8TL2
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![BU of 8tl2 by Molmil](/molmil-images/mine/8tl2) | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-c.01 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | Deposit date: | 2023-07-26 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques. To Be Published
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8TL3
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![BU of 8tl3 by Molmil](/molmil-images/mine/8tl3) | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-d.01 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP glycoprotein gp120, ... | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | Deposit date: | 2023-07-26 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques. To Be Published
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8TL4
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![BU of 8tl4 by Molmil](/molmil-images/mine/8tl4) | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-e.01 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | Deposit date: | 2023-07-26 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques. To Be Published
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8TL5
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![BU of 8tl5 by Molmil](/molmil-images/mine/8tl5) | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | Deposit date: | 2023-07-26 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques. To Be Published
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8TNG
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![BU of 8tng by Molmil](/molmil-images/mine/8tng) | |
8TNH
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![BU of 8tnh by Molmil](/molmil-images/mine/8tnh) | |
8TNI
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![BU of 8tni by Molmil](/molmil-images/mine/8tni) | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP gp120, ... | Authors: | Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D, Xu, J. | Deposit date: | 2023-08-01 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex To Be Published
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8TNU
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![BU of 8tnu by Molmil](/molmil-images/mine/8tnu) | Cryo-EM structure of TRNM-b*01 Fab in complex with HIV-1 Env trimer BG505.DS SOSIP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | Authors: | Roark, R.S, Morano, N.C, Shapiro, L.S, Kwong, P.D. | Deposit date: | 2023-08-02 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques To Be Published
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8TO7
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![BU of 8to7 by Molmil](/molmil-images/mine/8to7) | Cryo-EM structure of HERH-b*01 Fab in complex with HIV-1 Env trimer BG505.DS SOSIP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HERH-b*01 heavy chain, ... | Authors: | Roark, R.S, Hoyt, F, Hansen, B, Fischer, E, Shapiro, L.S, Kwong, P.D. | Deposit date: | 2023-08-03 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques To Be Published
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8TOP
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![BU of 8top by Molmil](/molmil-images/mine/8top) | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP glycoprotein gp41, ... | Authors: | Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D. | Deposit date: | 2023-08-03 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide To Be Published
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8TOX
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![BU of 8tox by Molmil](/molmil-images/mine/8tox) | |
8TQ1
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![BU of 8tq1 by Molmil](/molmil-images/mine/8tq1) | |
8TR3
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![BU of 8tr3 by Molmil](/molmil-images/mine/8tr3) | Cryo-EM structure of HmAb64 scFv in complex with CNE40 SOSIP trimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CNE40 SOSIP Envelope glycoprotein gp120, ... | Authors: | Chan, K.-W, Kong, X.P. | Deposit date: | 2023-08-09 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains. Nat Commun, 15, 2024
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8TTW
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![BU of 8ttw by Molmil](/molmil-images/mine/8ttw) | Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074 | Descriptor: | 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Tolbert, W.D, Pozharski, E, Pazgier, M. | Deposit date: | 2023-08-15 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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8VFV
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![BU of 8vfv by Molmil](/molmil-images/mine/8vfv) | HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B16_d77.5 mouse Fab heavy chain Fv, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2023-12-22 | Release date: | 2024-05-15 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies. Science, 384, 2024
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9BER
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![BU of 9ber by Molmil](/molmil-images/mine/9ber) | Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2024-04-16 | Release date: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43, 2024
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9BF6
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![BU of 9bf6 by Molmil](/molmil-images/mine/9bf6) | |