8XVS

RNA polymerase II elongation complex with downstream nucleosome extracted from human nuclei

Summary for 8XVS

• Entry DOI: 10.2210/pdb8xvs/pdb
• EMDB information: 38717
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, ... (21 entities in total)
• Functional Keywords: rna polymerase, complex, nucleus, nucleosome, transcription-dna-rna complex, transcription/dna/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 23
• Total formula weight: 733055.93

Authors

Kujirai, T.,Kato, J.,Yamamoto, K.,Hirai, S.,Negishi, L.,Ogasawara, M.,Takizawa, Y.,Kurumizaka, H. (deposition date: 2024-01-15, release date: 2025-05-07)

• Primary citation: Kujirai, T.,Kato, J.,Yamamoto, K.,Hirai, S.,Fujii, T.,Maehara, K.,Harada, A.,Negishi, L.,Ogasawara, M.,Yamaguchi, Y.,Ohkawa, Y.,Takizawa, Y.,Kurumizaka, H.; Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.1 Å)