7K5J

Structure of an E1-E2-ubiquitin thioester mimetic

Summary for 7K5J

Entry DOI	10.2210/pdb7k5j/pdb
Descriptor	Ubiquitin, Ubiquitin-activating enzyme E1 1, Ubiquitin-conjugating enzyme E2-34 kDa, ... (4 entities in total)
Functional Keywords	conformational change, adenylation, thioester transfer, transthioesterification, atp-binding, ubiquitin e2-binding, ubiquitination, signaling protein
Biological source	Triticum aestivum (Wheat) More
Total number of polymer chains	24
Total formula weight	1169489.80
Authors	Yuan, L.,Lv, Z.,Olsen, S.K. (deposition date: 2020-09-16, release date: 2021-04-28, Last modification date: 2023-10-18)
Primary citation	Yuan, L.,Lv, Z.,Adams, M.J.,Olsen, S.K. Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification. Nat Commun, 12:2370-2370, 2021 Cited by PubMed: 33888705 DOI: 10.1038/s41467-021-22598-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.42 Å)

Structure validation