PDB: 61302 resultsInfo pagesStatus searchChemie searchBIRD

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4QVC	E.coli Hfq in complex with RNA Aus Descriptor: RNA (5'-R(*AP*U*AP*AP*CP*UP*A)-3'), RNA-binding protein Hfq Authors: Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y. Deposit date: 2014-07-14 Release date: 2015-05-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq Nucleic Acids Res., 43, 2015
4YE2	The 1.35 structure of a viral RNase L antagonist reveals basis for the 2'-5'-oligoadenylate binding and enzyme activity. Descriptor: ADENOSINE-2'-5'-DIPHOSPHATE, Capping enzyme protein, SULFATE ION Authors: Hu, L, Sankaran, B, Prasad, B.V.V. Deposit date: 2015-02-23 Release date: 2015-04-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.098 Å) Cite: Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist. J.Virol., 89, 2015
6ROL	Structure of IMP2 KH34 domains Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin-like growth factor 2 mRNA-binding protein 2, ... Authors: Bhaskar, V, Biswas, J, Singer, R.H, Chao, J.A. Deposit date: 2019-05-13 Release date: 2019-10-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structural basis for RNA selectivity by the IMP family of RNA-binding proteins. Nat Commun, 10, 2019
7NXX	Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). Descriptor: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... Authors: Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C. Deposit date: 2021-03-19 Release date: 2022-09-28 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.189 Å) Cite: Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1 To Be Published
5KDX	IMPa metallopeptidase in complex with T-antigen Descriptor: 1,2-ETHANEDIOL, Metallopeptidase, PHOSPHATE ION, ... Authors: Noach, I, Boraston, A.B. Deposit date: 2016-06-08 Release date: 2017-01-11 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Recognition of protein-linked glycans as a determinant of peptidase activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5KD8	BT_4244 metallopeptidase in complex with Tn antigen. Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Metallopeptidase, NICKEL (II) ION, ... Authors: Noach, I, Boraston, A.B. Deposit date: 2016-06-07 Release date: 2017-01-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Recognition of protein-linked glycans as a determinant of peptidase activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7NOZ	Structure of the nanobody stablized properdin bound alternative pathway proconvertase C3b:FB:FP Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 alpha chain, Complement C3 beta chain, ... Authors: Lorenzen, J, Pedersen, D.V, Andersen, G.R. Deposit date: 2021-02-26 Release date: 2022-07-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Structure determination of an unstable macromolecular complex enabled by nanobody-peptide bridging. Protein Sci., 31, 2022
6ZM2	Crystal structure of the DEAH-box ATPase Prp2 in complex with ADP-BeF3 and ssRNA Descriptor: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Hamann, F, Ficner, R. Deposit date: 2020-07-01 Release date: 2021-04-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases. Acta Crystallogr D Struct Biol, 77, 2021
5KDV	IMPa metallopeptidase from Pseudomonas aeruginosa Descriptor: 1,2-ETHANEDIOL, Metallopeptidase, SULFATE ION, ... Authors: Noach, I, Boraston, A.B. Deposit date: 2016-06-08 Release date: 2017-01-11 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Recognition of protein-linked glycans as a determinant of peptidase activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6AVY	Crystal structure of Zea mays acyl-protein thioesterase 2 Descriptor: Acyl-protein thioesterase 2 Authors: Burger, M, Willige, B.C, Chory, J. Deposit date: 2017-09-04 Release date: 2017-12-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.24 Å) Cite: A hydrophobic anchor mechanism defines a deacetylase family that suppresses host response against YopJ effectors. Nat Commun, 8, 2017
7A9I	Crystal structure of Coronafacic Acid Ligase from Pectobacterium brasiliense Descriptor: 6-ethyl-1-oxidanylidene-indene-4-carboxylic acid, Cfl, PHOSPHATE ION Authors: Levy, C.W. Deposit date: 2020-09-02 Release date: 2021-05-05 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery, characterization and engineering of ligases for amide synthesis. Nature, 593, 2021
7NMO	Crystal structure of beta-2-microglobulin D76A mutant Descriptor: Beta-2-microglobulin Authors: Guthertz, N. Deposit date: 2021-02-23 Release date: 2022-08-03 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
7NMR	Crystal structure of beta-2-microglobulin D76S mutant Descriptor: Beta-2-microglobulin, GLYCEROL Authors: Guthertz, N. Deposit date: 2021-02-23 Release date: 2022-08-03 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.15 Å) Cite: The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
6U5M	Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction Descriptor: 5-bromo-2-hydroxy-N-[3-(methylsulfonyl)-5-(pentafluoro-lambda~6~-sulfanyl)phenyl]benzene-1-sulfonamide, WD repeat-containing protein 5 Authors: Zhao, B, Wang, F. Deposit date: 2019-08-28 Release date: 2019-12-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction. J.Med.Chem., 62, 2019
6I50	Structure of Eiger TNF from S. frugiperda Descriptor: SFRICE_029225 Authors: Bertinelli, M, Paesen, G.C, Grimes, J.M, Renner, M. Deposit date: 2018-11-12 Release date: 2019-08-14 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.69 Å) Cite: High-resolution crystal structure of arthropod Eiger TNF suggests a mode of receptor engagement and altered surface charge within endosomes. Commun Biol, 2, 2019
7A9J	Crystal structure of the R395G mutant form of Coronafacic Acid Ligase from Pectobacterium brasiliense Descriptor: 6-ethyl-1-oxidanylidene-indene-4-carboxylic acid, Cfl, PHOSPHATE ION Authors: Levy, C.W. Deposit date: 2020-09-02 Release date: 2021-05-05 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Discovery, characterization and engineering of ligases for amide synthesis. Nature, 593, 2021
6AR1	Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Nat)) Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... Authors: Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. Deposit date: 2017-08-21 Release date: 2017-11-29 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Mol. Cell, 68, 2017
7NMT	Crystal structure of beta-2-microglobulin D76G mutant Descriptor: Beta-2-microglobulin Authors: Guthertz, N. Deposit date: 2021-02-23 Release date: 2022-08-03 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
7NMC	Crystal structure of beta-2-microglobulin D76E mutant Descriptor: Beta-2-microglobulin, GLYCEROL, TRIETHYLENE GLYCOL Authors: Guthertz, N. Deposit date: 2021-02-23 Release date: 2022-08-03 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
6U7F	HCoV-229E RBD Class IV in complex with human APN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... Authors: Tomlinson, A.C.A, Li, Z, Rini, J.M. Deposit date: 2019-09-02 Release date: 2019-11-13 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The human coronavirus HCoV-229E S-protein structure and receptor binding. Elife, 8, 2019
3DSX	Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with di-prenylated peptide Ser-Cys(GG)-Ser-Cys(GG) derivated from Rab7 Descriptor: CALCIUM ION, GERAN-8-YL GERAN, Geranylgeranyl transferase type-2 subunit alpha, ... Authors: Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W. Deposit date: 2008-07-14 Release date: 2008-09-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation Embo J., 27, 2008
7NMV	Crystal structure of beta-2-microglobulin D76Q mutant Descriptor: Beta-2-microglobulin Authors: Guthertz, N. Deposit date: 2021-02-23 Release date: 2022-08-03 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.51 Å) Cite: The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
7NMY	Crystal structure of beta-2-microglobulin D76Y mutant Descriptor: Beta-2-microglobulin Authors: Guthertz, N. Deposit date: 2021-02-23 Release date: 2022-08-03 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.25 Å) Cite: The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
6U8B	Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction Descriptor: 3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic acid, WD repeat-containing protein 5 Authors: Zhao, B, Wang, F. Deposit date: 2019-09-04 Release date: 2019-12-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.261 Å) Cite: Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction. J.Med.Chem., 62, 2019
6U8P	Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA Descriptor: CpGpA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... Authors: Gao, L, Song, J. Deposit date: 2019-09-05 Release date: 2020-06-10 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020

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