1VQ6
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4GHI
| Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains in complex with a benzoxadiazole antagonist | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine | Authors: | Scheuermann, T.H, Key, J, Tambar, U.K, Bruick, R.K, Gardner, K.H. | Deposit date: | 2012-08-07 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat.Chem.Biol., 9, 2013
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1VQ5
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1VQ7
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2YY0
| Crystal Structure of MS0802, c-Myc-1 binding protein domain from Homo sapiens | Descriptor: | C-Myc-binding protein | Authors: | Xie, Y, Wang, H, Ihsanawati, K.T, Kishishita, S, Takemoto, C, Shirozu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-27 | Release date: | 2008-04-29 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | crystal structure of c-Myc-1 binding protein domain from Homo sapiens To be Published
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1HL3
| CtBP/BARS in ternary complex with NAD(H) and PIDLSKK peptide | Descriptor: | C-TERMINAL BINDING PROTEIN 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PRO-ILE-ASP-LEU-SER-LYS-LYS PEPTIDE | Authors: | Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M. | Deposit date: | 2003-03-13 | Release date: | 2003-06-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission Embo J., 22, 2003
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1HK9
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2AKG
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2YC0
| FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH R-2-HYDROXYGLUTARATE | Descriptor: | (2R)-2-hydroxypentanedioic acid, FE (II) ION, GLYCEROL, ... | Authors: | Chowdhury, R, Clifton, I.J, Schofield, C.J. | Deposit date: | 2011-03-10 | Release date: | 2011-03-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep., 12, 2011
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1WQ3
| Escherichia coli tyrosyl-tRNA synthetase mutant complexed with 3-iodo-L-tyrosine | Descriptor: | 3-IODO-TYROSINE, Tyrosyl-tRNA synthetase | Authors: | Kobayashi, T, Sakamoto, K, Nureki, O, Takimura, T, Kamata, K, Sekine, R, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-09-20 | Release date: | 2005-01-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion Proc.Natl.Acad.Sci.USA, 102, 2005
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1WRQ
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1WM5
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7JMN
| Tail module of Mediator complex | Descriptor: | MED15, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 16, ... | Authors: | Zhang, H.Q, Chen, D.C. | Deposit date: | 2020-08-02 | Release date: | 2021-03-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Mediator structure and conformation change. Mol.Cell, 81, 2021
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7K3J
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7K3K
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1GWQ
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7K3L
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1WPT
| Crystal Structure of HutP, an RNA binding anti-termination protein | Descriptor: | Hut operon positive regulatory protein | Authors: | Kumarevel, T, Mizuno, H, Kumar, P.K.R. | Deposit date: | 2004-09-13 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis Nucleic Acids Res., 33, 2005
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1H3I
| Crystal structure of the Histone Methyltransferase SET7/9 | Descriptor: | HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE, MAGNESIUM ION | Authors: | Wilson, J.R, Jing, C, Walker, P.A, Martin, S.R, Howell, S.A, Blackburn, G.M, Gamblin, S.J, Xiao, B. | Deposit date: | 2002-09-04 | Release date: | 2002-11-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9 Cell(Cambridge,Mass.), 111, 2002
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1X0S
| Crystal structure of the 13-cis isomer of bacteriorhodopsin | Descriptor: | 2,3-DI-O-PHYTANLY-3-SN-GLYCERO-1-PHOSPHORYL-3'-SN-GLYCEROL-1'-PHOSPHATE, 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, ... | Authors: | Nishikawa, T, Murakami, M, Kouyama, T. | Deposit date: | 2005-03-28 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the 13-cis isomer of bacteriorhodopsin in the dark-adapted state. J.Mol.Biol., 352, 2005
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2XD0
| A processed non-coding RNA regulates a bacterial antiviral system | Descriptor: | TOXI, TOXN | Authors: | Blower, T.R, Pei, X.Y, Short, F.L, Fineran, P.C, Humphreys, D.P, Luisi, B.F, Salmond, G.P.C. | Deposit date: | 2010-04-28 | Release date: | 2011-01-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A processed noncoding RNA regulates an altruistic bacterial antiviral system. Nat. Struct. Mol. Biol., 18, 2011
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7JRI
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7K5J
| Structure of an E1-E2-ubiquitin thioester mimetic | Descriptor: | ADENOSINE MONOPHOSPHATE, Ubiquitin, Ubiquitin-activating enzyme E1 1, ... | Authors: | Yuan, L, Lv, Z, Olsen, S.K. | Deposit date: | 2020-09-16 | Release date: | 2021-04-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification. Nat Commun, 12, 2021
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8U77
| Crystal structure of Taf14 in complex with Yng1 | Descriptor: | Protein YNG1, Transcription initiation factor TFIID subunit 14 | Authors: | Nguyen, M.C, Wei, P.C, Zhang, G.Y, Kutateladze, T.G. | Deposit date: | 2023-09-14 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Molecular insight into interactions between the Taf14, Yng1 and Sas3 subunits of the NuA3 complex. Nat Commun, 15, 2024
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6B1C
| Macrophage Migration Inhibitory Factor in complex with a Naphthyridinone Inhibitor (4a) | Descriptor: | 2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one, Macrophage migration inhibitory factor, SULFATE ION | Authors: | Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. | Deposit date: | 2017-09-18 | Release date: | 2018-01-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.163 Å) | Cite: | Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor. ACS Med Chem Lett, 8, 2017
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