfo pagesStatus searchChemie searchBIRD

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9F7F	UP1 in complex with Z1491353358 Descriptor: (3S)-1-(phenylsulfonyl)pyrrolidin-3-amine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-05-03 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
6NR9	hTRiC-hPFD Class5 Descriptor: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... Authors: Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. Deposit date: 2019-01-23 Release date: 2019-06-19 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (8.5 Å) Cite: The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
9GEA	Structure of UP1 S4DS6D phosphomimetic mutant Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-08-07 Release date: 2024-08-21 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Structure of UP1 S4DS6D phosphomimetic mutant To Be Published
9F1B	Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9GPJ	Structure of UP1 S4DS6D phosphomimetic mutant in complex with human telomeric repeat DNA Descriptor: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-09-08 Release date: 2024-09-25 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Structure of UP1 S4DS6D phosphomimetic mutant in complex with human telomeric repeat DNA To Be Published
9GMO	eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16 Descriptor: 28S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5.8S rRNA, ... Authors: Bothe, A, Ban, N, Kostova, K. Deposit date: 2024-08-29 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (2.59 Å) Cite: ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates. Biorxiv, 2024
6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
4Y1L	Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation Descriptor: RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9 Authors: Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y. Deposit date: 2015-02-08 Release date: 2015-05-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: RWD Domain as an E2 (Ubc9)-Interaction Module. J.Biol.Chem., 290, 2015
3A4S	The crystal structure of the SLD2:Ubc9 complex Descriptor: NFATC2-interacting protein, SUMO-conjugating enzyme UBC9 Authors: Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. Deposit date: 2009-07-14 Release date: 2010-02-02 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45 Proteins, 78, 2009
1HA1	HNRNP A1 (RBD1,2) FROM HOMO SAPIENS Descriptor: HNRNP A1 Authors: Shamoo, Y, Krueger, U, Rice, L, Williams, K.R, Steitz, T.A. Deposit date: 1996-10-30 Release date: 1997-05-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 A resolution. Nat.Struct.Biol., 4, 1997
4YOE	Structure of UP1 bound to RNA 5'-AGU-3' Descriptor: ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ... Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2015-03-11 Release date: 2015-06-10 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.92 Å) Cite: The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein. J.Mol.Biol., 427, 2015
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6NRD	hTRiC-hPFD Class4 Descriptor: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... Authors: Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. Deposit date: 2019-01-23 Release date: 2019-06-19 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (8.2 Å) Cite: The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-17 Release date: 2019-06-19 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
4WJO	Crystal Structure of SUMO1 in complex with PML Descriptor: Protein PML, Small ubiquitin-related modifier 1 Authors: Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G. Deposit date: 2014-10-01 Release date: 2014-12-31 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1. Structure, 23, 2015
3AN2	The structure of the centromeric nucleosome containing CENP-A Descriptor: 147 mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Tachiwana, H, Kagawa, W, Shiga, T, Saito, K, Osakabe, A, Hayashi-Takanaka, Y, Park, S.-Y, Kimura, H, Kurumizaka, H. Deposit date: 2010-08-27 Release date: 2011-07-20 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Crystal structure of the human centromeric nucleosome containing CENP-A Nature, 476, 2011
4WJN	Crystal structure of SUMO1 in complex with phosphorylated PML Descriptor: Protein PML, Small ubiquitin-related modifier 1 Authors: Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G. Deposit date: 2014-10-01 Release date: 2014-12-31 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1. Structure, 23, 2015
4WJP	Crystal Structure of SUMO1 in complex with phosphorylated Daxx Descriptor: Daxx, Small ubiquitin-related modifier 1 Authors: Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G. Deposit date: 2014-10-01 Release date: 2014-12-31 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1. Structure, 23, 2015
5EN1	Crystal structure of hnRNPA2B1 in complex with RNA Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') Authors: Wu, B.X, Su, S.C, Ma, J.B. Deposit date: 2015-11-09 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 Nat Commun, 2018
1U1Q	Crystal Structure of UP1 Complexed With d(TTAGGGTTA(DI)GG); A Human Telomeric Repeat Containing Inosine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(OIP)*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1U1P	Crystal Structure of UP1 Complexed With d(TTAGGGTTA 2PR GG); A Human Telomeric Repeat Containing 2-aminopurine Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*(2PR)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1U1M	Crystal Structure of UP1 Complexed With d(TTAGGGTTA 7GU GG); A Human Telomeric Repeat Containing 7-deaza-guanine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(7GU)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1U1R	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(2PR)G); A Human Telomeric Repeat Containing 2-aminopurine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*(2PR)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1U1L	Crystal Structure of UP1 Complexed With d(TTAGGGTT PRN GGG); A Human Telomeric Repeat Containing nebularine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*(PRN)P*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004

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