4GX2
| GsuK channel bound to NAD | Descriptor: | CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
|
|
4GX1
| Crystal structure of the GsuK bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
|
|
6U6H
| Calcium-bound MthK open-inactivated state 3 | Descriptor: | Calcium-gated potassium channel MthK | Authors: | Chen, F, Crina, N. | Deposit date: | 2019-08-29 | Release date: | 2020-04-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
|
|
6U5R
| Calcium-bound MthK closed state | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
|
|
6U5P
| Calcium-bound MthK gating ring state 1 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
|
|
2H8P
| Structure of a K channel with an amide to ester substitution in the selectivity filter | Descriptor: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB heavy chain, FAB light chain, ... | Authors: | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | Deposit date: | 2006-06-07 | Release date: | 2006-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
|
|
3RBZ
| MthK channel, Ca2+-bound | Descriptor: | CALCIUM ION, Calcium-gated potassium channel mthK | Authors: | Taylor, A.B, Parfenova, L.V, Rothberg, B.S. | Deposit date: | 2011-03-30 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of multiple Ca2+-binding sites in a K+ channel RCK domain Proc.Natl.Acad.Sci.USA, 2011
|
|
2HG5
| Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter | Descriptor: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, CESIUM ION, FAB HEAVY CHAIN, ... | Authors: | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | Deposit date: | 2006-06-26 | Release date: | 2006-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
|
|
6CNN
| |
6CJT
| Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cGMP | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CYCLIC GUANOSINE MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel | Authors: | Nimigean, C.M, Rheinberger, J. | Deposit date: | 2018-02-26 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures. Elife, 7, 2018
|
|
6CNO
| |
6CNM
| Cryo-EM structure of the human SK4/calmodulin channel complex | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calmodulin-1, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Lee, C.H, MacKinnon, R. | Deposit date: | 2018-03-08 | Release date: | 2018-05-02 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Science, 360, 2018
|
|
6CJU
| Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel | Authors: | Nimigean, C.M, Rheinberger, J. | Deposit date: | 2018-02-26 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures. Elife, 7, 2018
|
|
6CJQ
| Structure of the SthK cyclic nucleotide-gated potassium channel | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, SthK cyclic nucleotide-gated potassium channel | Authors: | Nimigean, C.M, Rheinberger, J. | Deposit date: | 2018-02-26 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures. Elife, 7, 2018
|
|
5BKI
| Blocker-free closed MthK channel in nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CADMIUM ION, Calcium-gated potassium channel MthK, ... | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2021-03-19 | Release date: | 2022-09-21 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 2023
|
|
5BKJ
| TPeA-bound closed MthK channel in nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1-(tripentyl-$l^{4}-azanyl)pentane, Calcium-gated potassium channel MthK, ... | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2021-03-19 | Release date: | 2022-09-21 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 2023
|
|
5BKK
| bbTBA-bound closed MthK channel in nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (~{R})-phenyl-[4-[(tributyl-$l^{4}-azanyl)methyl]phenyl]methanol, Calcium-gated potassium channel MthK, ... | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2021-03-19 | Release date: | 2022-09-21 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 2023
|
|
8DJB
| MthK-A90L mutant in closed state with 0 Ca2+ | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | Authors: | Agarwal, S, Nimigean, C.M. | Deposit date: | 2022-06-30 | Release date: | 2023-07-05 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 20, 2024
|
|
3FB6
| KcsA Potassium channel in the partially open state with 16 A opening at T112 | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-18 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | KcsA Potassium channel in the partially open state with 16 A opening at T112 TO BE PUBLISHED
|
|
3F7Y
| KcsA Potassium channel in the partially open state with 17 A opening at T112 | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-10 | Release date: | 2010-05-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | KcsA Potassium channel in the partially open state with 17 A opening at T112 TO BE PUBLISHED
|
|
3F7V
| KcsA Potassium channel in the open-inactivated state with 23 A opening at T112 | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment Heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-10 | Release date: | 2010-05-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112 TO BE PUBLISHED
|
|
6U68
| |
6U6D
| MthK closed state with EDTA | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | Authors: | Fan, C, Rheinberger, J, Nimigean, C.M. | Deposit date: | 2019-08-29 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
|
|
6U5N
| Calcium-bound MthK gating ring state 2 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
|
|
6U6E
| |