8G3D
 
 | | 48-nm doublet microtubule from Tetrahymena thermophila strain K40R | | 分子名称: | B2B3_fMIP, B5B6_fMIP, CFAM166A, ... | | 著者 | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | | 登録日 | 2023-02-07 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
Nat Commun, 14, 2023
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8GZW
 | | Klebsiella pneumoniae FtsZ complexed with monobody (P21) | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Monobody | | 著者 | Matsumura, H, Yoshizawa, T, Fujita, J, Tanaka, S, Amesaka, H. | | 登録日 | 2022-09-27 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
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8GZV
 | | Klebsiella pneumoniae FtsZ complexed with monobody (P212121) | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Monobody | | 著者 | Matsumura, H, Yoshizawa, T, Fujita, J, Tanaka, S, Amesaka, H. | | 登録日 | 2022-09-27 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
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8GZX
 | | Escherichia coli FtsZ complexed with monobody (P212121) | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Monobody | | 著者 | Matsumura, H, Yoshizawa, T, Fujita, J, Tanaka, S, Amesaka, H. | | 登録日 | 2022-09-27 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
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8GZY
 | | Escherichia coli FtsZ complexed with monobody (P21) | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Monobody | | 著者 | Matsumura, H, Yoshizawa, T, Fujita, J, Tanaka, S, Amesaka, H. | | 登録日 | 2022-09-27 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
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8H1O
 | | Cryo-EM structure of KpFtsZ-monobody double helical tube | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Mb(Ec/KpFtsZ_S1) | | 著者 | Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H. | | 登録日 | 2022-10-03 | | 公開日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
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8GRW
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8HUH
 | | Crystal structure of T2R-TTL-3a complex | | 分子名称: | 2-(1-methylindol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1~{H}-imidazo[4,5-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y.X, Chen, J.J. | | 登録日 | 2022-12-23 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of T2R-TTL-3a complex
To Be Published
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8HTB
 | | Staphylococcus aureus FtsZ 12-316 complexed with TXH9179 | | 分子名称: | 3-[(6-ethynyl-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ... | | 著者 | Bryan, E, Ferrer-Gonzalez, E, Sagong, H.Y, Fujita, J, Mark, L, Kaul, M, LaVoie, E.J, Matsumura, H, Pilch, D.S. | | 登録日 | 2022-12-21 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural and Antibacterial Characterization of a New Benzamide FtsZ Inhibitor with Superior Bactericidal Activity and In Vivo Efficacy Against Multidrug-Resistant Staphylococcus aureus.
Acs Chem.Biol., 18, 2023
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8IBN
 | | Cryo-EM structure of KpFtsZ single filament | | 分子名称: | Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, POTASSIUM ION | | 著者 | Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hibino, K, Konishi, T, Kato, Y, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H. | | 登録日 | 2023-02-10 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
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8IXB
 | | GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXD
 | | GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXG
 | | GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXE
 | | GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXA
 | | GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXF
 | | GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin non-seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8I7O
 | | In situ structure of axonemal doublet microtubules in mouse sperm with 16-nm repeat | | 分子名称: | Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 276, ... | | 著者 | Zhu, Y, Yin, G.L, Tai, L.H, Sun, F. | | 登録日 | 2023-02-01 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | In-cell structural insight into the stability of sperm microtubule doublet.
Cell Discov, 9, 2023
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8I7R
 | | In situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat | | 分子名称: | Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | | 著者 | Zhu, Y, Yin, G.L, Tai, L.H, Sun, F. | | 登録日 | 2023-02-02 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | In-cell structural insight into the stability of sperm microtubule doublet.
Cell Discov, 9, 2023
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6K9V
 | | Crystal structure of tubulin in complex with inhibitor D64 | | 分子名称: | (5-methoxy-1H-indol-2-yl)-phenyl-methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Yu, Y, Chen, Q. | | 登録日 | 2019-06-18 | | 公開日 | 2019-08-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.543 Å) | | 主引用文献 | Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
Febs Lett., 594, 2020
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6KIQ
 | | Complex of yeast cytoplasmic dynein MTBD-High and MT with DTT | | 分子名称: | Alpha tubulin, Dynein heavy chain, cytoplasmic, ... | | 著者 | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | | 登録日 | 2019-07-19 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
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6KIO
 | | Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT | | 分子名称: | Dynein heavy chain, cytoplasmic, Tubulin alpha-1A chain, ... | | 著者 | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | | 登録日 | 2019-07-19 | | 公開日 | 2020-03-04 | | 最終更新日 | 2020-03-11 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
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6KNZ
 | | Crystal structure of T2R-TTL-KXO1 complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide, CALCIUM ION, ... | | 著者 | Chen, Q, Yu, Y. | | 登録日 | 2019-08-07 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.475 Å) | | 主引用文献 | Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of beta-tubulin explains KXO1's low clinical toxicity.
J.Biol.Chem., 294, 2019
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6KVQ
 | | S. aureus FtsZ in complex with BOFP (compound 3) | | 分子名称: | CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S. | | 登録日 | 2019-09-05 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.
Sci Rep, 9, 2019
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6KPP
 | | BNC105 in complex with tubulin | | 分子名称: | (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, T, Wu, C, Pu, D. | | 登録日 | 2019-08-15 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.74524117 Å) | | 主引用文献 | Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design.
Biochem.Biophys.Res.Commun., 2020
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6KVP
 | | S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2) | | 分子名称: | 3-[(1R)-1-[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]ethoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ... | | 著者 | Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S. | | 登録日 | 2019-09-05 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.
Sci Rep, 9, 2019
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