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8KAL
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BU of 8kal by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 17nt target DNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
2TRA
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BU of 2tra by Molmil
RESTRAINED REFINEMENT OF TWO CRYSTALLINE FORMS OF YEAST ASPARTIC ACID AND PHENYLALANINE TRANSFER RNA CRYSTALS
Descriptor: MAGNESIUM ION, SPERMINE, TRNAASP
Authors:Westhof, E, Dumas, P, Moras, D.
Deposit date:1987-11-06
Release date:1987-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals.
Acta Crystallogr.,Sect.A, 44, 1988
5TPY
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BU of 5tpy by Molmil
Crystal structure of an exonuclease resistant RNA from Zika virus
Descriptor: HEXANE-1,6-DIOL, MAGNESIUM ION, RNA (71-MER)
Authors:Akiyama, B.M, Laurence, H.M, Massey, A.R, Costantino, D.A, Xie, X, Yang, Y, Shi, P.-Y, Nix, J.C, Beckham, J.D, Kieft, J.S.
Deposit date:2016-10-21
Release date:2016-12-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease.
Science, 354, 2016
8R3Z
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BU of 8r3z by Molmil
Cryo-EM structure of the Asgard archaeal Argonaute HrAgo1 bound to a guide RNA
Descriptor: HrAgo1, MAGNESIUM ION, RNA (5'-R(P*UP*GP*AP*GP*GP*U*(MG))-3')
Authors:Finocchio, G, Swarts, D, Jinek, M.
Deposit date:2023-11-10
Release date:2024-06-19
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:RNA-guided RNA silencing by an Asgard archaeal Argonaute.
Nat Commun, 15, 2024
6G63
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BU of 6g63 by Molmil
RNase E in complex with sRNA RrpA
Descriptor: RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), Ribonuclease E, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Bandyra, K.B, Luisi, B.F.
Deposit date:2018-03-31
Release date:2018-10-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
Mol. Cell, 72, 2018
7V0F
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BU of 7v0f by Molmil
Structure of 6-carboxy-5,6,7,8-tetrahydropterin synthase paralog QueD2 from Acinetobacter baumannii
Descriptor: 1,2-ETHANEDIOL, 6-carboxy-5,6,7,8-tetrahydropterin synthase, DI(HYDROXYETHYL)ETHER, ...
Authors:Jordan, M.R, Gonzalez-Gutierrez, G, Giedroc, D.P.
Deposit date:2022-05-10
Release date:2022-12-07
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Metal retention and replacement in QueD2 protect queuosine-tRNA biosynthesis in metal-starved Acinetobacter baumannii.
Proc.Natl.Acad.Sci.USA, 119, 2022
1FYO
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BU of 1fyo by Molmil
EUKARYOTIC DECODING REGION A-SITE RNA
Descriptor: FRAGMENT OF 18S RIBOSOMAL RNA
Authors:Lynch, S.R, Puglisi, J.D.
Deposit date:2000-10-02
Release date:2001-03-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of a eukaryotic decoding region A-site RNA.
J.Mol.Biol., 306, 2001
1A2P
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BU of 1a2p by Molmil
BARNASE WILDTYPE STRUCTURE AT 1.5 ANGSTROMS RESOLUTION
Descriptor: BARNASE, ZINC ION
Authors:Martin, C, Richard, V, Salem, M, Hartley, R.W, Mauguen, Y.
Deposit date:1998-01-07
Release date:1998-04-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Refinement and structural analysis of barnase at 1.5 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1AXP
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BU of 1axp by Molmil
DNA DUPLEX CONTAINING A PURINE-RICH STRAND, NMR, 6 STRUCTURES
Descriptor: DNA (D(GAAGAGAAGC)(DOT)D(GCTTCTCTTC))
Authors:Gyi, J.I, Lane, A.N, Conn, G.L, Brown, T.
Deposit date:1997-10-17
Release date:1998-04-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry, 37, 1998
6XMG
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BU of 6xmg by Molmil
Cryo-EM structure of Cas12g ternary complex
Descriptor: CRISPR-Cas, RNA (130-MER), RNA (5'-R(P*UP*UP*AP*AP*UP*GP*CP*GP*GP*UP*AP*GP*UP*UP*UP*AP*UP*CP*AP*CP*AP*GP*UP*U)-3'), ...
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2020-06-30
Release date:2021-01-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM structure of the RNA-guided ribonuclease Cas12g.
Nat.Chem.Biol., 17, 2021
5J1O
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BU of 5j1o by Molmil
Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat
Descriptor: Apical region (29mer) of the HIV-1 TAR element, Cyclic peptide mimetic of Tat
Authors:Borkar, A.N, Bardaro, M.F, Varani, G, Vendruscolo, M.
Deposit date:2016-03-29
Release date:2016-06-08
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
3WBM
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BU of 3wbm by Molmil
Crystal Structure of protein-RNA complex
Descriptor: DNA/RNA-binding protein Alba 1, RNA (25-MER)
Authors:Ding, J, Wang, D.C.
Deposit date:2013-05-20
Release date:2013-12-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural insights into RNA binding by Ssh10b, a member of the highly conserved Sac10b protein family in Archaea.
J.Biol.Chem., 289, 2014
7MLW
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BU of 7mlw by Molmil
Burkholderia sp. TJI49 Guanidine-I riboswitch
Descriptor: GUANIDINE, Guanidine-I riboswitch, MAGNESIUM ION, ...
Authors:Trachman, R.J, Ferre-D'Amare, A.R.
Deposit date:2021-04-29
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An uncommon [K + (Mg 2+ ) 2 ] metal ion triad imparts stability and selectivity to the Guanidine-I riboswitch.
Rna, 27, 2021
4AL5
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BU of 4al5 by Molmil
Crystal structure of the Csy4-crRNA product complex
Descriptor: 5'-R(*UP*UP*CP*AP*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP *GP*GP*CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE, GLYCEROL
Authors:Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
Deposit date:2012-03-02
Release date:2012-06-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
4TNA
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BU of 4tna by Molmil
FURTHER REFINEMENT OF THE STRUCTURE OF YEAST T-RNA-PHE
Descriptor: MAGNESIUM ION, TRNAPHE
Authors:Hingerty, B.E, Brown, R.S, Jack, A.
Deposit date:1978-04-12
Release date:1978-04-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Further refinement of the structure of yeast tRNAPhe.
J.Mol.Biol., 124, 1978
5XC6
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BU of 5xc6 by Molmil
Dengue Virus 4 NS3 Helicase in complex with SSRNA SLA12
Descriptor: NS3 Helicase, PHOSPHATE ION, RNA (5'-R(*AP*GP*UP*UP*GP*UP*UP*AP*GP*UP*CP*U)-3')
Authors:Swarbrick, C.M.D, Basavannacharya, C, Chan, K.W.K, Chan, S.A, Singh, D, Wei, N, Phoo, W.W, Luo, D, Lescar, J, Vasudevan, S.G.
Deposit date:2017-03-22
Release date:2017-11-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
Nucleic Acids Res., 45, 2017
2I7V
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BU of 2i7v by Molmil
Structure of Human CPSF-73
Descriptor: Cleavage and polyadenylation specificity factor 73 kDa subunit, SULFATE ION, ZINC ION
Authors:Mandel, C.R, Zhang, H, Tong, L.
Deposit date:2006-08-31
Release date:2007-01-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
165D
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BU of 165d by Molmil
THE STRUCTURE OF A MISPAIRED RNA DOUBLE HELIX AT 1.6 ANGSTROMS RESOLUTION AND IMPLICATIONS FOR THE PREDICTION OF RNA SECONDARY STRUCTURE
Descriptor: DNA/RNA (5'-R(*GP*CP*UP*UP*CP*GP*GP*CP*)-D(*(BRU))-3'), RHODIUM HEXAMINE ION
Authors:Cruse, W, Saludjian, P, Biala, E, Strazewski, P, Prange, T, Kennard, O.
Deposit date:1994-03-21
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of a mispaired RNA double helix at 1.6-A resolution and implications for the prediction of RNA secondary structure.
Proc.Natl.Acad.Sci.USA, 91, 1994
2I7T
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BU of 2i7t by Molmil
Structure of human CPSF-73
Descriptor: Cleavage and polyadenylation specificity factor 73 kDa subunit, SULFATE ION, ZINC ION
Authors:Mandel, C.R, Zhang, H, Tong, L.
Deposit date:2006-08-31
Release date:2007-01-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
3QRR
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BU of 3qrr by Molmil
Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex
Descriptor: Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*(23G))-3')
Authors:Schellenberg, M.J, Gesner, E.G, Garside, E.L, MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.099 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
4GHA
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BU of 4gha by Molmil
Crystal structure of Marburg virus VP35 RNA binding domain bound to 12-bp dsRNA
Descriptor: Polymerase cofactor VP35, RNA (5'-R(*CP*UP*AP*GP*AP*CP*GP*UP*CP*UP*AP*G)-3')
Authors:Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O.
Deposit date:2012-08-07
Release date:2012-08-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism.
Plos Pathog., 8, 2012
3QRQ
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BU of 3qrq by Molmil
Structure of Thermus Thermophilus Cse3 bound to an RNA representing a pre-cleavage complex
Descriptor: Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*GP*A)-3')
Authors:Schellenberg, M.J, Gesner, E.G, Garside, E.L, MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
3QRP
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BU of 3qrp by Molmil
Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product mimic complex
Descriptor: Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*(PGP))-3'), RNA (5'-R(P*(U5P)P*GP*UP*GP*GP*GP*G)-3'), ...
Authors:Schellenberg, M.J, Gesner, E.M, Garside, E.L, MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.352 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
168D
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BU of 168d by Molmil
STABILIZING EFFECTS OF THE RNA 2'-SUBSTITUENT: CRYSTAL STRUCTURE OF AN OLIGODEOXYNUCLEOTIDE DUPLEX CONTAINING 2'-O-METHYLATED ADENOSINES
Descriptor: DNA/RNA (5'-D(*GP*CP*GP*TP*)-R(*(A2M)P*)-D(*TP*AP*CP*GP*C)-3')
Authors:Lubini, P, Zuercher, W, Egli, M.
Deposit date:1994-04-08
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Stabilizing effects of the RNA 2'-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2'-O-methylated adenosines.
Chem.Biol., 1, 1994
2EC0
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BU of 2ec0 by Molmil
RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP
Descriptor: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2007-02-09
Release date:2007-06-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007

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