2VDB
| Structure of human serum albumin with S-naproxen and the GA module | Descriptor: | (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, DECANOIC ACID, PEPTOSTREPTOCOCCAL ALBUMIN-BINDING PROTEIN, ... | Authors: | Lejon, S, Cramer, J.F, Nordberg, P.A. | Deposit date: | 2007-10-04 | Release date: | 2008-02-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural Basis for the Binding of Naproxen to Human Serum Albumin in the Presence of Fatty Acids and the Ga Module. Acta Crystallogr.,Sect.F, 64, 2008
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5L01
| Tryptophan 5-hydroxylase in complex with inhibitor (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid | Descriptor: | (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid, FE (III) ION, Tryptophan 5-hydroxylase 1 | Authors: | Stein, A.J, Goldberg, D.R, De Lombaert, S, Holt, M.C. | Deposit date: | 2016-07-26 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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5L2H
| Crystal Structure of W26A mutant of anti-EGFR Centyrin P54AR4-83v2 | Descriptor: | Centyrin, GLYCEROL | Authors: | Cardoso, R.M.F, Goldberg, S.D, O Neil, K.T, Gilliland, G.L. | Deposit date: | 2016-08-01 | Release date: | 2016-11-02 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8013 Å) | Cite: | Engineering a targeted delivery platform using Centyrins. Protein Eng. Des. Sel., 29, 2016
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1K8Q
| CRYSTAL STRUCTURE OF DOG GASTRIC LIPASE IN COMPLEX WITH A PHOSPHONATE INHIBITOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Triacylglycerol lipase, gastric, ... | Authors: | Roussel, A, Miled, N, Berti-Dupuis, L, Riviere, M, Spinelli, S, Berna, P, Gruber, V, Verger, R, Cambillau, C. | Deposit date: | 2001-10-25 | Release date: | 2002-03-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitor. J.Biol.Chem., 277, 2002
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3IBP
| The Crystal Structure of the Dimerization Domain of Escherichia coli Structural Maintenance of Chromosomes Protein MukB | Descriptor: | AMMONIUM ION, Chromosome partition protein mukB | Authors: | Li, Y, Schoeffler, A.J, Berger, J.M, Oakley, M.G. | Deposit date: | 2009-07-16 | Release date: | 2010-01-26 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.099 Å) | Cite: | The crystal structure of the hinge domain of the Escherichia coli structural maintenance of chromosomes protein MukB. J.Mol.Biol., 395, 2010
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1YSW
| Solution structure of the anti-apoptotic protein Bcl-2 complexed with an acyl-sulfonamide-based ligand | Descriptor: | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2 | Authors: | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | Deposit date: | 2005-02-09 | Release date: | 2005-06-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature, 435, 2005
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2X7Q
| The conserved Candida albicans CA3427 gene product defines a new family of proteins exhibiting the generic periplasmic binding protein structural fold | Descriptor: | CALCIUM ION, GLYCEROL, POSSIBLE THIAMINE BIOSYNTHESIS ENZYME | Authors: | Santini, S, Monchois, V, Mouz, N, Rousselle, T, Claverie, J.M, Abergel, C. | Deposit date: | 2010-03-03 | Release date: | 2011-03-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Conserved Candida Albicans Ca3427 Gene Product Defines a New Family of Proteins Exhibiting the Generic Periplasmic Binding Protein Structural Fold Plos One, 6, 2011
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1YSN
| Solution structure of the anti-apoptotic protein Bcl-xL complexed with an acyl-sulfonamide-based ligand | Descriptor: | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X | Authors: | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | Deposit date: | 2005-02-08 | Release date: | 2005-06-07 | Last modified: | 2023-11-29 | Method: | SOLUTION NMR | Cite: | An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature, 435, 2005
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2X7P
| The Conserved Candida albicans CA3427 Gene Product Defines a New Family of Proteins Exhibiting the Generic Periplasmic Binding Protein Structural Fold | Descriptor: | 2-(2-ETHOXYETHOXY)ETHANOL, ACETIC ACID, CALCIUM ION, ... | Authors: | Santini, S, Monchois, V, Mouz, N, Rousselle, T, Claverie, J.M, Abergel, C. | Deposit date: | 2010-03-03 | Release date: | 2011-03-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | The Conserved Candida Albicans Ca3427 Gene Product Defines a New Family of Proteins Exhibiting the Generic Periplasmic Binding Protein Structural Fold Plos One, 6, 2011
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4PWB
| Phl p 4 I153V variant, a glucose oxidase, pressurized with Xenon | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Pollen allergen Phl p 4.0202, ... | Authors: | Zafred, D, Keller, W, Macheroux, P. | Deposit date: | 2014-03-19 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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221L
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4C5Z
| Crystal structure of A. niger ochratoxinase | Descriptor: | OCHRATOXINASE | Authors: | Dobritzsch, D, Wang, H, Schneider, G, Yu, S. | Deposit date: | 2013-09-17 | Release date: | 2014-07-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme. Biochem.J., 462, 2014
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2WXC
| The folding mechanism of BBL: Plasticity of transition-state structure observed within an ultrafast folding protein family. | Descriptor: | DIHYDROLIPOYLTRANSSUCCINASE | Authors: | Neuweiler, H, Sharpe, T.D, Rutherford, T.J, Johnson, C.M, Allen, M.D, Ferguson, N, Fersht, A.R. | Deposit date: | 2009-11-06 | Release date: | 2009-11-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Folding Mechanism of Bbl: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family. J.Mol.Biol., 390, 2009
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7P9T
| Crystal structure of CD73 in complex with dCMP in the open form | Descriptor: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 5'-nucleotidase, CALCIUM ION, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-27 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PB5
| Crystal structure of CD73 in complex with UMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-30 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PBB
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7PA4
| Crystal structure of CD73 in complex with CMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-28 | Release date: | 2021-10-13 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7P9N
| Crystal structure of CD73 in complex with AMP in the open form | Descriptor: | 5'-nucleotidase, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-27 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PBA
| Crystal structure of CD73 in complex with IMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-08-01 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7P9R
| Crystal structure of CD73 in complex with GMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-27 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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2IY3
| Structure of the E. Coli Signal Regognition Particle | Descriptor: | 4.5S RNA, SIGNAL SEQUENCE, Signal recognition particle protein,Signal recognition particle 54 kDa protein | Authors: | Schaffitzel, C, Oswald, M, Berger, I, Ishikawa, T, Abrahams, J.P, Koerten, H.K, Koning, R.I, Ban, N. | Deposit date: | 2006-07-12 | Release date: | 2006-11-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (16 Å) | Cite: | Structure of the E. Coli Signal Recognition Particle Bound to a Translating Ribosome Nature, 444, 2006
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4P5K
| Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity | Descriptor: | HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ... | Authors: | Clayton, G.M, Wang, Y, Crawford, F, Novikov, A, Wimberly, B.T, Kieft, J.S, Falta, M.T, Bowerman, N.A, Marrack, P, Fontenot, A.P, Dai, S, Kappler, J.W. | Deposit date: | 2014-03-17 | Release date: | 2015-01-21 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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3J1V
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2IJ0
| Structural basis of T cell specificity and activation by the bacterial superantigen toxic shock syndrome toxin-1 | Descriptor: | Toxic shock syndrome toxin-1, penultimate affinity-matured variant of hVbeta 2.1, D10 | Authors: | Moza, B, Varma, A.K, Buonpane, R.A, Zhu, P, Herfst, C.A, Nicholson, M.J, Wilbuer, A.K, Nulifer, S, Wucherpfenning, K.W, McCormick, J.K, Kranz, D.M, Sundberg, E.J. | Deposit date: | 2006-09-28 | Release date: | 2007-02-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1. Embo J., 26, 2007
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5UBJ
| Structure of an alpha-L-arabinofuranosidase (GH62) from Aspergillus nidulans | Descriptor: | Alpha-L-arabinofuranosidase axhA-2, CALCIUM ION | Authors: | Liberato, M.V, Contesini, F.J, Damasio, A.R, Squina, F.M. | Deposit date: | 2016-12-20 | Release date: | 2017-09-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and functional characterization of a highly secreted alpha-l-arabinofuranosidase (GH62) from Aspergillus nidulans grown on sugarcane bagasse. Biochim. Biophys. Acta, 1865, 2017
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