8WAY

De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS

Summary for 8WAY

• Entry DOI: 10.2210/pdb8way/pdb
• Related: 7EGB 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS 8WAT 8WAU 8WAV 8WAW 8WAX 8WAZ 8WB0
• EMDB information: 31111 37395 37396 37398 37399 37400 37401 37402 37403 37404 37405 37406 37407 37408 37409 37410 37411 37412 37413
• Related PRD ID: PRD_000201
• Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit E, ... (21 entities in total)
• Functional Keywords: transcribing complex, de novo transcription initiation, early elongation complex (eec), transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 18
• Total formula weight: 671383.81

Authors

Chen, X.,Liu, W.,Wang, Q.,Wang, X.,Ren, Y.,Qu, X.,Li, W.,Xu, Y. (deposition date: 2023-09-08, release date: 2023-12-06, Last modification date: 2024-01-03)

• Primary citation: Chen, X.,Liu, W.,Wang, Q.,Wang, X.,Ren, Y.,Qu, X.,Li, W.,Xu, Y.; Structural visualization of transcription initiation in action.; Science, 382:eadi5120-eadi5120, 2023; PubMed: 38127763; DOI: 10.1126/science.adi5120

Experimental method

ELECTRON MICROSCOPY (2.85 Å)