6ICZ
 
 | | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | | 登録日 | 2018-09-07 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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6HPJ
 | | Structure of human SRSF1 RRM1 bound to AACAAA RNA | | 分子名称: | Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 1, RNA (5'-R(*AP*AP*CP*AP*AP*A)-3') | | 著者 | Allain, F.T.H, Clery, A. | | 登録日 | 2018-09-21 | | 公開日 | 2020-11-18 | | 最終更新日 | 2021-06-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing.
Nat Commun, 12, 2021
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6HIP
 | | Structure of SPF45 UHM bound to HIV-1 Rev ULM | | 分子名称: | HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... | | 著者 | Pabis, M, Corsini, L, Sattler, M. | | 登録日 | 2018-08-30 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
Nucleic Acids Res., 47, 2019
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6GX6
 | | Crystal structure of IMP3 RRM12 in complex with RNA (ACAC) | | 分子名称: | 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3, PHOSPHATE ION, ... | | 著者 | Jia, M, Gut, H, Chao, A.J. | | 登録日 | 2018-06-26 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
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6GSN
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6GSM
 | | Structure of a partial yeast 48S preinitiation complex in open conformation. | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | | 著者 | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2018-06-14 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
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6GML
 | | Structure of paused transcription complex Pol II-DSIF-NELF | | 分子名称: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | | 登録日 | 2018-05-27 | | 公開日 | 2018-09-05 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
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6GD3
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6GD2
 | | Structure of HuR RRM3 in complex with RNA | | 分子名称: | ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3') | | 著者 | Pabis, M, Sattler, M. | | 登録日 | 2018-04-21 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
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6GD1
 | | Structure of HuR RRM3 | | 分子名称: | SODIUM ION, Thioredoxin 1,ELAV-like protein 1 | | 著者 | Pabis, M, Sattler, M. | | 登録日 | 2018-04-21 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
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6GC5
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6GBM
 | | Solution structure of FUS-RRM bound to stem-loop RNA | | 分子名称: | RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS | | 著者 | Loughlin, F.E, Allain, F.H.-T. | | 登録日 | 2018-04-15 | | 公開日 | 2019-02-20 | | 最終更新日 | 2019-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell, 73, 2019
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6G90
 | | Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ... | | 著者 | Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K. | | 登録日 | 2018-04-10 | | 公開日 | 2018-08-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Prespliceosome structure provides insights into spliceosome assembly and regulation.
Nature, 559, 2018
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6G2K
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6FYY
 | | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | | 著者 | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2018-03-12 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
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6FYX
 | | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | | 著者 | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2018-03-12 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
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6FQR
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6FQ1
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6FF7
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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6FF4
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-08-29 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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6FEC
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6F4J
 | | Crystal structure of Drosophila melanogaster SNF/U2A' complex | | 分子名称: | POLYETHYLENE GLYCOL (N=34), Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... | | 著者 | Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. | | 登録日 | 2017-11-29 | | 公開日 | 2018-06-20 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
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6F4I
 | | Crystal structure of Drosophila melanogaster SNF | | 分子名称: | U1 small nuclear ribonucleoprotein A | | 著者 | Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. | | 登録日 | 2017-11-29 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
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6F4H
 | | Crystal structure of the Drosophila melanogaster SNF/U1-SL2 complex | | 分子名称: | CITRATE ANION, U1 small nuclear ribonucleoprotein A, U1-SL2 | | 著者 | Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. | | 登録日 | 2017-11-29 | | 公開日 | 2018-06-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
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6F4G
 | | 'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex | | 分子名称: | CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... | | 著者 | Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. | | 登録日 | 2017-11-29 | | 公開日 | 2018-06-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
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