PDB: 13413 resultsInfo pagesStatus searchChemie searchBIRD

---

8WAX	De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt downstream of TSS Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-08 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
8WAY	De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-08 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
8WAW	De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-08 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
8WAT	De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-08 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (2.82 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
8WB0	De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-08 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
8WAU	De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt downstream of TSS Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-08 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
5E17	T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7) Descriptor: DNA (27-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-09-29 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351, 2016
5E18	T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8) Descriptor: DNA (28-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-09-29 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351, 2016
5WE4	70S ribosome-EF-Tu wt complex with GppNHp Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Fislage, M, Brown, Z, Frank, J. Deposit date: 2017-07-07 Release date: 2018-04-25 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5WDT	70S ribosome-EF-Tu H84A complex with GppNHp Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Fislage, M, Brown, Z, Frank, J. Deposit date: 2017-07-06 Release date: 2018-04-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3 Å) Cite: Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
6M99	In situ structure of transcriptional enzyme complex and asymmetric inner capsid protein of aquareovirus at primed state Descriptor: PHOSPHATE ION, Putative core protein NTPase/VP5, VP2, ... Authors: Ding, K, Zhou, Z.H. Deposit date: 2018-08-23 Release date: 2018-09-05 Last modified: 2019-11-27 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: In SituStructures of the Polymerase Complex and RNA Genome Show How Aquareovirus Transcription Machineries Respond to Uncoating. J. Virol., 92, 2018
2PQF	Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid Descriptor: 3-AMINOBENZOIC ACID, CITRIC ACID, Poly [ADP-ribose] polymerase 12 Authors: Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) Deposit date: 2007-05-02 Release date: 2007-05-15 Last modified: 2015-04-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015
1UK0	Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor Descriptor: 2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE, Poly [ADP-ribose] polymerase-1 Authors: Kinoshita, T. Deposit date: 2003-08-13 Release date: 2004-01-27 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase. Febs Lett., 556, 2004
1UK1	Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor Descriptor: 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1 Authors: Kinoshita, T. Deposit date: 2003-08-14 Release date: 2004-09-14 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase J.Med.Chem., 47, 2004
7NWI	Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S Descriptor: 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... Authors: Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. Deposit date: 2021-03-16 Release date: 2021-07-07 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
8HK1	The cryo-EM structure of human pre-17S U2 snRNP Descriptor: ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... Authors: Zhang, X, Zhan, X, Shi, Y. Deposit date: 2022-11-24 Release date: 2023-03-08 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
4WC3	Structure of tRNA-processing enzyme complex 1 Descriptor: Poly A polymerase, RNA 76-mer Authors: Yamashita, S, Tomita, K. Deposit date: 2014-09-04 Release date: 2015-04-15 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
4WC7	Structure of tRNA-processing enzyme complex 5 Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Poly A polymerase, RNA (75-MER) Authors: Yamashita, S, Tomita, K. Deposit date: 2014-09-04 Release date: 2015-04-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.102 Å) Cite: Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
7EGC	p53-bound TFIID-based holo PIC on HDM2 promoter Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... Authors: Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. Deposit date: 2021-03-24 Release date: 2021-05-12 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
6WMP	F. tularensis RNAPs70-iglA DNA complex Descriptor: DNA NT-strand, DNA T-strand, DNA-directed RNA polymerase subunit alpha 1, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WMT	F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.43 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WMU	E. coli RNAPs70-SspA-gadA DNA complex Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WMR	F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
4WC2	Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, Poly A polymerase, ... Authors: Yamashita, S, Tomita, K. Deposit date: 2014-09-04 Release date: 2015-04-15 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
4X0A	Structure of tRNA-processing enzyme complex 6 Descriptor: Poly A polymerase, RNA (73-MER) Authors: Yamashita, S, Tomita, K. Deposit date: 2014-11-21 Release date: 2015-04-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.505 Å) Cite: Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015

<111112113114115116117118119120121122123124125126>