Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8BTT
DownloadVisualize
BU of 8btt by Molmil
Structure of human RTCB
Descriptor: MANGANESE (II) ION, RNA-splicing ligase RtcB homolog
Authors:Kopp, J, Gerber, J.L, Peschek, J.
Deposit date:2022-11-30
Release date:2023-12-13
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease.
Nat Commun, 15, 2024
7VB2
DownloadVisualize
BU of 7vb2 by Molmil
Solution structure of human ribosomal protein uL11
Descriptor: 60S ribosomal protein L12
Authors:Lee, K.M, Wong, K.B.
Deposit date:2021-08-30
Release date:2022-04-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The flexible N-terminal motif of uL11 unique to eukaryotic ribosomes interacts with P-complex and facilitates protein translation.
Nucleic Acids Res., 50, 2022
8B98
DownloadVisualize
BU of 8b98 by Molmil
Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5483
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, ...
Authors:Carrasco, K, Betzi, S, Morelli, X.
Deposit date:2022-10-05
Release date:2024-04-03
Method:X-RAY DIFFRACTION (1.495 Å)
Cite:Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5464
To Be Published
8B96
DownloadVisualize
BU of 8b96 by Molmil
Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5464
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, ...
Authors:Carrasco, K, Betzi, S, Morelli, X.
Deposit date:2022-10-05
Release date:2024-04-03
Method:X-RAY DIFFRACTION (1.338 Å)
Cite:Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5464
To Be Published
8BOX
DownloadVisualize
BU of 8box by Molmil
LSD1-CoREST in complex with AW4 and SNAG peptide
Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, Zinc finger protein SNAI1, ...
Authors:Caroli, J, Mattevi, A.
Deposit date:2022-11-15
Release date:2024-06-05
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published
8BOP
DownloadVisualize
BU of 8bop by Molmil
LSD1-CoREST in complex with AW4, long soaking
Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[7,8-dimethyl-2,4-bis(oxidanylidene)-5-[3-[4-(3-phenylphenyl)phenyl]propanoyl]-1~{H}-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate
Authors:Caroli, J, Mattevi, A.
Deposit date:2022-11-15
Release date:2024-06-05
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published
8C9J
DownloadVisualize
BU of 8c9j by Molmil
Crystal structure of human NQO1 by serial femtosecond crystallography
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1
Authors:Martin-Garcia, J.M, Grieco, A, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Pey, A, Botha, S, Ros, A.
Deposit date:2023-01-23
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.
Lab Chip, 23, 2023
2FC0
DownloadVisualize
BU of 2fc0 by Molmil
WRN exonuclease, Mn dGMP complex
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Werner syndrome helicase
Authors:Perry, J.J, Tainer, J.A.
Deposit date:2005-12-10
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.
Nat.Struct.Mol.Biol., 13, 2006
2FBY
DownloadVisualize
BU of 2fby by Molmil
WRN exonuclease, Eu complex
Descriptor: EUROPIUM (III) ION, Werner syndrome helicase
Authors:Perry, J.J.
Deposit date:2005-12-10
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.
Nat.Struct.Mol.Biol., 13, 2006
2AKM
DownloadVisualize
BU of 2akm by Molmil
Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Gamma enolase, MAGNESIUM ION, ...
Authors:Qin, J, Chai, G, Brewer, J.M, Lovelace, L.L.
Deposit date:2005-08-03
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
2CPJ
DownloadVisualize
BU of 2cpj by Molmil
Solution structure of the N-terminal RNA recognition motif of NonO
Descriptor: Non-POU domain-containing octamer-binding protein
Authors:Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-19
Release date:2005-11-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal RNA recognition motif of NonO
To be Published
2CPR
DownloadVisualize
BU of 2cpr by Molmil
Solution structure of the HRDC domain of human Exosome component 10
Descriptor: Exosome component 10
Authors:Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-19
Release date:2005-11-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the HRDC domain of human Exosome component 10
To be Published
2GNQ
DownloadVisualize
BU of 2gnq by Molmil
Structure of wdr5
Descriptor: CHLORIDE ION, WD-repeat protein 5
Authors:Min, J, Schuetz, A, Allali-Hassani, A, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-04-10
Release date:2006-06-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2H0K
DownloadVisualize
BU of 2h0k by Molmil
Crystal Structure of a Mutant of Rat Annexin A5
Descriptor: Annexin A5, CALCIUM ION
Authors:Granier, T, Langlois D'Estaintot, B, Gallois, B, Tessier, B, Brisson, A.
Deposit date:2006-05-15
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair.
Nat Commun, 2, 2011
2CPL
DownloadVisualize
BU of 2cpl by Molmil
SIMILARITIES AND DIFFERENCES BETWEEN HUMAN CYCLOPHILIN A AND OTHER BETA-BARREL STRUCTURES. STRUCTURAL REFINEMENT AT 1.63 ANGSTROMS RESOLUTION
Descriptor: CYCLOPHILIN A
Authors:Ke, H.
Deposit date:1992-06-30
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Similarities and differences between human cyclophilin A and other beta-barrel structures. Structural refinement at 1.63 A resolution.
J.Mol.Biol., 228, 1992
5U2E
DownloadVisualize
BU of 5u2e by Molmil
BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535
Descriptor: Bromodomain-containing protein 4, ethyl 4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]benzoate
Authors:Andrews, F.H, Kutateladze, T.G.
Deposit date:2016-11-30
Release date:2017-02-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2CUP
DownloadVisualize
BU of 2cup by Molmil
Solution structure of the Skeletal muscle LIM-protein 1
Descriptor: Skeletal muscle LIM-protein 1, ZINC ION
Authors:Niraula, T.N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-27
Release date:2005-11-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Skeletal muscle LIM-protein 1
To be Published
2CYH
DownloadVisualize
BU of 2cyh by Molmil
CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE ALA-PRO
Descriptor: ALANINE, CYCLOPHILIN A, PROLINE
Authors:Zhao, Y, Ke, H.
Deposit date:1996-02-27
Release date:1996-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.
Biochemistry, 35, 1996
5TSO
DownloadVisualize
BU of 5tso by Molmil
CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM PIG MUSCLE COMPLEXED WITH ORTHOPHENANTHROLINE AT 1.90 ANGSTROM RESOLUTION
Descriptor: 1,10-PHENANTHROLINE, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ...
Authors:Dimova, M, Devedjiev, Y.D.
Deposit date:2016-10-30
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Novel Enhancer Binding Site Found In Bacteria And Eukaryota But Not In Archea.
To Be Published
2CR9
DownloadVisualize
BU of 2cr9 by Molmil
Solution structure of WGR domain of poly(ADP-ribose) polymerase-1
Descriptor: Poly [ADP-ribose] polymerase-1
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-20
Release date:2005-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of WGR domain of poly(ADP-ribose) polymerase-1
To be published
2CSF
DownloadVisualize
BU of 2csf by Molmil
Solution structure of the second CUT domain of human SATB2
Descriptor: DNA-binding protein SATB2
Authors:Inoue, K, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-21
Release date:2005-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second CUT domain of human SATB2
To be Published
2CSH
DownloadVisualize
BU of 2csh by Molmil
Solution structure of tandem repeat of the zf-C2H2 domains of human zinc finger protein 297B
Descriptor: ZINC ION, Zinc finger protein 297B
Authors:Inoue, K, Saitoh, K, Hayashi, F, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-21
Release date:2005-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of tandem repeat of the zf-C2H2 domains of human zinc finger protein 297B
To be Published
2HVZ
DownloadVisualize
BU of 2hvz by Molmil
Solution structure of the RRM domain of SR rich factor 9G8
Descriptor: Splicing factor, arginine/serine-rich 7
Authors:Tintaru, A.M, Hautbergue, G.M, Golovanov, A.P, Lian, L.Y, Wilson, S.A.
Deposit date:2006-07-31
Release date:2006-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8.
Embo J., 25, 2006
2BMC
DownloadVisualize
BU of 2bmc by Molmil
Aurora-2 T287D T288D complexed with PHA-680632
Descriptor: (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE, SERINE THREONINE-PROTEIN KINASE 6
Authors:Cameron, A.D, Izzo, G, Sagliano, A, Rusconi, L, Storici, P, Fancelli, D, Berta, D, Bindi, S, Catana, C, Forte, B, Giordano, P, Mantegani, S, Meroni, M, Moll, J, Pittala, V, Severino, D, Tonani, R, Varasi, M, Vulpetti, A, Vianello, P.
Deposit date:2005-03-11
Release date:2005-03-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition.
J.Med.Chem., 48, 2005
2FBV
DownloadVisualize
BU of 2fbv by Molmil
WRN exonuclease, Mn complex
Descriptor: MANGANESE (II) ION, Werner syndrome helicase
Authors:Perry, J.J.
Deposit date:2005-12-10
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.
Nat.Struct.Mol.Biol., 13, 2006

223532

PDB entries from 2024-08-07

PDB statisticsPDBj update infoContact PDBjnumon