6CNN
Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state I
Summary for 6CNN
| Entry DOI | 10.2210/pdb6cnn/pdb |
| EMDB information | 7537 7538 7539 |
| Descriptor | Intermediate conductance calcium-activated potassium channel protein 4, Calmodulin-1, POTASSIUM ION, ... (6 entities in total) |
| Functional Keywords | ion channel, neuroscience, calmodulin, membrane protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 266206.72 |
| Authors | Lee, C.H.,MacKinnon, R. (deposition date: 2018-03-08, release date: 2018-05-02, Last modification date: 2024-03-13) |
| Primary citation | Lee, C.H.,MacKinnon, R. Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Science, 360:508-513, 2018 Cited by PubMed: 29724949DOI: 10.1126/science.aas9466 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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