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6CNN

Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state I

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Intermediate conductance calcium-activated potassium channel protein 4polymer42747758.54UniProt (O15554)
Pfam (PF03530)
Pfam (PF07885)
Pfam (PF02888)
Homo sapiens (Human)SK4 channel, SKCa4, IKCa1, IK1, KCa3.1, KCa4, Putative Gardos channel
2E, F, G, H
(E, F, G, H)
Calmodulin-1polymer14916852.54UniProt (P0DP23)
Pfam (PF13499)
Homo sapiens (Human)
3I, J, K, L
(A)
POTASSIUM IONnon-polymer39.14Chemie (K)
4M, P, S, V
(A, B, C, D)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.14Chemie (POV)
5N, O, Q, R, T...
(A, B, C, D)
DODECYL-BETA-D-MALTOSIDEnon-polymer510.68Chemie (LMT)
6AA, BA, CA, DA, EA...
(E, F, G, H)
CALCIUM IONnon-polymer40.112Chemie (CA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight258444.2
Non-Polymers*Number of molecules28
Total formula weight7762.6
All*Total formula weight266206.7
*Water molecules are not included.

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PDB entries from 2025-06-25

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