6IS0

Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA

Summary for 6IS0

Entry DOI	10.2210/pdb6is0/pdb
Descriptor	PDX1 C-terminal-inhibiting factor 1, m7G-capped RNA, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total)
Functional Keywords	rna methylation, methyltransferase, m6a, n6-methyladenosine, transferase-rna complex, transferase/rna
Biological source	Danio rerio (Zebrafish) More
Total number of polymer chains	2
Total formula weight	60027.73
Authors	Hirano, S.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2018-11-15, release date: 2018-12-05, Last modification date: 2024-03-06)
Primary citation	Akichika, S.,Hirano, S.,Shichino, Y.,Suzuki, T.,Nishimasu, H.,Ishitani, R.,Sugita, A.,Hirose, Y.,Iwasaki, S.,Nureki, O.,Suzuki, T. Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363:-, 2019 Cited by PubMed: 30467178 DOI: 10.1126/science.aav0080 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation